| Primary information |
|---|
| OV_ID | OV_1988 |
| Virus Name | Reovirus |
| Strain | Reovirus T3D |
| Virus type | RNA |
| Virus family | Reoviridae |
| Modification in virus genome | None |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Human glioma cell line |
| Cell line | U373 |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | MTT assay |
| In-vitro virus concentration | 0.05 MOI |
| In-vitro result | 80% cell survival |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Virus alone and in combination enhance apoptosis |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 21607667 |