Detailed description page of Selected OV_ID


OV_324 details
Primary information
OV_IDOV_324
Virus Name Canine parvovirus
StrainCPV2.NS1
Virus typeDNA
Virus familyParoviridae
Modification in virus genomeCPV genome expressing non-structural protein (NS1)
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNCCS (National Centre for Cell Science, Pune, India)
Origin of cell lineHuman cervical cancer cell line
Cell lineHeLa
Concentration of cell line0
In-vitro toxicityNA
AssayLDH assay
In-vitro virus concentrationNA
In-vitro result18% cancer cell death at 48 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionApoptosis is induced via mitochondrial depolarization, release of cytochrome-c and activation of caspase 9
Immunogenic effectNA
Clinical trialNA
PMID26555166