Detailed description page of Selected OV_ID


OV_3546 details
Primary information
OV_IDOV_3546
Virus Name Adenovirus
StrainAdenovirus CD55-TRAIL
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeVirus expressingTRAIL gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineShanghai cell collection
Origin of cell lineHuman colorectal cancer cell line
Cell lineSW620
Concentration of cell line5000
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration5 MOI
In-vitro result98% cell viability after 24 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus in combination with induce apiptosis in cancer cell
Immunogenic effectNA
Clinical trialNA
PMID29039580