A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11243 |
| Swiss-prot Accession number | P01148 (Sequence in FASTA format) |
| Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I) (Gonadorelin); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Secreted protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the GnRH family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
| Protein Length | 92 Amino acids |
| Molecular weight | 10380 |
| References | 1 PubMed abstract 2671939 2 PubMed abstract 2867548 3 PubMed abstract 6090951 4 PubMed abstract 15489334 5 PubMed abstract 6760865 6 PubMed abstract 10391209 7 Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). |
| Domain Name | N/A |
| Hormone Name | Gonadoliberin-1 |
| Mature Hormone Sequence | QHWSYGLRPG |
| Position of mature hormone in Pre-Hormone protein | 10 Residues from position (24-33) |
| Receptor | P30968
Detail in HMRbase |
| Gene ID | 2796 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |