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Non-peptide Hormone

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HMRbase accession number1358
PubChem ID5280879
Hormone nameLeukotriene E4
DescriptionA biologically active principle of SRS-A that is formed from LEUKOTRIENE D4 via a peptidase reaction that removes the glycine residue. The biological actions of LTE4 are similar to LTC4 and LTD4. (From Dictionary of Prostaglandins and Related Compounds, 1990)
Synonymsleukotriene E4 Leukotriene E4 LTE4 5S-hydroxy,6R-(S-cysteinyl),7E,9E,11Z,14Z-eicosatetraenoic acid (7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-hydroxyeicosa-7,9,11,1 4-tetraenoate
Molecular weight439.61
Molecular formulaC23H37NO5S
IUPAC Name(5S,6R,7E,9E,11Z,14Z)-6-[(2R)-2-amino-3-hydroxy-3-oxopropyl]sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoic acid
Canonical smilesCCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)O)N
Isomeric smilesCCCCCC=C/CC=C/C=C/C=C/[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)O)N
Structure
   
PDB file
SDF file
MOL file
PDB IDN/A
KEGG IDC05952  
HMDB IDN/A
Melting PointN/A
Log PN/A
Water SolubilityN/A
DrugBank IDN/A
Drugpediawiki
ReceptorQ9NS75   Detail in HMRbase   
Q9Y271   Detail in HMRbase   
Comments
ReferencesEndonet