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Peptide Hormone

Search Result - 1

HMRbase accession number	10334
Swiss-prot Accession number	Q8CIT0 (Sequence in FASTA format)
Description	Corticoliberin precursor (Corticotropin-releasing factor) (CRF)(Corticotropin-releasing hormone).
Source organism	Mus musculus (Mouse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This hormone from hypothalamus regulates the release of corticotropin from pituitary gland
Protein Length	187 Amino acids
Molecular weight	20778
References	1   Seasholtz A.F., Bourbonais F.J., Harnden C.E., Camper S.A.; "Nucleotide sequence and expression of the mouse corticotropin-releasing hormone gene."; Mol. Cell. Neurosci. 2:266-273(1991).
Domain Name	CRF
Hormone Name	Corticoliberin
Mature Hormone Sequence	SEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII
Position of mature hormone in Pre-Hormone protein	41 Residues from position (145-185)
Receptor	P35347   Detail in HMRbase    Q60748    Detail in HMRbase
Gene ID	12918
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 2

HMRbase accession number	10344
Swiss-prot Accession number	Q95MI6 (Sequence in FASTA format)
Description	Corticoliberin precursor (Corticotropin-releasing factor) (CRF)(Corticotropin-releasing hormone).
Source organism	Bos taurus (Bovine)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This hormone from hypothalamus regulates the release of corticotropin from pituitary gland
Protein Length	190 Amino acids
Molecular weight	20739
References	1   Buchanan F.C., Thue T.D., Schmutz S.M.; "Sequence analysis of bovine corticotrophin-releasing hormone - acandidate gene for post-natal growth."; Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
Domain Name	CRF
Hormone Name	Corticoliberin
Mature Hormone Sequence	SQEPPISLDLTFHLLREVLEMTKADQLAQQAHXNRKLLDIA
Position of mature hormone in Pre-Hormone protein	41 Residues from position (148-188)
Receptor	Q9BGU4    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 3

HMRbase accession number	10359
Swiss-prot Accession number	Q9PTS1 (Sequence in FASTA format)
Description	Corticoliberin precursor (Corticotropin-releasing factor) (CRF)(Corticotropin-releasing hormone).
Source organism	Carassius auratus (Goldfish)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This hormone from hypothalamus regulates the release of corticotropin from pituitary gland
Protein Length	162 Amino acids
Molecular weight	18418
References	1  PubMed abstract 10603283
Domain Name	CRF
Hormone Name	Corticoliberin
Mature Hormone Sequence	SEEPPISLDLTFHLLREVLEMARAEQMAQQAHSNRKMMEIF
Position of mature hormone in Pre-Hormone protein	41 Residues from position (120-160)
Receptor	Q49MT7   Detail in HMRbase    Q49MT8    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 4

HMRbase accession number	10590
Swiss-prot Accession number	P49926 (Sequence in FASTA format)
Description	Corticoliberin precursor (Corticotropin-releasing factor) (CRF)(Corticotropin-releasing hormone).
Source organism	Canis familiaris (Dog)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This hormone from hypothalamus regulates the release of corticotropin from pituitary gland
Protein Length	196 Amino acids
Molecular weight	21547
References	1   Kansaku N., Yamagishi K., Mizushima S.; "PCR cloning of dog corticotropin releasing hormone gene."; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. 2  PubMed abstract 7969821
Domain Name	CRF
Hormone Name	Corticoliberin
Mature Hormone Sequence	SEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII
Position of mature hormone in Pre-Hormone protein	41 Residues from position (154-194)
Receptor	N/A
Gene ID	486977
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 5

HMRbase accession number	10591
Swiss-prot Accession number	P06296 (Sequence in FASTA format)
Description	Corticoliberin precursor (Corticotropin-releasing factor) (CRF)(Corticotropin-releasing hormone).
Source organism	Sus scrofa (Pig)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This hormone from hypothalamus regulates the release of corticotropin from pituitary gland
Protein Length	191 Amino acids
Molecular weight	21042
References	1  PubMed abstract 9734873 2  PubMed abstract 12030933 3  PubMed abstract 3878520
Domain Name	CRF
Hormone Name	Corticoliberin
Mature Hormone Sequence	SEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII
Position of mature hormone in Pre-Hormone protein	41 Residues from position (149-189)
Receptor	N/A
Gene ID	100127468
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 6

HMRbase accession number	11241
Swiss-prot Accession number	P01142 (Sequence in FASTA format)
Description	Corticoliberin precursor (Corticotropin-releasing factor) (CRF)(Corticotropin-releasing hormone) (Endorpholiberin).
Source organism	Ovis aries (Sheep)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This hormone from hypothalamus regulates the release of corticotropin from pituitary gland
Protein Length	190 Amino acids
Molecular weight	20672
References	1  PubMed abstract 6600512 2  PubMed abstract 3265687 3  PubMed abstract 6273874 4  PubMed abstract 6267699 5  PubMed abstract 2647152
Domain Name	CRF
Hormone Name	Corticoliberin
Mature Hormone Sequence	SQEPPISLDLTFHLLREVLEMTKADQLAQQAHSNRKLLDIA
Position of mature hormone in Pre-Hormone protein	41 Residues from position (148-188)
Receptor	O62772    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 7

HMRbase accession number	11242
Swiss-prot Accession number	P01143 (Sequence in FASTA format)
Description	Corticoliberin precursor (Corticotropin-releasing factor) (CRF)(Corticotropin-releasing hormone).
Source organism	Rattus norvegicus (Rat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This hormone from hypothalamus regulates the release of corticotropin from pituitary gland
Protein Length	187 Amino acids
Molecular weight	20680
References	1  PubMed abstract 3876950 2  PubMed abstract 3274895 3  PubMed abstract 6603620
Domain Name	CRF
Hormone Name	Corticoliberin
Mature Hormone Sequence	SEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII
Position of mature hormone in Pre-Hormone protein	41 Residues from position (145-185)
Receptor	P35353   Detail in HMRbase    P47866    Detail in HMRbase
Gene ID	81648
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 8

HMRbase accession number	11377
Swiss-prot Accession number	P06850 (Sequence in FASTA format)
Description	Corticoliberin precursor (Corticotropin-releasing factor) (CRF)(Corticotropin-releasing hormone).
Source organism	Homo sapiens (Human)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This hormone from hypothalamus regulates the release of corticotropin from pituitary gland
Protein Length	196 Amino acids
Molecular weight	21422
References	1  PubMed abstract 6605851 2  PubMed abstract 2783917 3   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 4  PubMed abstract 15489334 5  PubMed abstract 3262120 6  PubMed abstract 8386360
Domain Name	CRF
Hormone Name	Corticoliberin
Mature Hormone Sequence	SEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEII
Position of mature hormone in Pre-Hormone protein	41 Residues from position (154-194)
Receptor	P34998   Detail in HMRbase    Q13324    Detail in HMRbase
Gene ID	1392
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 9

HMRbase accession number	11467
Swiss-prot Accession number	P49188 (Sequence in FASTA format)
Description	Corticoliberin precursor (Corticotropin-releasing factor) (CRF)(Corticotropin-releasing hormone).
Source organism	Xenopus laevis (African clawed frog)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	This hormone from hypothalamus regulates the release of corticotropin from pituitary gland
Protein Length	162 Amino acids
Molecular weight	17880
References	1  PubMed abstract 1448118 2   Yao M., Stenzel-Poore M.P., Denver R.J.; "Structural and functional analysis of corticotropin-releasing factorgenes of the South African clawed frog, Xenopus laevis."; Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
Domain Name	CRF
Hormone Name	Corticoliberin
Mature Hormone Sequence	AEEPPISLDLTFHLLREVLEMARAEQIAQQAHSNRKLMDII
Position of mature hormone in Pre-Hormone protein	41 Residues from position (120-160)
Receptor	O42602   Detail in HMRbase    O42603    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments