Primary information |
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OV_ID | OV_3598 |
Virus Name | Adenovirus |
Strain | Adenovirus CD55-TRAIL |
Virus type | DNA |
Virus family | Adenoviridae |
Modification in virus genome | Virus expressingTRAIL gene |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | Shanghai cell collection |
Origin of cell line | Human colorectal cancer cell line |
Cell line | HT-29 |
Concentration of cell line | 5000 |
In-vitro toxicity | NA |
Assay | MTT assay |
In-vitro virus concentration | 10 MOI |
In-vitro result | 98% cell viability after 24 hours |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | Virus in combination with induce apiptosis in cancer cell |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 29039580 |