Detailed description page of Selected OV_ID


OV_1533 details
Primary information
OV_IDOV_1533
Virus Name Reovirus
StrainReoT3D
Virus typeRNA
Virus familyReoviridae
Modification in virus genomeNone
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with Gemcitabine (0.02+/- 0.01, 1:20)
Immune gene induction in virus genomeNo
Source of cell lineNCI
Origin of cell lineHuman NSCLC cell line
Cell lineNCI-H23
Concentration of cell line0
In-vitro toxicityNA
Assaychou-Talay analysis
In-vitro virus concentrationLog10 pfu/cell
In-vitro result75 % cell death at CI 0.249
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis, activation of caspase 3
Immunogenic effectNA
Clinical trialNA
PMID19594950