Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 30. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_2055	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	0.1 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2056	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	0.1 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2057	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	0.1 MOI	30% cell survival after 72 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2058	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	0.1 MOI	30% cell survival after 96 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2059	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	1 MOI	80% cell survival after 24 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2060	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	1 MOI	30% cell survival after 48 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2061	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	1 MOI	20% cell survival after 72 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2062	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	1 MOI	20% cell survival after 96 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2063	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	NA	NA	NA	Athymic hsd nude mice xenograft for PLC cell line	5.0E+6 pfu	Reduction in tumor volume below 2000mm compared to control after 45 days	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2534	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	0.1 MOI	100% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2535	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	1 MOI	90% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2536	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	30% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2545	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	100% cells viable after day 1	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2546	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	80% cells viable after day 2	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2547	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	40% cells viable after day 3	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2548	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	10% cells viable after day 4	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2591	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	PLC	5.0E+4 cells per well	NA	MTT assay	10 MOI	10% cells are viable after 4 days	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2597	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	PLC	5.0E+4 cells per well	NA	Crystal violet staining	0.1 MOI	100% cells viavility	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2598	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	PLC	5.0E+4 cells per well	NA	Crystal violet staining	1 MOI	Some cells are viable	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2599	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	PLC	5.0E+4 cells per well	NA	Crystal violet staining	10 MOI	100% cell death	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2600	Adenovirus	Ad.enAFP-E1A-delta-E1B-IL-24	DNA	Adenoviridae	Deletion of E1A, E1B and addition of AFP and IL-24	Yes	No	Virus expressing IL-24 gene	ATCC	Human liver cancer cell line	PLC	5.0E+4 cells per well	NA	Crystal violet staining	100 MOI	100% cell death	No	No	NA	No response	NA	Induction of apoptosis in cancer	Upregulation of GADD34	NA	22790965
OV_2731	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	100% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2732	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	90% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2733	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2734	Adenovirus	AdCN205	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	50% cell viability after 96 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2735	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	90% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2736	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2737	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	50% cell viability after 72 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_2738	Adenovirus	AdCN205	DNA	Adenoviridae	None	No	Virus strain in combination with miR-34-a	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	PLC5	1.0E+4 cells per well	NA	MTT assay	5 MOI	30% cell viability after 96 hours	No	No	NA	No response	NA	Induction of apoptosis, G1 arrest and sensescence	Inhibition of oncogene and antiapototic gene	NA	23292172
OV_4312	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human hepatoma	PLC	4000 cells per well	NA	MTT assay	10 pfu	80.5 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347