Detailed description page of Selected OV_ID


OV_1549 details
Primary information
OV_IDOV_1549
Virus Name Reovirus
StrainReoT3D
Virus typeRNA
Virus familyReoviridae
Modification in virus genomeNone
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with Gemcitabine (0.01+/- 0.003, 1:533)
Immune gene induction in virus genomeNo
Source of cell lineNCI
Origin of cell lineHuman NSCLC cell line
Cell lineNCIH460
Concentration of cell line0
In-vitro toxicityNA
Assaychou-Talay analysis
In-vitro virus concentrationLog10 pfu/cell
In-vitro result75% cell killing at CI 0.017
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis, activation of caspase 3
Immunogenic effectNA
Clinical trialNA
PMID19594950