Detailed description page of Selected OV_ID


OV_3300 details
Primary information
OV_IDOV_3300
Virus Name Newcastle disease virus
StrainR2B mukteshwar strain
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineHuman colon cancer cell line
Cell lineSW620
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBalb/c nude mice xenograft for SW-620 cell line (1 × 10⁶)
In-vivo virus concentration1 × 10⁷ pfu
In-vivo toxicityNA
In-vivo resultTumor volume become 80.7% as compared to control 100% after day 8
Mode of deliveryIntratumoral
Pathway inductionInduction of necrosis and apoptosis in animal model cancer cell line
Immunogenic effectNA
Clinical trialNA
PMID28578522