Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 92. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_1097AdenovirusZD55-IL-24DNAAdenoviridaeAdenovirus expressing ZD55 gene and IL-24 geneYesNoExpressing IL-24 geneShanghai cell collectionHuman cervical carcinoma cell lineSW6202.0E+6 cells per wellNAMTT assay5 MOINo cell killing after 80 hoursNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15661558
OV_1098AdenovirusAd-IL-24DNAAdenoviridaeAdenovirus expressing IL-24 geneYesNoExpressing IL-24 geneShanghai cell collectionHuman cervical carcinoma cell lineSW6202.0E+6 cells per wellNAMTT assay5 MOINo cell killing after 80 hoursNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15661558
OV_1099AdenovirusZD55-EGFPDNAAdenoviridaeAdenovirus expressing EGFP geneYesNoNoShanghai cell collectionHuman cervical carcinoma cell lineSW6202.0E+6 cells per wellNAMTT assay5 MOINo cell killing after 80 hoursNoNoNA No responseNAApoptosis induction and cspase 3 activationNANA15661558
OV_1150Herpes simplex virusNV1020DNAHerpesviridaeNoneYesNoNoATCCColon carcinoma cell lineSW6201.0E+4 cells per wellNAWST-1 assay1 × 10⁶ pfu/ml80% cell killingNoNoNA No responseNANANANA17117895
OV_2073AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANACrystal violet staining0.1 MOINo cell death observedNoNoNA No responseNAInduction of senescenceNANA21794078
OV_2074AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANACrystal violet staining1 MOISome cell death observedNoNoNA No responseNAInduction of senescenceNANA21794078
OV_2075AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANACrystal violet staining10 MOIAll cells was deadNoNoNA No responseNAInduction of senescenceNANA21794078
OV_2076AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANACrystal violet staining100 MOIAll cells was deadNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2089AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANAMTT assay1 MOIAbsorbance decrease to below 0.1 after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2090AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANAMTT assay1 MOIAbsorbance decrease to below 0.1 after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2091AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANAMTT assay1 MOIAbsorbance decrease to below 0.1 after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2092AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANAMTT assay1 MOIAbsorbance decrease to below 0.1 after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2093AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman colon cancer cell lineSW620NANANANANABALB/c nude mice xenograft for SW620 cell line (5.0E+6 cells)2.0E+9 pfuNA Reduction in tumor volume below 100 mm after 9 weeksNAInduction of apoptosisNANA21794078
OV_2102AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of AFP geneYesNoVirus expressing IL-24 geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining0.1 MOINo cell killingNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2103AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of AFP geneYesNoVirus expressing IL-24 geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining1 MOINo cell killingNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2104AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of AFP geneYesNoVirus expressing IL-24 geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining10 MOINo cell killingNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2105AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of AFP geneYesNoVirus expressing IL-24 geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining100 MOINo cell killingNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2122AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of TRAIL geneYesNoVirus expressing TRAIL geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining0.1 MOISome cell death observedNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2123AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of TRAIL geneYesNoVirus expressing TRAIL geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining1 MOISome cell death observedNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2124AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of TRAIL geneYesNoVirus expressing TRAIL geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining10 MOISome cell death observedNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2125AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of TRAIL geneYesNoVirus expressing TRAIL geneATCCHuman colon cancer cell lineSW620NANACrystal violet staining100 MOISome cell death observedNoNoNA No responseNAInduction of apoptosis in cancer as measured by TUNEL assayNANA21979578
OV_2159EnterovirusEnterovirus B species echovirus 12RNAPicornaviridaeNoneYesNoNoATCCColon cancer cell lineSW620NANAMicroscopy examination1 MOIComplete cell death after 3 daysNoNoNA No responseNAVirus can cause induction in apoptosisNANA21999585
OV_2160EnterovirusEnterovirus B species echovirus 15RNAPicornaviridaeNoneYesNoNoATCCColon cancer cell lineSW620NANAMicroscopy examination1 MOIComplete cell death after 5 daysNoNoNA No responseNAVirus can cause induction in apoptosisNANA21999585
OV_2161EnterovirusEnterovirus B species echovirus 17RNAPicornaviridaeNoneYesNoNoATCCColon cancer cell lineSW620NANAMicroscopy examination1 MOIComplete cell death after 7 daysNoNoNA No responseNAVirus can cause induction in apoptosisNANA21999585
OV_2162EnterovirusEnterovirus B species echovirus 26RNAPicornaviridaeNoneYesNoNoATCCColon cancer cell lineSW620NANAMicroscopy examination1 MOIComplete cell death after 7 daysNoNoNA No responseNAVirus can cause induction in apoptosisNANA21999585
OV_2163EnterovirusEnterovirus B species echovirus 29RNAPicornaviridaeNoneYesNoNoATCCColon cancer cell lineSW620NANAMicroscopy examination1 MOIComplete cell death after 7 daysNoNoNA No responseNAVirus can cause induction in apoptosisNANA21999585
OV_2756AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW620NANAMTT assay0.01 MOINo cell deathNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2757AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW620NANAMTT assay0.5 MOIModerate cell deathNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2758AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW620NANAMTT assay1 MOIMost of the cells are diedNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2759AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW620NANAMTT assay10 MOIAll cells are diedNoNoNA No responseNAInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2768AdenovirusZD55-lipocalin2DNAAdenoviridaeDeletion of E1B55 gene and insertion of lipocalin2 geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW620NANANANANAnude mice xenograft for Sw620 (1.5E+7 cells)5.0E+8 pfuNA Reduction in tumor volume below 500 as comapred to control 1500mm and increase in median survival timeIntratumoralInducing apoptosis and decreasing microvessel density of tumorNANA23464854
OV_2822Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineSW6201.0E+6 cells per wellNAMTT assay0.1 MOI100% cell survival after 24 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2823Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineSW6201.0E+6 cells per wellNAMTT assay0.1 MOI90% cell survival after 48 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2824Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineSW6201.0E+6 cells per wellNAMTT assay0.1 MOI50% cell survival after 72 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2837Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineSW6201.0E+6 cells per wellNAMTT assay1 MOI80% cell survival after 24 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2838Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineSW6201.0E+6 cells per wellNAMTT assay1 MOI40% cell survival after 48 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2839Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineSW6201.0E+6 cells per wellNAMTT assay1 MOI100% cell death after 72 hoursNoNoNA No responseNANAUpregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3NA23531320
OV_2851Measles virusAttenuated strainRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureHuman colorectal cancer cell lineSW6201 million cells per wellNACell death detection kit1 MOI30% cells survivedNoNoNA No responseNAActivation of caspase-3NANA23586034
OV_3141Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay5 MOI50% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3142Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI25% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3143Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay20 MOI18% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3147Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI90% cell viability after day 1NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3148Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI60% cell viability after day 2NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3149Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI40% cell viability after day 3NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3150Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI10% cell viability after day 4NoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3155Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneYesNoNoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW620NANANANANAMouse model xenograft for SW620 (1.0E+6)5.0E+8 pfuNA Reduction in tumor volume below 200mm as compared to control 2500mm after 24 daysIntratumoralCaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3157Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (5nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay5 MOI60% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3158Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (10nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay10 MOI50% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3159Herpes simplex virusSPDD-UGDNAAdenoviridaeVirus expressing SNORD44 gene and GAS5 geneNoVirus in combination with rapamycin (20nM)NoCell bank of type culture collection of chinese academy of scienceHuman colon carcinoma cell lineSW6202000 cells per wellNACCK-8 assay20 MOI40% cell viabilityNoNoNA No responseNACaspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell lineNANA28530127
OV_3298Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 81.1% as compared to control 100% after day 3IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3299Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 89.7% as compared to control 100% after day 5IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3300Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 80.7% as compared to control 100% after day 8IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3301Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 71.9% as compared to control 100% after day 10IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3302Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 68.1% as compared to control 100% after day 12IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3303Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 58.4% as compared to control 100% after day 15IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3304Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 57.1% as compared to control 100% after day 17IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3305Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 58.3% as compared to control 100% after day 19IntratumoralInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3306Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 67.8% as compared to control 100% after day 3IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3307Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 60.8% as compared to control 100% after day 5IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3308Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 62.4% as compared to control 100% after day 8IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3309Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 64.7% as compared to control 100% after day 10IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3310Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 64.4% as compared to control 100% after day 12IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3311Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 61.5% as compared to control 100% after day 15IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3312Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 59.7% as compared to control 100% after day 17IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3313Newcastle disease virusR2B mukteshwar strainRNAParamyxoviridaeNoneYesNoNoNAHuman colon cancer cell lineSW620NANANANANABalb/c nude mice xenograft for SW-620 cell line (1.0E+6)1.0E+7 pfuNA Tumor volume become 59.9% as compared to control 100% after day 19IntravenousInduction of necrosis and apoptosis in animal model cancer cell lineNANA28578522
OV_3546AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay5 MOI98% cell viability after 24 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3547AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay5 MOI90% cell viability after 48 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3548AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay5 MOI70% cell viability after 72 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3549AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay5 MOI45% cell viability after 96 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3550AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay10 MOI98% cell viability after 24 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3551AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay10 MOI90% cell viability after 48 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3552AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay10 MOI50% cell viability after 72 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3553AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay10 MOI25% cell viability after 96 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3554AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay15 MOI95% cell viability after 24 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3555AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay15 MOI80% cell viability after 48 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3556AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay15 MOI40% cell viability after 72 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3557AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneYesNoNoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay15 MOI20% cell viability after 96 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3558AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneNoVirus in combination with luteolin (25 micromolar)NoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay5 MOI60% cell viability after 24 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3559AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneNoVirus in combination with luteolin (25 micromolar)NoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay5 MOI18% cell viability after 48 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3560AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneNoVirus in combination with luteolin (25 micromolar)NoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay5 MOI17% cell viability after 72 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3561AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneNoVirus in combination with luteolin (25 micromolar)NoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay5 MOIComplete cell death after 96 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3562AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneNoVirus in combination with luteolin (25 micromolar)NoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay10 MOI58% cell viability after 24 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3563AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneNoVirus in combination with luteolin (25 micromolar)NoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay10 MOI16% cell viability after 48 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3564AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneNoVirus in combination with luteolin (25 micromolar)NoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay10 MOI5% cell viability after 72 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3565AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneNoVirus in combination with luteolin (25 micromolar)NoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay10 MOIComplete cell death after 96 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3566AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneNoVirus in combination with luteolin (25 micromolar)NoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay15 MOI58% cell viability after 24 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3567AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneNoVirus in combination with luteolin (25 micromolar)NoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay15 MOI16% cell viability after 48 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3568AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneNoVirus in combination with luteolin (25 micromolar)NoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay15 MOI5% cell viability after 72 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_3569AdenovirusAdenovirus CD55-TRAILDNAAdenoviridaeVirus expressingTRAIL geneNoVirus in combination with luteolin (25 micromolar)NoShanghai cell collectionHuman colorectal cancer cell lineSW6205000 cells per wellNAMTT assay15 MOIComplete cell death after 96 hoursNoNoNA No responseNAVirus in combination with induce apiptosis in cancer cellNANA29039580
OV_4291AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman colorectal adenocarcinomaSW6204000 cells per wellNAMTT assay10 pfu43.7 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_5624Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman colon carcinoma cell lineSW62080% confluencyNAMTT assay55 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5844Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman colon carcinoma cell lineSW62080% confluencyNANA55 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578