Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
CTNNB1APLSGKGNPSKIN43p.S45delc.131_133delCTTIn_Frame_Del20.22COLO783N000N
CTNNB1APLSGKGNPLARGE_INTESTINE43p.S45delc.131_133delCTTIn_Frame_Del20.22HCT116N000N
CTNNB1ATTTAPLSGSKIN39p.S45delc.131_133delCTTIn_Frame_Del30.22COLO783N000N
CTNNB1ATTTAPLSGLARGE_INTESTINE39p.S45delc.131_133delCTTIn_Frame_Del30.22HCT116N000N
CTNNB1GATTTAPLSSKIN38p.S45delc.131_133delCTTIn_Frame_Del20.22COLO783N100N
CTNNB1GATTTAPLSLARGE_INTESTINE38p.S45delc.131_133delCTTIn_Frame_Del20.22HCT116N100N
CTNNB1SGATTTAPLSKIN37p.S45delc.131_133delCTTIn_Frame_Del10.22COLO783N1000N
CTNNB1SGATTTAPLLARGE_INTESTINE37p.S45delc.131_133delCTTIn_Frame_Del10.22HCT116N1000N
CTNNB1TAPLSGKGNSKIN42p.S45delc.131_133delCTTIn_Frame_Del30.22COLO783N100N
CTNNB1TAPLSGKGNLARGE_INTESTINE42p.S45delc.131_133delCTTIn_Frame_Del30.22HCT116N100N
CTNNB1TTAPLSGKGSKIN41p.S45delc.131_133delCTTIn_Frame_Del30.22COLO783N000N
CTNNB1TTAPLSGKGLARGE_INTESTINE41p.S45delc.131_133delCTTIn_Frame_Del30.22HCT116N000N
CTNNB1TTTAPLSGKSKIN40p.S45delc.131_133delCTTIn_Frame_Del30.22COLO783N200N
CTNNB1TTTAPLSGKLARGE_INTESTINE40p.S45delc.131_133delCTTIn_Frame_Del30.22HCT116N200N
CTNNB1PLSGKGNPESKIN44p.S45delc.131_133delCTTIn_Frame_Del10.33COLO783N000N
CTNNB1PLSGKGNPELARGE_INTESTINE44p.S45delc.131_133delCTTIn_Frame_Del10.33HCT116N000N