Detailed description page of Selected OV_ID


OV_5255 details
Primary information
OV_IDOV_5255
Virus Name Parovirus
StrainAd5/3VEGFE1-delta
Virus typeDNA
Virus familyParoviridae
Modification in virus genomeDeletion mutant for E1A gene and expressing VEGF gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismNude mice xenograft for NCI-H226 cell line (1 × 10⁷)
In-vivo virus concentration1 × 10⁸ pfu
In-vivo toxicityNA
In-vivo resultImprovement in survival time was observed
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID27783867