| Primary information |
|---|
| OV_ID | OV_324 |
| Virus Name | Canine parvovirus |
| Strain | CPV2.NS1 |
| Virus type | DNA |
| Virus family | Paroviridae |
| Modification in virus genome | CPV genome expressing non-structural protein (NS1) |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | NCCS (National Centre for Cell Science, Pune, India) |
| Origin of cell line | Human cervical cancer cell line |
| Cell line | HeLa |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | LDH assay |
| In-vitro virus concentration | NA |
| In-vitro result | 18% cancer cell death at 48 hours |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Apoptosis is induced via mitochondrial depolarization, release of cytochrome-c and activation of caspase 9 |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 26555166 |