| Compound | 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone |
| NPACT-Id | NPACT00064 |
| IUPAC | (E)-1-(2,4-dihydroxy-6-methoxy-3,5-dimethylphenyl)-3-phenylprop-2-en-1-one |
| Synonyms | Aurentiacin-A; 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone |
| PubChem Id | 10424762 |
| Class | Flavonoid |
| In-vitro anticancer activity | 6 cancer cell lines |
| In-Vivo anticancer activity | No |
| Targets | AKT1 | BCL2 | BCL2L11 | ERBB2 | KDR | MAPK1 | All | |
| Properties | Physical Elemental Topological |
| InChi Key | TZEQDSMFACWASC-MDZDMXLPSA-N |
| InChi | 1S/C18H18O4/c1-11-16(20)12(2)18(22-3)15(17(11)21)14(19)10-9-13-7-5-4-6-8-13/h4-10,20-21H,1-3H3/b10-9+ |
| SMILES | O(c1c(c(O)c(c(O)c1C(=O)/C=C/c1ccccc1)C)C)C |
|
SMART | [H]OC1=C(C(=O)C([H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C(C(O[H])=C1C([H])([H])[H])C([H])([H])[H] |
| CAS No. | - |
|
Structure
Download | 
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| Cross Refrence in other databases |
| Super Natural | - |
| CTD | C501649 |
| HIT | - |
| NCI-60 GI50 data | - |
| Suppliers | Ambinter, ZINC, |
| Drug-Likeliness Filters | Lipinski's rule of five | Yes |
| Ghose filter | Yes |
| Veber filter | Yes |
| Muegge Filter | Yes |
| Similarity Search | Human metabolite database | FDA approved drugs |