Primary information |
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OV_ID | OV_4413 |
Virus Name | Adenovirus |
Strain | ONYX-015 |
Virus type | DNA |
Virus family | Adenoviridae |
Modification in virus genome | None |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | ATCC |
Origin of cell line | Human colon carcinoma |
Cell line | HT-29/carbo-15d-1 |
Concentration of cell line | 0 |
In-vitro toxicity | NA |
Assay | Statistical method |
In-vitro virus concentration | 20.13+/- 10.23 |
In-vitro result | 20% cancer cell death |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | Increase in apoptosis upto 25% |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 26429639 |