| Primary information |
|---|
| OV_ID | OV_1582 |
| Virus Name | Reovirus |
| Strain | ReoT3D |
| Virus type | RNA |
| Virus family | Reoviridae |
| Modification in virus genome | None |
| Virus alone | No |
| Virus in combination iwth drug/radiation | Virus combination with vinblastine(>100, 1:200) |
| Immune gene induction in virus genome | No |
| Source of cell line | NCI |
| Origin of cell line | Human NSCLC cell line |
| Cell line | EKVX |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | chou-Talay analysis |
| In-vitro virus concentration | Log10 pfu/cell |
| In-vitro result | 50% cell killing at CI 0.193 |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Induction of apoptosis, activation of caspase 3 |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 19594950 |