Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
CDH1AEKRVEVSESTOMACH483p.PIFVPP484delc.1448_1465delCCCCCATCTTTGTGCCTCIn_Frame_Del10.11NCCSTCK140N000N
CDH1CPFPKNLVQLUNG163p.PENEKG164delc.488_505delGCCCAGAAAATGAAAAAGIn_Frame_Del10.11NCIH2122N100N
CDH1DVLDVNEAESTOMACH476p.PIFVPP484delc.1448_1465delCCCCCATCTTTGTGCCTCIn_Frame_Del10.11NCCSTCK140N000N
CDH1DVNEAEKRVSTOMACH479p.PIFVPP484delc.1448_1465delCCCCCATCTTTGTGCCTCIn_Frame_Del30.11NCCSTCK140N400N
CDH1EAEKRVEVSSTOMACH482p.PIFVPP484delc.1448_1465delCCCCCATCTTTGTGCCTCIn_Frame_Del20.11NCCSTCK140N200N
CDH1IPPISCPFPLUNG158p.PENEKG164delc.488_505delGCCCAGAAAATGAAAAAGIn_Frame_Del20.11NCIH2122N100N
CDH1ISCPFPKNLLUNG161p.PENEKG164delc.488_505delGCCCAGAAAATGAAAAAGIn_Frame_Del30.11NCIH2122Y11100N
CDH1LDVNEAEKRSTOMACH478p.PIFVPP484delc.1448_1465delCCCCCATCTTTGTGCCTCIn_Frame_Del30.11NCCSTCK140N000N
CDH1NEAEKRVEVSTOMACH481p.PIFVPP484delc.1448_1465delCCCCCATCTTTGTGCCTCIn_Frame_Del30.11NCCSTCK140Y8120N
CDH1PISCPFPKNLUNG160p.PENEKG164delc.488_505delGCCCAGAAAATGAAAAAGIn_Frame_Del40.11NCIH2122N000N
CDH1PPISCPFPKLUNG159p.PENEKG164delc.488_505delGCCCAGAAAATGAAAAAGIn_Frame_Del30.11NCIH2122N000N
CDH1SCPFPKNLVLUNG162p.PENEKG164delc.488_505delGCCCAGAAAATGAAAAAGIn_Frame_Del20.11NCIH2122N000N
CDH1VIPPISCPFLUNG157p.PENEKG164delc.488_505delGCCCAGAAAATGAAAAAGIn_Frame_Del10.11NCIH2122N700N
CDH1VLDVNEAEKSTOMACH477p.PIFVPP484delc.1448_1465delCCCCCATCTTTGTGCCTCIn_Frame_Del20.11NCCSTCK140Y5140N
CDH1VNEAEKRVESTOMACH480p.PIFVPP484delc.1448_1465delCCCCCATCTTTGTGCCTCIn_Frame_Del40.11NCCSTCK140N001N