NPACT

STATISTICS

1. General Information

Total No. of Compounds	Total No. of Refrences	Total No. of Cell Lines	Total No. of Cancers	Total No. Classes	Compound-Cell Line Interactions	Compound-target interaction
1574	762	353	19	27	5214	1980

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2. Comparision with other databases

The comparison with 3 other similar natural compound collections (HIT, Super Natural and Cancer Resource) with NPACT reveals that 880 compounds (56%) are unique. Individually we find that 1417,1390 and 1185 compounds are not found in HIT, Super Natural and Cancer Resource

    

DATABASES	REDUNDANT	UNIQUE
Super Natural Database	184	1390
HIT	157	1417
Cancer Resource	389	1185
CTD	663	911
PubChem	1297	277

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3. Cancer-wise distribution of the compounds

       

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4. Cancer-wise distribution of Cell-lines

       

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5. Distribution of classes of compound

S No.	Classes	No. of Compounds
1	Terpenoids	513
2	Flavonoids	329
3	Alkaloids	110
4	Not Classified	35
5	Polyketides	92
6	Lignans	88
7	Polycyclic aromatic natural products	63
8	Steroids	80
9	Simple aromatic natural products	82
10	Saponin	51
11	Carbohydrates	11
12	Organic Chemicals	33
13	Oxygen heterocycles	12
14	Benzopyranoids	26
15	Benzofuranoids	19
16	Aliphatic natural products	20
17	Aminoacids and peptides	3
18	Polypyrroles	1
19	Tannin	6

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6. Distribution of Molecular Mass

       

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7. Distribution of Polar Surface Area

       

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8. Distribution of Hydrogen Donor

       

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9. Distribution of Hydrogen Acceptor

       

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10. Distribution of LogP

       

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11. Year-wise distribution of literature in NPACT

       

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12. Top 10 journals refered in NPACT

A total of 181 journals have been refered corresponding to 762 papers while creating NPACT. The distribution for top 10 journals which have conributed maximally in developing NPACT is shown.

       

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13. Top 15 targets present in NPACT

       

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14. Distribution of Suppliers

       

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15. Distribution of compounds per Cell line

S.No.	Cell Lines	Compounds	S.No.	Cell Lines	Compounds	S.No.	Cell Lines	Compounds	S.No.	Cell Lines	Compounds
1	1483	1	90	H295R	3	179	KB-V(+VLB)	6	268	R-HepG2	1
2	8898	1	91	H-358	1	180	KB-V(-VLB)	1	269	RKO	1
3	(RBL)-2H3	1	92	H-441	1	181	KB-V1	16	270	RPMI	6
4	103E	4	93	H-460	22	182	KB-V1-	2	271	RPMI-7951	5
5	1A9	8	94	H4-II-E	8	183	KB-V1+	2	272	RPMI-8226	7
6	1F6	2	95	H520	2	184	KBv200	2	273	RPMT-8226	1
7	22Rv1	4	96	H-661	1	185	KB-VIN	24	274	RT4	3
8	26-L5	38	97	H-7402	3	186	KM-12	4	275	RXF 486L	5
9	3LL	12	98	H-929	1	187	KM20L2	3	276	RXF 944L	5
10	786-0	4	99	HA59T	3	188	L1210	6	277	RXF-393	6
11	95D	3	100	HaCaT	1	189	L5178y	13	278	SB1	2
12	9KB	2	101	HCC-2998	5	190	L6	13	279	SB3	2
13	A-2780	29	102	HCC-44B2	3	191	L929	20	280	SCABER	3
14	A-298	2	103	HCC-50D3	1	192	LAC	3	281	SCC15	1
15	A-375	10	104	HCE7	1	193	LM-3	3	282	SCC25	1
16	A375-S2	1	105	HCT-116	55	194	LNCaP	93	283	Seg-1	1
17	A-427	1	106	HCT-15	60	195	LoVo	7	284	SF-268	52
18	A-431	19	107	HCT-8	26	196	LOX-IMVI	24	285	SF-295	7
19	A-498	53	108	HEC-46R1	2	197	LP07	1	286	SF-539	9
20	A-5408	11	109	HEK-293	6	198	LS174T	1	287	SGC-7901	21
21	A549	343	110	HeLa	97	199	LTEP-a-2	2	288	SH101-P4	3
22	A549-T12	2	111	Hela-S3	1	200	LU-1	62	289	SH-J1	1
23	ACHN	21	112	Hela-TG	1	201	LXFA 629L	5	290	SH-SY5Y	1
24	AGS	12	113	Hep 2,2,15	1	202	LXFL 529L	5	291	SiHa	1
25	AsPC-1	1	114	Hep G2	118	203	M-109	9	292	SK-28	2
26	B16	36	115	HEp-2	31	204	M-14	3	293	SK-37	2
27	B16 melanoma 4A5	25	116	Hep-3B	16	205	M21	1	294	SK-BR-3	2
28	B16(F10)	24	117	Hepa 1c1c7	66	206	M-4-BEU	3	295	SKCO1	1
29	B16-BL6	22	118	Hepa59T/VGH	6	207	Malme-3M	14	296	SK-LU1	6
30	B16-F0	3	119	HEPA-2B	1	208	MAXF 401NL	5	297	SK-Mel-103	1
31	B16-F1	4	120	HEPA-3B	5	209	MB-MDA-231	1	298	SK-Mel-147	1
32	BC	15	121	Het-1a	1	210	MCF-10A	2	299	SK-MEL-2	40
33	BC-1	46	122	HL-60	217	211	MCF-7	466	300	SK-Mel-28	7
34	Bcap-37	3	123	HL-60/MX2	2	212	MCF-7/TH	1	301	SK-MEL-30	4
35	BEL-7402	16	124	HN12	1	213	MDA231	1	302	SK-MEL-5	20
36	BFTC-905	3	125	HN17	1	214	MDA-MB-231	37	303	SK-MES-1	1
37	BGC	1	126	HO-4980	1	215	MDA-MB-273	1	304	SK-N-AS	2
38	BGC-823	11	127	HO-8910	7	216	MDA-MB-435	11	305	SKNSH	7
39	Bic-1	1	128	HONE-1	12	217	MDA-MB-435 ER-	9	306	SK-OV-3	31
40	BPrc1	3	129	HOP-62	1	218	MDA-MB-453	3	307	SMMC-7541	11
41	BT-20	3	130	HOP-92	5	219	MDA-MB-468	14	308	SMMC-7721	7
42	BT-474	1	131	HOS	7	220	MDA-N	1	309	SN-12C	2
43	BT-549	4	132	HOS-1	5	221	MDCK	1	310	SNB-19	2
44	BxPC-3	4	133	HPCC	1	222	ME-180	2	311	SNB-75	5
45	C32	6	134	HPGBM	1	223	ME-308	6	312	SNB-78	1
46	C4-2	1	135	HPOC	1	224	Mel2	12	313	SNU-C5	14
47	C6	7	136	HS27A	1	225	MEL-28	1	314	SPC-A-1	4
48	Caco-2	37	137	HS578T	3	226	MEXF 462NL	5	315	SR	1
49	CAKI	3	138	HSC-2	39	227	MEXF 514L	5	316	SW-1116	1
50	CAKI-1	3	139	HSC-3	10	228	MGC-803	3	317	SW-480	21
51	CaOV3	7	140	HSC-39K6	1	229	MiaPaCa-2	6	318	SW-620	16
52	Capan-1	2	141	HSC-40A1	1	230	MKN-28	9	319	SW-626	7
53	Caski	2	142	HSC-41E6	2	231	MKN-45	9	320	SW-680	2
54	CCRF-CEM	9	143	HSC-42H	1	232	MKN-7	1	321	SW-872	2
55	CCRF-HSB-2	25	144	HSC-43C1	1	233	Molt-4	20	322	SW-900	1
56	CEM	7	145	HSC-45M2	3	234	Molt-4F	3	323	T24	6
57	CEM/ADR5000	2	146	HSG	26	235	MRC5	5	324	T-47D	14
58	CEM-SS	7	147	HT	12	236	MV3	2	325	T-47D-ER-	1
59	ChaGo-K-1	1	148	HT-1080	65	237	NALM-6	1	326	TAOc1BPrc1	3
60	CL1-0	9	149	HT-1197	8	238	NCI/ADR-RES	3	327	TE-671	5
61	CL1-5	1	150	HT-1376	3	239	NCI-60	12	328	TGBC11TKB	25
62	CNE	2	151	HT-144	2	240	NCI-H187	38	329	THP-1	1
63	CNE3	2	152	HT-29	193	241	NCI-H226	1	330	TK-10	8
64	Col-2	39	153	HTB 140	1	242	NCI-H23	4	331	TrHBMEC	1
65	Colo-205	19	154	HUH7	10	243	NCI-H322M	1	332	TSGH	1
66	Colo-320	3	155	HUVEC	3	244	NCI-H460	25	333	TSGH8301	3
67	COLO320DM	1	156	IA9	3	245	NCI-H522	6	334	U-251	17
68	Colo-38	2	157	IA9-PTX10	3	246	NCI-H69	1	335	U-266	1
69	Colon 26	1	158	IEC6	1	247	NGP	1	336	U-373	15
70	Colon 26-L5	51	159	IGROV1	6	248	OVCAR-3	11	337	U-87-MG	10
71	COR-L23	6	160	J774	8	249	OVCAR-4	1	338	U-937	28
72	CRL-1579	3	161	J-774-A1	1	250	OVCAR-5	5	339	UACC-257	1
73	CT-26	3	162	J82	5	251	OVCAR-8	6	340	UACC-62	11
74	DBTRG	2	163	JB6	9	252	P-388	140	341	UM-22b	1
75	DLA	1	164	Jurkat	12	253	PA-1	1	342	UM-SCC-1	1
76	DLD-1	14	165	Jurkat E6.1	17	254	PACA-2	51	343	UM-SCC-17B	1
77	DMS-114	10	166	JurkatCAM1.6	2	255	PANC-1	4	344	UO-31	17
78	DU-145	44	167	K-562	68	256	PC-3	138	345	UXF 1138L	5
79	EAhy-926	2	168	K562/ADM	2	257	PC-3M	1	346	W-256	1
80	Eca-109	4	169	K562-r	1	258	PC-6	5	347	WEHI-164	13
81	EKVX	1	170	K562-s	1	259	PCI-37a	1	348	WI-38	17
82	FM3A	9	171	KATO-III	1	260	PF-382	2	349	WIDR	1
83	FTC238	1	172	KB	298	261	PK-1	1	350	WS1	2
84	G361	5	173	KB-16	7	262	PLC/PRF/5	2	351	X-17	2
85	GBC-SD	1	174	KB-3-1	6	263	PMN	3	352	XF-498	2
86	GTB	2	175	KB-7d	4	264	PTX10	8	353	ZR-75-1	23
87	GXF 251L	5	176	KB-C2	8	265	Raji	1	-	-	-
88	H1299	2	177	KB-CPT	3	266	RAW264	15	-	-	-
89	H1975	1	178	KB-TAX50	2	267	RAW264.7	8	-	-	-