The total number record retrieved from this search are 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_133	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	1% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_134	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	1% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_135	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	25% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_136	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	16% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_137	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	1% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_138	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	5% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_139	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	20% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_140	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	32% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_141	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	3% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_142	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	10% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_143	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	30% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_144	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	32% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_145	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	15% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_146	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	10% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_147	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	33% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_148	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	51% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_149	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	20% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_150	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	26% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_151	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	49% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_152	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	98% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_153	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	25% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_154	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	40% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_155	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	54% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_156	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	58% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_157	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	28% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_158	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	45% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_159	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_160	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	58% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_161	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	30% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_162	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	40% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_163	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 2 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_164	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with tubacin - 5 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	70% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_165	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁷ MOI	5% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_166	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁷ MOI	10% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_167	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁷ MOI	10% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_168	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	9% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_169	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	6% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_170	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁶ MOI	3% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_171	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	15% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_172	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	10% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_173	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁵ MOI	5% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_174	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	40% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_175	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	44% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_176	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻⁴ MOI	43% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_177	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	49% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_178	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	46% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_179	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻³ MOI	42% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_180	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	51% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_181	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_182	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻² MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_183	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	51% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_184	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_185	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3⁻¹ MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_186	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	51% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_187	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_188	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	1 MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_189	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	Yes	No	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	54% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_190	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 1 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	52% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_191	Herpes simplex virus	rQNestin34.5	DNA	Herpesviridae	Deletion mutant for both copies of gamma 34.5 gene and ICP6 gene, re-addition of 34.5 gene under nestin promoter	No	Virus in combination with CI994 - 3 micromolar starting at 14 hours before infection	No	NA	Human glioblastoma astrocytoma cell line	U251	NA	NA	LDH cytotoxicity assay	3 MOI	60% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26524593
OV_323	Canine parvovirus	CPV2.NS1	DNA	Paroviridae	CPV genome expressing non-structural protein (NS1)	Yes	No	No	NCCS (National Centre for Cell Science, Pune, India)	Human cervical cancer cell line	HeLa	density of E+4 to E+5 cells/well in 120 microlitres of culture medium	NA	LDH assay	NA	9% cancer cell death at 24 hours	No	No	NA	No response	NA	Apoptosis is induced via mitochondrial depolarization, release of cytochrome-c and activation of caspase 9	NA	NA	26555166
OV_324	Canine parvovirus	CPV2.NS1	DNA	Paroviridae	CPV genome expressing non-structural protein (NS1)	Yes	No	No	NCCS (National Centre for Cell Science, Pune, India)	Human cervical cancer cell line	HeLa	density of E+4 to E+5 cells/well in 120 microlitres of culture medium	NA	LDH assay	NA	18% cancer cell death at 48 hours	No	No	NA	No response	NA	Apoptosis is induced via mitochondrial depolarization, release of cytochrome-c and activation of caspase 9	NA	NA	26555166
OV_1842	Herpes simplex virus	NV1023	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	Hs766T	2.0E+4 cells per well	NA	LDH release assay	0.01 MOI	100% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1843	Herpes simplex virus	NV1024	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	Hs766T	2.0E+4 cells per well	NA	LDH release assay	0.01 MOI	100% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1844	Herpes simplex virus	NV1025	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	Hs766T	2.0E+4 cells per well	NA	LDH release assay	0.01 MOI	80% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1845	Herpes simplex virus	NV1026	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	Hs766T	2.0E+4 cells per well	NA	LDH release assay	0.01 MOI	70% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1846	Herpes simplex virus	NV1027	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	Hs766T	2.0E+4 cells per well	NA	LDH release assay	0.1 MOI	90% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1847	Herpes simplex virus	NV1028	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	Hs766T	2.0E+4 cells per well	NA	LDH release assay	0.1 MOI	90% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1848	Herpes simplex virus	NV1029	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	Hs766T	2.0E+4 cells per well	NA	LDH release assay	0.1 MOI	80% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1849	Herpes simplex virus	NV1030	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	Hs766T	2.0E+4 cells per well	NA	LDH release assay	0.1 MOI	60% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1850	Herpes simplex virus	NV1031	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	Hs766T	2.0E+4 cells per well	NA	LDH release assay	1 MOI	70% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1851	Herpes simplex virus	NV1032	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	Hs766T	2.0E+4 cells per well	NA	LDH release assay	1 MOI	65% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1852	Herpes simplex virus	NV1033	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	Hs766T	2.0E+4 cells per well	NA	LDH release assay	1 MOI	50% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1853	Herpes simplex virus	NV1034	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	Hs766T	2.0E+4 cells per well	NA	LDH release assay	1 MOI	20% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1854	Herpes simplex virus	NV1035	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.1 MOI	No cell killing after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1855	Herpes simplex virus	NV1036	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.1 MOI	No cell killing after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1856	Herpes simplex virus	NV1037	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.1 MOI	No cell killing after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1857	Herpes simplex virus	NV1038	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.1 MOI	No cell killing after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1858	Herpes simplex virus	NV1039	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.2 MOI	No cell killing after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1859	Herpes simplex virus	NV1040	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.2 MOI	No cell killing after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1860	Herpes simplex virus	NV1041	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.2 MOI	98% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1861	Herpes simplex virus	NV1042	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.2 MOI	No cell killing after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1862	Herpes simplex virus	NV1043	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.4 MOI	No cell killing after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1863	Herpes simplex virus	NV1044	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.4 MOI	No cell killing after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1864	Herpes simplex virus	NV1045	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.4 MOI	No cell killing after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1865	Herpes simplex virus	NV1046	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.4 MOI	No cell killing after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1866	Herpes simplex virus	NV1047	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.8 MOI	No cell killing after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1867	Herpes simplex virus	NV1048	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.8 MOI	No cell killing after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1868	Herpes simplex virus	NV1049	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.8 MOI	No cell killing after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1869	Herpes simplex virus	NV1050	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	0.8 MOI	90% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1870	Herpes simplex virus	NV1051	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	1.6 MOI	No cell killing after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1871	Herpes simplex virus	NV1052	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	1.6 MOI	90% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1872	Herpes simplex virus	NV1053	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	1.6 MOI	90% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1873	Herpes simplex virus	NV1054	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	1.6 MOI	80% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1874	Herpes simplex virus	NV1055	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	3.2 MOI	No cell killing after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1875	Herpes simplex virus	NV1056	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	3.2 MOI	90% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1876	Herpes simplex virus	NV1057	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	3.2 MOI	80% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1877	Herpes simplex virus	NV1058	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	2.0E+4 cells per well	NA	LDH release assay	3.2 MOI	80% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1878	Herpes simplex virus	NV1059	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.012 MOI	90% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1879	Herpes simplex virus	NV1060	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.012 MOI	90% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009
OV_1880	Herpes simplex virus	NV1061	DNA	Herpesviridae	Insertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 gene	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	2.0E+4 cells per well	NA	LDH release assay	0.012 MOI	90% cell survival after day 5	No	No	NA	No response	NA	Induction of apoptosis by the virus	NA	NA	20629009