The total number of records retrieved from this search are 84. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_862	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	1 MOI	80 % cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_865	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	1 MOI	96% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_868	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	0.1 MOI	60 % cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_871	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	0.1 MOI	80% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_874	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	1 MOI	85 % cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_877	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	1 MOI	97% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_880	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	0.1 MOI	60 % cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_883	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	0.1 MOI	88% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_1094	Adenovirus	ZD55-IL-24	DNA	Adenoviridae	Adenovirus expressing ZD55 gene and IL-24 gene	Yes	No	Expressing IL-24 gene	Shanghai cell collection	Human cervical carcinoma cell line	HT-29	2.0E+6 cells per well	NA	MTT assay	5 MOI	60% cell killing after 80 hours	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1095	Adenovirus	Ad-IL-24	DNA	Adenoviridae	Adenovirus expressing IL-24 gene	Yes	No	Expressing IL-24 gene	Shanghai cell collection	Human cervical carcinoma cell line	HT-29	2.0E+6 cells per well	NA	MTT assay	5 MOI	20% cell killing after 80 hours	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1096	Adenovirus	ZD55-EGFP	DNA	Adenoviridae	Adenovirus expressing EGFP gene	Yes	No	No	Shanghai cell collection	Human cervical carcinoma cell line	HT-29	2.0E+6 cells per well	NA	MTT assay	5 MOI	40% cell killing after 80 hours	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15661558
OV_1155	Herpes simplex virus	NV1020	DNA	Herpesviridae	None	Yes	No	No	ATCC	Colon carcinoma cell line	HT-29	2.5E+3 cells per well	NA	WST-1 assay	1 × 10⁶ pfu/ml	80% cell killing	No	No	NA	No response	NA	NA	NA	NA	17117895
OV_1158	Herpes simplex virus	NV1020	DNA	Herpesviridae	None	No	Virus strain in combination with 5-FU	No	ATCC	Colon carcinoma cell line	HT-29	1.0E+3 cells per well	NA	WST-1 assay	1 × 10⁶ pfu/ml	Complete reduction in tumor,shows synergism with drug	No	No	NA	No response	NA	NA	NA	NA	17117895
OV_1159	Herpes simplex virus	NV1020	DNA	Herpesviridae	None	No	Virus strain in combination with SN-38	No	ATCC	Colon carcinoma cell line	HT-29	1.0E+3 cells per well	NA	WST-1 assay	1 × 10⁶ pfu/ml	Complete reduction in tumor,shows synergism with drug	No	No	NA	No response	NA	NA	NA	NA	17117895
OV_2144	Enterovirus	Enterovirus B species echovirus 12	RNA	Picornaviridae	None	Yes	No	No	ATCC	Colon cancer cell line	HT-29	NA	NA	Microscopy examination	1 MOI	Complete cell death after 3 days	No	No	NA	No response	NA	Virus can cause induction in apoptosis	NA	NA	21999585
OV_2145	Enterovirus	Enterovirus B species echovirus 15	RNA	Picornaviridae	None	Yes	No	No	ATCC	Colon cancer cell line	HT-29	NA	NA	Microscopy examination	1 MOI	Complete cell death after 3 days	No	No	NA	No response	NA	Virus can cause induction in apoptosis	NA	NA	21999585
OV_2146	Enterovirus	Enterovirus B species echovirus 17	RNA	Picornaviridae	None	Yes	No	No	ATCC	Colon cancer cell line	HT-29	NA	NA	Microscopy examination	1 MOI	Complete cell death after 1 days	No	No	NA	No response	NA	Virus can cause induction in apoptosis	NA	NA	21999585
OV_2147	Enterovirus	Enterovirus B species echovirus 26	RNA	Picornaviridae	None	Yes	No	No	ATCC	Colon cancer cell line	HT-29	NA	NA	Microscopy examination	1 MOI	Complete cell death after 2 days	No	No	NA	No response	NA	Virus can cause induction in apoptosis	NA	NA	21999585
OV_2148	Enterovirus	Enterovirus B species echovirus 29	RNA	Picornaviridae	None	Yes	No	No	ATCC	Colon cancer cell line	HT-29	NA	NA	Microscopy examination	1 MOI	Complete cell death after 2 days	No	No	NA	No response	NA	Virus can cause induction in apoptosis	NA	NA	21999585
OV_2764	Adenovirus	ZD55-lipocalin2	DNA	Adenoviridae	Deletion of E1B55 gene and insertion of lipocalin2 gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	NA	NA	MTT assay	0.01 MOI	No cell death	No	No	NA	No response	NA	Inducing apoptosis and decreasing microvessel density of tumor	NA	NA	23464854
OV_2765	Adenovirus	ZD55-lipocalin2	DNA	Adenoviridae	Deletion of E1B55 gene and insertion of lipocalin2 gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	NA	NA	MTT assay	0.5 MOI	No cell death	No	No	NA	No response	NA	Inducing apoptosis and decreasing microvessel density of tumor	NA	NA	23464854
OV_2766	Adenovirus	ZD55-lipocalin2	DNA	Adenoviridae	Deletion of E1B55 gene and insertion of lipocalin2 gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	NA	NA	MTT assay	1 MOI	No cell death	No	No	NA	No response	NA	Inducing apoptosis and decreasing microvessel density of tumor	NA	NA	23464854
OV_2767	Adenovirus	ZD55-lipocalin2	DNA	Adenoviridae	Deletion of E1B55 gene and insertion of lipocalin2 gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	NA	NA	MTT assay	10 MOI	Moderate cell death	No	No	NA	No response	NA	Inducing apoptosis and decreasing microvessel density of tumor	NA	NA	23464854
OV_2813	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	1.0E+6 cells per well	NA	MTT assay	0.1 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	NA	Upregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3	NA	23531320
OV_2814	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	1.0E+6 cells per well	NA	MTT assay	0.1 MOI	50% cell survival after 48 hours	No	No	NA	No response	NA	NA	Upregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3	NA	23531320
OV_2815	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	1.0E+6 cells per well	NA	MTT assay	0.1 MOI	20% cell survival after 72 hours	No	No	NA	No response	NA	NA	Upregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3	NA	23531320
OV_2828	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	1.0E+6 cells per well	NA	MTT assay	1 MOI	80% cell survival after 24 hours	No	No	NA	No response	NA	NA	Upregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3	NA	23531320
OV_2829	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	1.0E+6 cells per well	NA	MTT assay	1 MOI	25% cell survival after 48 hours	No	No	NA	No response	NA	NA	Upregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3	NA	23531320
OV_2830	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	1.0E+6 cells per well	NA	MTT assay	1 MOI	100% cell death after 72 hours	No	No	NA	No response	NA	NA	Upregulation of immune related antigens and cytokines like IFN-gamma, IP-10, MCP-1, MCP-3	NA	23531320
OV_2849	Measles virus	Attenuated strain	RNA	Paramyxoviridae	None	Yes	No	No	Laboratory grown own culture	Human colorectal cancer cell line	HT-29	1 million cells per well	NA	Cell death detection kit	1 MOI	45% cells survived	No	No	NA	No response	NA	Activation of caspase-3	NA	NA	23586034
OV_2992	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2993	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	98% cell survival after 48 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2994	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	70% cell survival after 72 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2995	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	70% cell survival after 96 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2996	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	0.01 MOI	20% cell survival after 120 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2997	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	80% cell survival after 24 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2998	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	40% cell survival after 48 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_2999	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	20% cell survival after 72 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3000	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	10% cell survival after 96 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3001	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	3.0E+3 cells per well	NA	Cell viability assay kit	1 MOI	100% cell death after 120 hours	No	No	NA	No response	NA	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3003	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	Yes	No	No	ATCC	Human colorectal cancer cell line	HT-29	NA	NA	NA	NA	NA	Hsd:athymic nude mice xenograft for HT-29 (5.0E+6 cells)	1.0E+5 pfu	NA	Tumor volume reached 1500mm after day 50	Intratumoral	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3005	Poxvirus	CF33-hNIS	DNA	Poxviridae	Insertion of gene encoding human hNIS	No	Virus in combination with I-131	No	ATCC	Human colorectal cancer cell line	HT-29	NA	NA	NA	NA	NA	Hsd:athymic nude mice xenograft for HT-29 (3.0E+9 cells)	1.0E+4 pfu	NA	Reduction in tumor volume below 300mm after 45 days	Intravenous	Immunogenicity followed by virus induced cell death	NA	NA	31061881
OV_3594	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	5 MOI	98% cell viability after 24 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3595	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	5 MOI	85% cell viability after 48 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3596	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	5 MOI	98% cell viability after 72 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3597	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	5 MOI	98% cell viability after 96 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3598	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	10 MOI	98% cell viability after 24 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3599	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	10 MOI	70% cell viability after 48 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3600	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	10 MOI	90% cell viability after 72 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3601	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	10 MOI	80% cell viability after 96 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3602	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	15 MOI	98% cell viability after 24 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3603	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	15 MOI	70% cell viability after 48 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3604	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	15 MOI	90% cell viability after 72 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3605	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	Yes	No	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	15 MOI	60% cell viability after 96 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3606	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (25 micromolar)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	5 MOI	70% cell viability after 24 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3607	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (25 micromolar)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	5 MOI	60% cell viability after 48 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3608	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (25 micromolar)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	5 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3609	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (25 micromolar)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	5 MOI	50% cell viability after 96 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3610	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (25 micromolar)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	10 MOI	70% cell viability after 24 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3611	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (25 micromolar)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	10 MOI	60% cell viability after 48 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3612	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (25 micromolar)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	10 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3613	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (25 micromolar)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	10 MOI	50% cell viability after 96 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3614	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (25 micromolar)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	15 MOI	60% cell viability after 24 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3615	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (25 micromolar)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	15 MOI	40% cell viability after 48 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3616	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (25 micromolar)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	15 MOI	40% cell viability after 72 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3617	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (25 micromolar)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	5000 cells per well	NA	MTT assay	15 MOI	22% cell viability after 96 hours	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3618	Adenovirus	Adenovirus CD55-TRAIL	DNA	Adenoviridae	Virus expressingTRAIL gene	No	Virus in combination with luteolin (50mg/kg)	No	Shanghai cell collection	Human colorectal cancer cell line	HT-29	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for HT29 cell line (8.0E+6)	2.0E+9 pfu	NA	Decrease in tumor volume to below 2000mm after 30 days comapred to control 4000mm	Intratumoral	Virus in combination with induce apiptosis in cancer cell	NA	NA	29039580
OV_3673	Measles virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human colon cancer cell line	HT-29	5000 cells per well	NA	MTT assay	1 MOI	70% cell viability after day 3	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3674	Measles virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human colon cancer cell line	HT-29	5000 cells per well	NA	MTT assay	1 MOI	10% cell viability after day 6	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3689	Mumps virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human colon cancer cell line	HT-29	5000 cells per well	NA	MTT assay	1 MOI	80% cell viability after day 3	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3690	Mumps virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human colon cancer cell line	HT-29	5000 cells per well	NA	MTT assay	1 MOI	75% cell viability after day 6	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3705	Measles and mumps virus	wild type	RNA	Paramyxoviridae	None	No	Measles virus in combination with mumps virus	No	ATCC	Human colon cancer cell line	HT-29	5000 cells per well	NA	MTT assay	1 MOI	70% cell viability after day 3	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3706	Measles and mumps virus	wild type	RNA	Paramyxoviridae	None	No	Measles virus in combination with mumps virus	No	ATCC	Human colon cancer cell line	HT-29	5000 cells per well	NA	MTT assay	1 MOI	Complete cell death after day 6	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_4407	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human colon carcinoma	HT-29	NA	NA	Statistical method	26.80+/- 7.82	20% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4408	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human colon carcinoma	HT-29	NA	NA	Statistical method	74.23+/- 18.19	50% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4409	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human colon carcinoma	HT-29	NA	NA	Statistical method	127.2+/- 39	70% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4410	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human colon carcinoma	HT-29/CP-5c	NA	NA	Statistical method	7.56+/- 1.96	20% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4411	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human colon carcinoma	HT-29/CP-5c	NA	NA	Statistical method	26.70+/- 5.90	50% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4412	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human colon carcinoma	HT-29/CP-5c	NA	NA	Statistical method	49.95+/- 9.01	70% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4413	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human colon carcinoma	HT-29/carbo-15d-1	NA	NA	Statistical method	20.13+/- 10.23	20% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4414	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human colon carcinoma	HT-29/carbo-15d-1	NA	NA	Statistical method	48.46+/- 19.03	50% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_4415	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human colon carcinoma	HT-29/carbo-15d-1	NA	NA	Statistical method	78.27+/- 25.11	70% cancer cell death	No	No	NA	No response	NA	Increase in apoptosis upto 25%	NA	NA	26429639
OV_5625	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human colon carcinoma cell line	HT-29	80% confluency	NA	MTT assay	1 ×10⁶ pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5845	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human colon carcinoma cell line	HT-29	80% confluency	NA	NA	1 ×10⁶ pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578