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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
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Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TP53 | AIYKQYKQS | LUNG | 161 | p.165_166insYKQ | c.496_497insACAAGCAGT | In_Frame_Ins | 4 | 0.11 | NCIH727 | N | 1 | 0 | 0 | N | ||||||||||||
TP53 | AMAIYKQYK | LUNG | 159 | p.165_166insYKQ | c.496_497insACAAGCAGT | In_Frame_Ins | 2 | 0.11 | NCIH727 | N | 6 | 0 | 0 | N | ||||||||||||
TP53 | IYKQYKQSQ | LUNG | 162 | p.165_166insYKQ | c.496_497insACAAGCAGT | In_Frame_Ins | 4 | 0.11 | NCIH727 | N | 0 | 0 | 11 | N | ||||||||||||
TP53 | KQYKQSQHM | LUNG | 164 | p.165_166insYKQ | c.496_497insACAAGCAGT | In_Frame_Ins | 2 | 0.11 | NCIH727 | N | 10 | 0 | 0 | N | ||||||||||||
TP53 | MAIYKQYKQ | LUNG | 160 | p.165_166insYKQ | c.496_497insACAAGCAGT | In_Frame_Ins | 3 | 0.11 | NCIH727 | N | 0 | 0 | 10 | N | ||||||||||||
TP53 | QYKQSQHMT | LUNG | 165 | p.165_166insYKQ | c.496_497insACAAGCAGT | In_Frame_Ins | 1 | 0.11 | NCIH727 | N | 2 | 0 | 0 | N | ||||||||||||
TP53 | RAMAIYKQY | LUNG | 158 | p.165_166insYKQ | c.496_497insACAAGCAGT | In_Frame_Ins | 1 | 0.11 | NCIH727 | N | 7 | 0 | 0 | N | ||||||||||||
TP53 | YKQYKQSQH | LUNG | 163 | p.165_166insYKQ | c.496_497insACAAGCAGT | In_Frame_Ins | 3 | 0.11 | NCIH727 | N | 3 | 0 | 4 | N | ||||||||||||