Detailed description page of Selected OV_ID


OV_3093 details
Primary information
OV_IDOV_3093
Virus Name Vaccinia virus
StrainDeltaJ2R-I4L/FCU1 VACV (TG6002)
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeDeletion of J2R and I4L gene and insertion of gene FCU1
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineECACC
Origin of cell lineHuman eosophageal cancer cell line
Cell lineOE19
Concentration of cell line3
In-vitro toxicityNA
AssayTrypan blue assay
In-vitro virus concentration10⁻⁴ MOI
In-vitro result85% cell viability
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID31011628