Detailed description page of Selected OV_ID


OV_5243 details
Primary information
OV_IDOV_5243
Virus Name Parovirus
StrainAd5/3VEGFE1-delta
Virus typeDNA
Virus familyParoviridae
Modification in virus genomeDeletion mutant for E1A gene and expressing VEGF gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman mesothelioma cell line
Cell lineNCI-H2052
Concentration of cell line5
In-vitro toxicityNA
AssayMTS assay
In-vitro virus concentration10 VP per cell
In-vitro result90% cell viable
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID27783867