Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 53. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1799	Parovirus	H-1PV	DNA	Paroviridae	None	Yes	No	No	ATCC	Human neuroblastoma cell line	WAC-2	7.6E+3 cells per well	NA	MTT assay	50 MOI	1% cell survival	No	No	NA	No response	NA	Cell cycle arrest at G2 phase and induction of apoptosis by virus	NA	NA	20087864
OV_1942	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.0005 MOI	100% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1945	Parovirus	wild type	DNA	Paroviridae	None	No	Parovirus in combination with NDV	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.005 MOI	100% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1948	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.005 MOI	90% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1951	Parovirus	wild type	DNA	Paroviridae	None	No	Parovirus in combination with NDV	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.05 MOI	90% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1954	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.05 MOI	30% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1957	Parovirus	wild type	DNA	Paroviridae	None	No	Parovirus in combination with NDV	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.5 MOI	50% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1960	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	0.5 MOI	10% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1963	Parovirus	wild type	DNA	Paroviridae	None	No	Parovirus in combination with NDV	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	2.5 MOI	50% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1966	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	2.5 MOI	2% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1971	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	5 MOI	22% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1974	Parovirus	wild type	DNA	Paroviridae	None	No	Parovirus in combination with NDV	No	ATCC	Human glioma cell line	U87	NA	NA	MTT assay	5 MOI	40% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1977	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.0005 MOI	100% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1980	Parovirus	wild type	DNA	Paroviridae	None	No	Parovirus in combination with NDV	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.0005 MOI	100% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1983	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.005 MOI	97% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1986	Parovirus	wild type	DNA	Paroviridae	None	No	Parovirus in combination with NDV	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.005 MOI	98% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1989	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.05 MOI	90% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1992	Parovirus	wild type	DNA	Paroviridae	None	No	Parovirus in combination with NDV	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.05 MOI	90% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1995	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.5 MOI	70% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_1998	Parovirus	wild type	DNA	Paroviridae	None	No	Parovirus in combination with NDV	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	0.5 MOI	50% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_2001	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	2.5 MOI	45% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_2004	Parovirus	wild type	DNA	Paroviridae	None	No	Parovirus in combination with NDV	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	2.5 MOI	58% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_2007	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	5 MOI	42% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_2010	Parovirus	wild type	DNA	Paroviridae	None	No	Parovirus in combination with NDV	No	ATCC	Human glioma cell line	U373	NA	NA	MTT assay	5 MOI	52% cell survival	No	No	NA	No response	NA	Virus alone and in combination enhance apoptosis	NA	NA	21607667
OV_5229	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for 4T1 (1.0E+5 cells)	NA	NA	Reduction in tumor volume 700 cubic mm compared to control 1700 cubic mm after 33 days	Intratumoral	Induction of apoptosis	Increase production of IFN-gama and IL-2	NA	27776794
OV_5230	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for 4T1 (1.0E+5 cells)	NA	NA	Reduction in tumor volume 4200 cubic mm compared to control 1700 cubic mm after 33 days	Intratumoral	Induction of apoptosis	Increase production of IFN-gama and IL-2	NA	27776794
OV_5231	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H2052	5.0E+3 cells per well	NA	MTS assay	10 VP per cell	90% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5232	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H2052	5.0E+3 cells per well	NA	MTS assay	100 VP per cell	80% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5233	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H2052	5.0E+3 cells per well	NA	MTS assay	1000 VP per cell	80% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5234	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human mesothelioma cell line	NCIH2452	5.0E+3 cells per well	NA	MTS assay	10 VP per cell	90% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5235	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human mesothelioma cell line	NCIH2452	5.0E+3 cells per well	NA	MTS assay	100 VP per cell	90% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5236	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human mesothelioma cell line	NCIH2452	5.0E+3 cells per well	NA	MTS assay	1000 VP per cell	20% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5237	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H226	5.0E+3 cells per well	NA	MTS assay	10 VP per cell	10% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5238	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H226	5.0E+3 cells per well	NA	MTS assay	100 VP per cell	2% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5239	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H226	5.0E+3 cells per well	NA	MTS assay	1000 VP per cell	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5240	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H28	5.0E+3 cells per well	NA	MTS assay	10 VP per cell	90% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5241	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H28	5.0E+3 cells per well	NA	MTS assay	100 VP per cell	10% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5242	Parovirus	wild type	DNA	Paroviridae	None	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H28	5.0E+3 cells per well	NA	MTS assay	1000 VP per cell	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5243	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H2052	5.0E+3 cells per well	NA	MTS assay	10 VP per cell	90% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5244	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H2052	5.0E+3 cells per well	NA	MTS assay	100 VP per cell	90% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5245	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H2052	5.0E+3 cells per well	NA	MTS assay	1000 VP per cell	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5246	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	ATCC	Human mesothelioma cell line	NCIH2452	5.0E+3 cells per well	NA	MTS assay	10 VP per cell	80% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5247	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	ATCC	Human mesothelioma cell line	NCIH2452	5.0E+3 cells per well	NA	MTS assay	100 VP per cell	10% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5248	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	ATCC	Human mesothelioma cell line	NCIH2452	5.0E+3 cells per well	NA	MTS assay	1000 VP per cell	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5249	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H226	5.0E+3 cells per well	NA	MTS assay	10 VP per cell	10% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5250	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H226	5.0E+3 cells per well	NA	MTS assay	100 VP per cell	5 % cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5251	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H226	5.0E+3 cells per well	NA	MTS assay	1000 VP per cell	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5252	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H28	5.0E+3 cells per well	NA	MTS assay	10 VP per cell	50% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5253	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H28	5.0E+3 cells per well	NA	MTS assay	100 VP per cell	5% cell viable	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5254	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	ATCC	Human mesothelioma cell line	NCI-H28	5.0E+3 cells per well	NA	MTS assay	1000 VP per cell	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	27783867
OV_5255	Parovirus	Ad5/3VEGFE1-delta	DNA	Paroviridae	Deletion mutant for E1A gene and expressing VEGF gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Nude mice xenograft for NCI-H226 cell line (1.0E+7)	1.0E+8 pfu	NA	Improvement in survival time was observed	Intratumoral	NA	NA	NA	27783867
OV_5883	Parovirus	Mutant	DNA	Paroviridae	Deletion mutatnt for Gamma 34.5, ICP6 and ICP47 gene	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Balb/c mice xenograft for PANC-1	1 RU per ml	NA	Tumor volume reduced to 500mm after 83 days	Intratumoral	NA	NA	NA	US8916176
OV_5884	Parovirus	Mutant	DNA	Paroviridae	Deletion mutatnt for Gamma 34.5, ICP6 and ICP47 gene	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Balb/c mice xenograft for HeLa (2.0E+6)	1 RU per ml	NA	Survival time increased up to 40 days	Intratumoral	NA	NA	NA	US8916176

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