Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1530	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1531	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.01+/- 0.003, 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75 % cell death at CI 0.126	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1532	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.83+/- 0.61, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75 % cell death at CI 0.117	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1533	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.02+/- 0.01, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75 % cell death at CI 0.249	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1534	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75 % cell death at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1535	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (17.69+/- 10.16, 1:20)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	75 % cell death at CI 0.030	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1536	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75 % cell death at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1537	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.01+/- 0.003, 1:53)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.126	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1538	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.83+/- 0.61, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.047	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1539	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.02+/- 0.01, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.285	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1540	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1541	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (17.69+/- 10.16, 1:20)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.008	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1542	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1543	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.01+/- 0.003, 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.006	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1544	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.83+/- 0.61, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.099	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1545	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.02+/- 0.01, 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.207	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1546	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1547	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (17.69+/- 10.16, 1:200)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.057	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1548	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1549	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.01+/- 0.003, 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.017	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1550	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.83+/- 0.61, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.110	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1551	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.02+/- 0.01, 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.092	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1552	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1553	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (17.69+/- 10.16, 1:200)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.007	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1554	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1555	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.01+/- 0.003, 1:533)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.054	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1556	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.83+/- 0.61, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.127	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1557	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.02+/- 0.01, 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.369	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1558	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1559	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (17.69+/- 10.16, 1:200)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.001	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1560	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1561	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(0.92+/-0.35nm, 1:5.3)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.255	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1562	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(48.40+/-23.08, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 1.749	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1563	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(1.49+/-1.09nm, 1:2)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.316	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1564	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 3.275	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1565	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(28.46+/-14.13, 1:20)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.081	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1566	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1567	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(0.92+/-0.35nm, 1:5.3)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.149	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1568	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(48.40+/-23.08, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 7.049	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1569	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(1.49+/-1.09nm, 1:2)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.056	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1570	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 1.927	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1571	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(28.46+/-14.13, 1:20)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.043	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1572	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1573	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(0.92+/-0.35nm, 1:5.3)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.089	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1574	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(48.40+/-23.08, 1:20)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1575	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(1.49+/-1.09nm, 1:2)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.019	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1576	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 1.134	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1577	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(28.46+/-14.13, 1:20)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.023	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1578	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:20)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1579	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(0.92+/-0.35nm, 1:53.3)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.069	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1580	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(48.40+/-23.08, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.133	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1581	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(1.49+/-1.09nm, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.367	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1582	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.193	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1583	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(28.46+/-14.13, 1:200)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.027	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1584	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1585	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(0.92+/-0.35nm, 1:53.3)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.045	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1586	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(48.40+/-23.08, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 1.256	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1587	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(1.49+/-1.09nm, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.052	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1588	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.651	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1589	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(28.46+/-14.13, 1:200)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.006	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1590	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1591	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(0.92+/-0.35nm, 1:53.3)	No	NCI	Human NSCLC cell line	NCIH460	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.031	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1592	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(48.40+/-23.08, 1:200)	No	NCI	Human NSCLC cell line	HOP-92	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 11.922	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1593	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(1.49+/-1.09nm, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.008	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1594	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 2.192	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1595	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(28.46+/-14.13, 1:200)	No	NCI	Human NSCLC cell line	H226	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.001	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1596	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:200)	No	NCI	Human NSCLC cell line	H322M	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1941	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.0005 MOI	100% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1943	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with NDV	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.0005 MOI	100% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1944	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with parovirus	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.0005 MOI	100% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1947	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.005 MOI	95% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1949	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with NDV	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.005 MOI	90% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1950	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with parovirus	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.005 MOI	100% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1953	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.05 MOI	90% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1955	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with NDV	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.05 MOI	30% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1956	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with parovirus	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.05 MOI	95% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1959	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.5 MOI	50% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1961	Reovirus	wild type	RNA	Reoviridae	None	No	Reovirus in combination with NDV	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.5 MOI	10% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1962	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with parovirus	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.5 MOI	50% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1965	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	2.5 MOI	30% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1967	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with NDV	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	2.5 MOI	2% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1968	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with parovirus	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	2.5 MOI	50% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1970	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	5 MOI	18% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1972	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with NDV	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	5 MOI	2% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1973	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with parovirus	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	5 MOI	2% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1976	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.0005 MOI	100% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1978	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with NDV	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.0005 MOI	100% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1979	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with parovirus	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.0005 MOI	100% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1982	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.005 MOI	97% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1984	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with NDV	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.005 MOI	80% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1985	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with parovirus	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.005 MOI	90% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1988	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.05 MOI	80% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1990	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with NDV	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.05 MOI	45% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1991	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with parovirus	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.05 MOI	50% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1994	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.5 MOI	70% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1996	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with NDV	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.5 MOI	30% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1997	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with parovirus	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.5 MOI	30% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_2000	Reovirus	Reovirus T3D	RNA	Reoviridae	None	Yes	No	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	2.5 MOI	60% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_2002	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with NDV	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	2.5 MOI	18% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_2003	Reovirus	Reovirus T3D	RNA	Reoviridae	None	No	Reovirus in combination with parovirus	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	2.5 MOI	20% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667

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