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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
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Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ERBB2 | AVCVGSPYV | LUNG | 775 | p.776_776G>VC | c.2326_2327insTGT | In_Frame_Ins | 3 | 0.11 | NCIH1781 | Y | 2 | 11 | 0 | N | ||||||||||||
ERBB2 | AYVMAVCVG | LUNG | 771 | p.776_776G>VC | c.2326_2327insTGT | In_Frame_Ins | 4 | 0.11 | NCIH1781 | N | 0 | 0 | 0 | N | ||||||||||||
ERBB2 | CVGSPYVSR | LUNG | 777 | p.776_776G>VC | c.2326_2327insTGT | In_Frame_Ins | 1 | 0.11 | NCIH1781 | Y | 6 | 10 | 0 | N | ||||||||||||
ERBB2 | DEAYVMAVC | LUNG | 769 | p.776_776G>VC | c.2326_2327insTGT | In_Frame_Ins | 2 | 0.11 | NCIH1781 | N | 6 | 0 | 0 | N | ||||||||||||
ERBB2 | EAYVMAVCV | LUNG | 770 | p.776_776G>VC | c.2326_2327insTGT | In_Frame_Ins | 3 | 0.11 | NCIH1781 | N | 6 | 0 | 0 | N | ||||||||||||
ERBB2 | MAVCVGSPY | LUNG | 774 | p.776_776G>VC | c.2326_2327insTGT | In_Frame_Ins | 4 | 0.11 | NCIH1781 | N | 8 | 0 | 0 | N | ||||||||||||
ERBB2 | VCVGSPYVS | LUNG | 776 | p.776_776G>VC | c.2326_2327insTGT | In_Frame_Ins | 2 | 0.11 | NCIH1781 | N | 0 | 0 | 1 | N | ||||||||||||
ERBB2 | VMAVCVGSP | LUNG | 773 | p.776_776G>VC | c.2326_2327insTGT | In_Frame_Ins | 5 | 0.11 | NCIH1781 | N | 0 | 0 | 0 | N | ||||||||||||
ERBB2 | YVMAVCVGS | LUNG | 772 | p.776_776G>VC | c.2326_2327insTGT | In_Frame_Ins | 5 | 0.11 | NCIH1781 | N | 2 | 0 | 48 | N | ||||||||||||
ERBB2 | LDEAYVMAV | LUNG | 768 | p.776_776G>VC | c.2326_2327insTGT | In_Frame_Ins | 1 | 0.22 | NCIH1781 | N | 7 | 0 | 0 | N | ||||||||||||