| Primary information |
|---|
| OV_ID | OV_5243 |
| Virus Name | Parovirus |
| Strain | Ad5/3VEGFE1-delta |
| Virus type | DNA |
| Virus family | Paroviridae |
| Modification in virus genome | Deletion mutant for E1A gene and expressing VEGF gene |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Human mesothelioma cell line |
| Cell line | NCI-H2052 |
| Concentration of cell line | 5 |
| In-vitro toxicity | NA |
| Assay | MTS assay |
| In-vitro virus concentration | 10 VP per cell |
| In-vitro result | 90% cell viable |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | NA |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 27783867 |