Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_2878Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureOsteosarcoma cell lineHOS5.0E+3 cells per wellNAMTT assay10 MOI5% cell survivalNoNoNA No responseNANANANA23816608
OV_2879Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineIMR-55.0E+3 cells per wellNAMTT assay0.01 MOI78% cell survivalNoNoNA No responseNANANANA23816608
OV_2880Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineIMR-55.0E+3 cells per wellNAMTT assay0.1 MOI70% cell survivalNoNoNA No responseNANANANA23816608
OV_2881Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineIMR-55.0E+3 cells per wellNAMTT assay1 MOI60% cell survivalNoNoNA No responseNANANANA23816608
OV_2882Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineIMR-55.0E+3 cells per wellNAMTT assay10 MOI50% cell survivalNoNoNA No responseNANANANA23816608
OV_2883Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineIMR-325.0E+3 cells per wellNAMTT assay0.01 MOI50% cell survivalNoNoNA No responseNANANANA23816608
OV_2884Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineIMR-325.0E+3 cells per wellNAMTT assay0.1 MOI42% cell survivalNoNoNA No responseNANANANA23816608
OV_2885Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineIMR-325.0E+3 cells per wellNAMTT assay1 MOI38% cell survivalNoNoNA No responseNANANANA23816608
OV_2886Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineIMR-325.0E+3 cells per wellNAMTT assay10 MOI20% cell survivalNoNoNA No responseNANANANA23816608
OV_2887Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineSK-N-AS5.0E+3 cells per wellNAMTT assay0.01 MOI70% cell survivalNoNoNA No responseNANANANA23816608
OV_2888Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineSK-N-AS5.0E+3 cells per wellNAMTT assay0.1 MOI40% cell survivalNoNoNA No responseNANANANA23816608
OV_2889Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineSK-N-AS5.0E+3 cells per wellNAMTT assay1 MOI30% cell survivalNoNoNA No responseNANANANA23816608
OV_2890Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineSK-N-AS5.0E+3 cells per wellNAMTT assay10 MOI20% cell survivalNoNoNA No responseNANANANA23816608
OV_2891Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineSKNBE25.0E+3 cells per wellNAMTT assay0.01 MOI50% cell survivalNoNoNA No responseNANANANA23816608
OV_2892Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineSKNBE25.0E+3 cells per wellNAMTT assay0.1 MOI40% cell survivalNoNoNA No responseNANANANA23816608
OV_2893Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineSKNBE25.0E+3 cells per wellNAMTT assay1 MOI38% cell survivalNoNoNA No responseNANANANA23816608
OV_2894Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineSKNBE25.0E+3 cells per wellNAMTT assay10 MOI20% cell survivalNoNoNA No responseNANANANA23816608
OV_2895Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell lineBT16GFPFlucNANANANANACD-1 mice xenograft for cell line (1.0E+5) 5.0E+7 pfuNA Significant reduction in tumor volumeNANANANA23816608
OV_2896Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoLaboratory grown own cultureNeuroblastoma cell line SKNASmCherryFlucSK-N-ASmCherryFlucNANANANANACB17 SCID mice xenograft for cell line (5.0E+6)5.0E+7 pfuNA Significant reduction in tumor volumeNANANANA23816608
OV_3045Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman cervical cancer cell lineHeLa3.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI30% cell viabilityNoNoNA No responseNANANANA31011628
OV_3046Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman cervical cancer cell lineHeLa3.0E+5 cells per wellNATrypan blue assay10⁻³ MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3047Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman cervical cancer cell lineHeLa3.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3048Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineLoVo3.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI100% cell viabilityNoNoNA No responseNANANANA31011628
OV_3049Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineLoVo3.0E+5 cells per wellNATrypan blue assay10⁻³ MOI70% cell viabilityNoNoNA No responseNANANANA31011628
OV_3050Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineLoVo3.0E+5 cells per wellNATrypan blue assay10⁻² MOI15% cell viabilityNoNoNA No responseNANANANA31011628
OV_3051Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman lung cancer cell lineA5493.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI18% cell viabilityNoNoNA No responseNANANANA31011628
OV_3052Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman lung cancer cell lineA5493.0E+5 cells per wellNATrypan blue assay10⁻³ MOI10% cell viabilityNoNoNA No responseNANANANA31011628
OV_3053Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman lung cancer cell lineA5493.0E+5 cells per wellNATrypan blue assay10⁻² MOI1% cell viabilityNoNoNA No responseNANANANA31011628
OV_3054Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman glioblastoma cell lineU-87 MG3.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI30% cell viabilityNoNoNA No responseNANANANA31011628
OV_3055Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman glioblastoma cell lineU-87 MG3.0E+5 cells per wellNATrypan blue assay10⁻³ MOI10% cell viabilityNoNoNA No responseNANANANA31011628
OV_3056Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman glioblastoma cell lineU-87 MG3.0E+5 cells per wellNATrypan blue assay10⁻² MOI1% cell viabilityNoNoNA No responseNANANANA31011628
OV_3057Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman hepatocellular carcinoma cell lineHepG23.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI18% cell viabilityNoNoNA No responseNANANANA31011628
OV_3058Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman hepatocellular carcinoma cell lineHepG23.0E+5 cells per wellNATrypan blue assay10⁻³ MOI1% cell viabilityNoNoNA No responseNANANANA31011628
OV_3059Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman hepatocellular carcinoma cell lineHepG23.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3060Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman bladder cancer cell lineSW7803.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI50% cell viabilityNoNoNA No responseNANANANA31011628
OV_3061Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman bladder cancer cell lineSW7803.0E+5 cells per wellNATrypan blue assay10⁻³ MOI10% cell viabilityNoNoNA No responseNANANANA31011628
OV_3062Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman bladder cancer cell lineSW7803.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3063Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoECACCHuman eosophageal cancer cell lineOE193.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI80% cell viabilityNoNoNA No responseNANANANA31011628
OV_3064Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoECACCHuman eosophageal cancer cell lineOE193.0E+5 cells per wellNATrypan blue assay10⁻³ MOI50% cell viabilityNoNoNA No responseNANANANA31011628
OV_3065Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoECACCHuman eosophageal cancer cell lineOE193.0E+5 cells per wellNATrypan blue assay10⁻² MOI10% cell viabilityNoNoNA No responseNANANANA31011628
OV_3066Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoCantren Antoine- lacassagne, FranceHuman head and neck squamous cell carcinoma cell lineCAL333.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI18% cell viabilityNoNoNA No responseNANANANA31011628
OV_3067Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoCantren Antoine- lacassagne, FranceHuman head and neck squamous cell carcinoma cell lineCAL333.0E+5 cells per wellNATrypan blue assay10⁻³ MOI1% cell viabilityNoNoNA No responseNANANANA31011628
OV_3068Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoCantren Antoine- lacassagne, FranceHuman head and neck squamous cell carcinoma cell lineCAL333.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3069Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman stomach cancer cell lineHs746T3.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI18% cell viabilityNoNoNA No responseNANANANA31011628
OV_3070Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman stomach cancer cell lineHs746T3.0E+5 cells per wellNATrypan blue assay10⁻³ MOI1% cell viabilityNoNoNA No responseNANANANA31011628
OV_3071Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman stomach cancer cell lineHs746T3.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3072Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineHCT-1163.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI30% cell viabilityNoNoNA No responseNANANANA31011628
OV_3073Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineHCT-1163.0E+5 cells per wellNATrypan blue assay10⁻³ MOI5% cell viabilityNoNoNA No responseNANANANA31011628
OV_3074Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineHCT-1163.0E+5 cells per wellNATrypan blue assay10⁻² MOI1% cell viabilityNoNoNA No responseNANANANA31011628
OV_3075Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman cervical cancer cell lineHeLa3.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI18% cell viabilityNoNoNA No responseNANANANA31011628
OV_3076Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman cervical cancer cell lineHeLa3.0E+5 cells per wellNATrypan blue assay10⁻³ MOI1% cell viabilityNoNoNA No responseNANANANA31011628
OV_3077Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman cervical cancer cell lineHeLa3.0E+5 cells per wellNATrypan blue assay10⁻² MOI1% cell viabilityNoNoNA No responseNANANANA31011628
OV_3078Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineLoVo3.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI100% cell viabilityNoNoNA No responseNANANANA31011628
OV_3079Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineLoVo3.0E+5 cells per wellNATrypan blue assay10⁻³ MOI70% cell viabilityNoNoNA No responseNANANANA31011628
OV_3080Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineLoVo3.0E+5 cells per wellNATrypan blue assay10⁻² MOI15% cell viabilityNoNoNA No responseNANANANA31011628
OV_3081Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman lung cancer cell lineA5493.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI30% cell viabilityNoNoNA No responseNANANANA31011628
OV_3082Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman lung cancer cell lineA5493.0E+5 cells per wellNATrypan blue assay10⁻³ MOI15% cell viabilityNoNoNA No responseNANANANA31011628
OV_3083Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman lung cancer cell lineA5493.0E+5 cells per wellNATrypan blue assay10⁻² MOI5% cell viabilityNoNoNA No responseNANANANA31011628
OV_3084Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman glioblastoma cell lineU-87 MG3.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI30% cell viabilityNoNoNA No responseNANANANA31011628
OV_3085Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman glioblastoma cell lineU-87 MG3.0E+5 cells per wellNATrypan blue assay10⁻³ MOI15% cell viabilityNoNoNA No responseNANANANA31011628
OV_3086Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman glioblastoma cell lineU-87 MG3.0E+5 cells per wellNATrypan blue assay10⁻² MOI5% cell viabilityNoNoNA No responseNANANANA31011628
OV_3087Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman hepatocellular carcinoma cell lineHepG23.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI15% cell viabilityNoNoNA No responseNANANANA31011628
OV_3088Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman hepatocellular carcinoma cell lineHepG23.0E+5 cells per wellNATrypan blue assay10⁻³ MOI1% cell viabilityNoNoNA No responseNANANANA31011628
OV_3089Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman hepatocellular carcinoma cell lineHepG23.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3090Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman bladder cancer cell lineSW7803.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI45% cell viabilityNoNoNA No responseNANANANA31011628
OV_3091Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman bladder cancer cell lineSW7803.0E+5 cells per wellNATrypan blue assay10⁻³ MOI15% cell viabilityNoNoNA No responseNANANANA31011628
OV_3092Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman bladder cancer cell lineSW7803.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3093Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoECACCHuman eosophageal cancer cell lineOE193.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI85% cell viabilityNoNoNA No responseNANANANA31011628
OV_3094Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoECACCHuman eosophageal cancer cell lineOE193.0E+5 cells per wellNATrypan blue assay10⁻³ MOI45% cell viabilityNoNoNA No responseNANANANA31011628
OV_3095Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoECACCHuman eosophageal cancer cell lineOE193.0E+5 cells per wellNATrypan blue assay10⁻² MOI5% cell viabilityNoNoNA No responseNANANANA31011628
OV_3096Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoCantren Antoine- lacassagne, FranceHuman head and neck squamous cell carcinoma cell lineCAL333.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI18% cell viabilityNoNoNA No responseNANANANA31011628
OV_3097Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoCantren Antoine- lacassagne, FranceHuman head and neck squamous cell carcinoma cell lineCAL333.0E+5 cells per wellNATrypan blue assay10⁻³ MOI2% cell viabilityNoNoNA No responseNANANANA31011628
OV_3098Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoCantren Antoine- lacassagne, FranceHuman head and neck squamous cell carcinoma cell lineCAL333.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3099Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman stomach cancer cell lineHs746T3.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI18% cell viabilityNoNoNA No responseNANANANA31011628
OV_3100Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman stomach cancer cell lineHs746T3.0E+5 cells per wellNATrypan blue assay10⁻³ MOI2% cell viabilityNoNoNA No responseNANANANA31011628
OV_3101Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman stomach cancer cell lineHs746T3.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3102Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineHCT-1163.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI30% cell viabilityNoNoNA No responseNANANANA31011628
OV_3103Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineHCT-1163.0E+5 cells per wellNATrypan blue assay10⁻³ MOI10% cell viabilityNoNoNA No responseNANANANA31011628
OV_3104Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman colon cancer cell lineHCT-1163.0E+5 cells per wellNATrypan blue assay10⁻² MOI1% cell deathNoNoNA No responseNANANANA31011628
OV_3105Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman colon cancer cell lineLoVoNANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 500mm after 50 daysIntravenousNANANA31011628
OV_3106Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman colon cancer cell lineLoVoNANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to 500mm after 50 daysIntravenousNANANA31011628
OV_3107Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoECACCHuman colon cancer cell lineOE19NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 1000 mm after 50 daysIntravenousNANANA31011628
OV_3108Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoECACCHuman colon cancer cell lineOE19NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to 250 mm after 50 daysIntravenousNANANA31011628
OV_3109Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman bladder cancer cell lineSW780NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628
OV_3110Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman bladder cancer cell lineSW780NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628
OV_3111Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman hepatocellular carcinoma cell lineHepG2NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 1500 mm after 50 daysIntravenousNANANA31011628
OV_3112Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman hepatocellular carcinoma cell lineHepG2NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 1000 mm after 50 daysIntravenousNANANA31011628
OV_3113Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman stomach cancer cell lineHs746TNANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 3500 mm after 50 daysIntravenousNANANA31011628
OV_3114Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman stomach cancer cell lineHs746TNANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 1000 mm after 50 daysIntravenousNANANA31011628
OV_3115Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoCantren Antoine- lacassagne, FranceHuman head and neck squamous cell carcinoma cell lineCAL33NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628
OV_3116Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoCantren Antoine- lacassagne, FranceHuman head and neck squamous cell carcinoma cell lineCAL33NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628
OV_3117Vaccinia virusVaccinia virus deltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman colon cancer cell lineHCT-116NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 500 mm after 50 daysIntravenousNANANA31011628
OV_3118Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman colon cancer cell lineHCT-116NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628
OV_3189Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman edwig sarcoma cell lineRD-ES90% confluenceNACrystal violet staining and absorbance at 595 nm0.0001 MOI75% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3190Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman edwig sarcoma cell lineRD-ES90% confluenceNACrystal violet staining and absorbance at 595 nm0.001 MOI50% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3191Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman edwig sarcoma cell lineRD-ES90% confluenceNACrystal violet staining and absorbance at 595 nm0.01 MOI45% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3192Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman edwig sarcoma cell lineRD-ES90% confluenceNACrystal violet staining and absorbance at 595 nm0.1 MOI45% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3193Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman edwig sarcoma cell lineRD-ES90% confluenceNACrystal violet staining and absorbance at 595 nm1 MOI40% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3194Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman edwig sarcoma cell lineRD-ES90% confluenceNACrystal violet staining and absorbance at 595 nm10 MOI45% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891
OV_3219Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman bone osteosarcoma cell line143-B90% confluenceNACrystal violet staining and absorbance at 595 nm0.0001 MOI75% cell survival after 48 hoursNoNoNA No responseNANAGenration of memory immune response by incresing production of cytokinesNA28568891