Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MLL3 | CGKCYPELQ | KIDNEY | 470 | p.H475del | c.1424_1426delATC | In_Frame_Del | 4 | 0.11 | A704 | N | 0 | 0 | 0 | Y | ||||||||||||
| MLL3 | CPFCGKCYP | KIDNEY | 467 | p.H475del | c.1424_1426delATC | In_Frame_Del | 1 | 0.11 | A704 | N | 2 | 0 | 0 | N | ||||||||||||
| MLL3 | CRYLCSIEK | LARGE_INTESTINE | 4596 | p.E4604del | c.13810_13812delGAG | In_Frame_Del | 1 | 0.11 | CW2 | Y | 2 | 9 | 0 | N | ||||||||||||
| MLL3 | CSIEKDGRP | LARGE_INTESTINE | 4600 | p.E4604del | c.13810_13812delGAG | In_Frame_Del | 3 | 0.11 | CW2 | N | 0 | 0 | 0 | N | ||||||||||||
| MLL3 | CYPELQKDM | KIDNEY | 473 | p.H475del | c.1424_1426delATC | In_Frame_Del | 2 | 0.11 | A704 | N | 6 | 0 | 0 | Y | ||||||||||||
| MLL3 | DISGREIFK | CENTRAL_NERVOUS_SYSTEM | 861 | p.E864del | c.2591_2593delAAG | In_Frame_Del | 3 | 0.11 | LN18 | Y | 4 | 11 | 0 | N | ||||||||||||
| MLL3 | FCGKCYPEL | KIDNEY | 469 | p.H475del | c.1424_1426delATC | In_Frame_Del | 3 | 0.11 | A704 | N | 11 | 0 | 0 | N | ||||||||||||
| MLL3 | GKCYPELQK | KIDNEY | 471 | p.H475del | c.1424_1426delATC | In_Frame_Del | 4 | 0.11 | A704 | N | 1 | 0 | 0 | Y | ||||||||||||
| MLL3 | IEKDGRPVF | LARGE_INTESTINE | 4602 | p.E4604del | c.13810_13812delGAG | In_Frame_Del | 1 | 0.11 | CW2 | Y | 8 | 9 | 4 | N | ||||||||||||
| MLL3 | ISGREIFKP | CENTRAL_NERVOUS_SYSTEM | 862 | p.E864del | c.2591_2593delAAG | In_Frame_Del | 2 | 0.11 | LN18 | N | 0 | 0 | 0 | N | ||||||||||||
| MLL3 | KCYPELQKD | KIDNEY | 472 | p.H475del | c.1424_1426delATC | In_Frame_Del | 3 | 0.11 | A704 | N | 0 | 0 | 0 | N | ||||||||||||
| MLL3 | LCSIEKDGR | LARGE_INTESTINE | 4599 | p.E4604del | c.13810_13812delGAG | In_Frame_Del | 4 | 0.11 | CW2 | N | 3 | 0 | 0 | N | ||||||||||||
| MLL3 | PDISGREIF | CENTRAL_NERVOUS_SYSTEM | 860 | p.E864del | c.2591_2593delAAG | In_Frame_Del | 4 | 0.11 | LN18 | N | 1 | 0 | 0 | N | ||||||||||||
| MLL3 | PFCGKCYPE | KIDNEY | 468 | p.H475del | c.1424_1426delATC | In_Frame_Del | 2 | 0.11 | A704 | N | 0 | 0 | 0 | Y | ||||||||||||
| MLL3 | PSWSPDISG | CENTRAL_NERVOUS_SYSTEM | 856 | p.E864del | c.2591_2593delAAG | In_Frame_Del | 1 | 0.11 | LN18 | N | 0 | 0 | 0 | N | ||||||||||||
| MLL3 | RYLCSIEKD | LARGE_INTESTINE | 4597 | p.E4604del | c.13810_13812delGAG | In_Frame_Del | 2 | 0.11 | CW2 | N | 0 | 0 | 0 | N | ||||||||||||
| MLL3 | SGREIFKPR | CENTRAL_NERVOUS_SYSTEM | 863 | p.E864del | c.2591_2593delAAG | In_Frame_Del | 1 | 0.11 | LN18 | N | 1 | 0 | 0 | N | ||||||||||||
| MLL3 | SIEKDGRPV | LARGE_INTESTINE | 4601 | p.E4604del | c.13810_13812delGAG | In_Frame_Del | 2 | 0.11 | CW2 | N | 0 | 0 | 0 | N | ||||||||||||
| MLL3 | SPDISGREI | CENTRAL_NERVOUS_SYSTEM | 859 | p.E864del | c.2591_2593delAAG | In_Frame_Del | 4 | 0.11 | LN18 | N | 13 | 0 | 0 | N | ||||||||||||
| MLL3 | SWSPDISGR | CENTRAL_NERVOUS_SYSTEM | 857 | p.E864del | c.2591_2593delAAG | In_Frame_Del | 2 | 0.11 | LN18 | N | 2 | 0 | 0 | N | ||||||||||||
| MLL3 | WSPDISGRE | CENTRAL_NERVOUS_SYSTEM | 858 | p.E864del | c.2591_2593delAAG | In_Frame_Del | 3 | 0.11 | LN18 | N | 2 | 0 | 0 | N | ||||||||||||
| MLL3 | YLCSIEKDG | LARGE_INTESTINE | 4598 | p.E4604del | c.13810_13812delGAG | In_Frame_Del | 3 | 0.11 | CW2 | N | 3 | 0 | 0 | N | ||||||||||||
| MLL3 | YPELQKDML | KIDNEY | 474 | p.H475del | c.1424_1426delATC | In_Frame_Del | 1 | 0.11 | A704 | N | 15 | 0 | 0 | Y | ||||||||||||
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