Browse By Oncolytic Virus Species Result Page of OvirusTdb
The Total number of records shown on this page is 100. Click on ID to see further detail.
IDOV_2878 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineOsteosarcoma cell line | Cell lineHOS | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result5% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2879 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineIMR-5 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result78% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2880 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineIMR-5 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result70% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2881 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineIMR-5 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result60% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2882 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineIMR-5 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result50% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2883 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineIMR-32 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result50% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2884 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineIMR-32 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result42% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2885 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineIMR-32 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result38% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2886 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineIMR-32 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2887 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineSK-N-AS | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result70% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2888 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineSK-N-AS | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result40% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2889 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineSK-N-AS | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result30% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2890 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineSK-N-AS | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2891 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineSKNBE2 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result50% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2892 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineSKNBE2 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result40% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2893 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineSKNBE2 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result38% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2894 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineSKNBE2 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2895 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line | Cell lineBT16GFPFluc | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismCD-1 mice xenograft for cell line (1.0E+5) | In-vivo virus concentration5.0E+7 pfu | In-vivo toxicityNA | In-vivo resultSignificant reduction in tumor volume | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_2896 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineNeuroblastoma cell line SKNASmCherryFluc | Cell lineSK-N-ASmCherryFluc | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismCB17 SCID mice xenograft for cell line (5.0E+6) | In-vivo virus concentration5.0E+7 pfu | In-vivo toxicityNA | In-vivo resultSignificant reduction in tumor volume | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID23816608 |
IDOV_3045 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cervical cancer cell line | Cell lineHeLa | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3046 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cervical cancer cell line | Cell lineHeLa | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3047 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cervical cancer cell line | Cell lineHeLa | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3048 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineLoVo | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3049 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineLoVo | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result70% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3050 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineLoVo | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result15% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3051 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result18% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3052 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3053 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result1% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3054 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman glioblastoma cell line | Cell lineU-87 MG | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3055 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman glioblastoma cell line | Cell lineU-87 MG | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3056 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman glioblastoma cell line | Cell lineU-87 MG | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result1% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3057 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHepG2 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result18% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3058 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHepG2 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result1% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3059 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHepG2 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3060 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bladder cancer cell line | Cell lineSW780 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result50% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3061 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bladder cancer cell line | Cell lineSW780 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3062 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bladder cancer cell line | Cell lineSW780 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3063 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineECACC | Origin of cell lineHuman eosophageal cancer cell line | Cell lineOE19 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result80% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3064 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineECACC | Origin of cell lineHuman eosophageal cancer cell line | Cell lineOE19 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result50% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3065 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineECACC | Origin of cell lineHuman eosophageal cancer cell line | Cell lineOE19 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3066 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCantren Antoine- lacassagne, France | Origin of cell lineHuman head and neck squamous cell carcinoma cell line | Cell lineCAL33 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result18% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3067 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCantren Antoine- lacassagne, France | Origin of cell lineHuman head and neck squamous cell carcinoma cell line | Cell lineCAL33 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result1% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3068 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCantren Antoine- lacassagne, France | Origin of cell lineHuman head and neck squamous cell carcinoma cell line | Cell lineCAL33 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3069 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman stomach cancer cell line | Cell lineHs746T | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result18% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3070 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman stomach cancer cell line | Cell lineHs746T | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result1% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3071 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman stomach cancer cell line | Cell lineHs746T | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3072 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineHCT-116 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3073 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineHCT-116 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result5% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3074 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineHCT-116 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result1% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3075 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cervical cancer cell line | Cell lineHeLa | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result18% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3076 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cervical cancer cell line | Cell lineHeLa | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result1% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3077 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cervical cancer cell line | Cell lineHeLa | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result1% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3078 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineLoVo | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3079 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineLoVo | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result70% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3080 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineLoVo | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result15% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3081 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3082 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result15% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3083 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result5% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3084 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman glioblastoma cell line | Cell lineU-87 MG | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3085 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman glioblastoma cell line | Cell lineU-87 MG | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result15% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3086 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman glioblastoma cell line | Cell lineU-87 MG | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result5% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3087 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHepG2 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result15% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3088 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHepG2 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result1% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3089 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHepG2 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3090 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bladder cancer cell line | Cell lineSW780 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result45% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3091 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bladder cancer cell line | Cell lineSW780 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result15% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3092 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bladder cancer cell line | Cell lineSW780 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3093 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineECACC | Origin of cell lineHuman eosophageal cancer cell line | Cell lineOE19 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result85% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3094 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineECACC | Origin of cell lineHuman eosophageal cancer cell line | Cell lineOE19 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result45% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3095 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineECACC | Origin of cell lineHuman eosophageal cancer cell line | Cell lineOE19 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result5% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3096 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCantren Antoine- lacassagne, France | Origin of cell lineHuman head and neck squamous cell carcinoma cell line | Cell lineCAL33 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result18% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3097 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCantren Antoine- lacassagne, France | Origin of cell lineHuman head and neck squamous cell carcinoma cell line | Cell lineCAL33 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result2% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3098 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineCantren Antoine- lacassagne, France | Origin of cell lineHuman head and neck squamous cell carcinoma cell line | Cell lineCAL33 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3099 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman stomach cancer cell line | Cell lineHs746T | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result18% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3100 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman stomach cancer cell line | Cell lineHs746T | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result2% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3101 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman stomach cancer cell line | Cell lineHs746T | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result100% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3102 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineHCT-116 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»â´ MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3103 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineHCT-116 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â³ MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3104 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineHCT-116 | Concentration of cell line3.0E+5 cells per well | In-vitro toxicityNA | AssayTrypan blue assay | In-vitro virus concentration10â»Â² MOI | In-vitro result1% cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3105 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineLoVo | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to below 500mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3106 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineLoVo | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to 500mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3107 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineECACC | Origin of cell lineHuman colon cancer cell line | Cell lineOE19 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to below 1000 mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3108 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineECACC | Origin of cell lineHuman colon cancer cell line | Cell lineOE19 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to 250 mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3109 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bladder cancer cell line | Cell lineSW780 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to below 100 mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3110 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bladder cancer cell line | Cell lineSW780 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to below 100 mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3111 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHepG2 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to below 1500 mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3112 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHepG2 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to below 1000 mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3113 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman stomach cancer cell line | Cell lineHs746T | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to below 3500 mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3114 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman stomach cancer cell line | Cell lineHs746T | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to below 1000 mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3115 | Virus nameVaccinia virus | Virus strainDeltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineCantren Antoine- lacassagne, France | Origin of cell lineHuman head and neck squamous cell carcinoma cell line | Cell lineCAL33 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to below 100 mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3116 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineCantren Antoine- lacassagne, France | Origin of cell lineHuman head and neck squamous cell carcinoma cell line | Cell lineCAL33 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to below 100 mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3117 | Virus nameVaccinia virus | Virus strainVaccinia virus deltaJ2R/FCU1 VACV | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineHCT-116 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to below 500 mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3118 | Virus nameVaccinia virus | Virus strainDeltaJ2R-I4L/FCU1 VACV (TG6002) | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of J2R and I4L gene and insertion of gene FCU1 | Virus aloneNo | Virus in combination with drug/radiationVirus strain in combination with 5-FC (200mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colon cancer cell line | Cell lineHCT-116 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBD62 mice xenograft for Lovo cell line | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume decreases to below 100 mm after 50 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID31011628 |
IDOV_3189 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman edwig sarcoma cell line | Cell lineRD-ES | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.0001 MOI | In-vitro result75% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3190 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman edwig sarcoma cell line | Cell lineRD-ES | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.001 MOI | In-vitro result50% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3191 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman edwig sarcoma cell line | Cell lineRD-ES | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.01 MOI | In-vitro result45% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3192 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman edwig sarcoma cell line | Cell lineRD-ES | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.1 MOI | In-vitro result45% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3193 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman edwig sarcoma cell line | Cell lineRD-ES | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration1 MOI | In-vitro result40% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3194 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman edwig sarcoma cell line | Cell lineRD-ES | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration10 MOI | In-vitro result45% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |
IDOV_3219 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman bone osteosarcoma cell line | Cell line143-B | Concentration of cell line90% confluence | In-vitro toxicityNA | AssayCrystal violet staining and absorbance at 595 nm | In-vitro virus concentration0.0001 MOI | In-vitro result75% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectGenration of memory immune response by incresing production of cytokines | Clinical trialNA | PMID28568891 |