A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 1003 |
| PubChem ID | 92810 |
| Hormone name | 5-alpha-Dihydroprogesterone |
| Description | A biologically active 5-alpha-reduced metabolite of plasma PROGESTERONE. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (ALLOPREGNANOLONE), a neuroactive steroid that binds with GABA(A) RECEPTOR. |
| Synonyms | 3,20-Allopregnanedione 5-alpha-Dihydroprogesterone 3,20-Dioxo-5alpha-pregnane 5alpha-Pregnane-3,20-dione Allopregnane-3,20-dione 5beta-Pregnane-3,20-dione |
| Molecular weight | 316.48 |
| Molecular formula | C21H32O2 |
| IUPAC Name | (5S,8R,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one |
| Canonical smiles | CC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(=O)C4)C)C |
| Isomeric smiles | CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CCC(=O)C4)C)C
|
| Structure | |
| PDB file | |
| SDF file | |
| MOL file | |
| PDB ID | N/A |
| KEGG ID | C03681 |
| HMDB ID | HMDB03759 |
| Melting Point | 200(EXP) |
| Log P | 3.46(EST) |
| Water Solubility | N/A |
| DrugBank ID | N/A |
| Drugpedia | wiki |
| Receptor | Q9GLW0 Detail in HMRbase P07812 Detail in HMRbase P06401 Detail in HMRbase P79373 Detail in HMRbase Q00175 Detail in HMRbase P06186 Detail in HMRbase Q8AYI2 Detail in HMRbase Q63449 Detail in HMRbase Q28590 Detail in HMRbase Q6Q6S5 Detail in HMRbase Q8NG42 Detail in HMRbase Q8NG43 Detail in HMRbase Q8NG44 Detail in HMRbase Q8TDS3 Detail in HMRbase Q8UVY3 Detail in HMRbase |
| Comments | !Link to Receptor is not Organism Specific |
| References | Pubchem,HMDB |