Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
CARD10AQLSEKNSAENDOMETRIUM214p.E219delc.655_657delGAGIn_Frame_Del40.11HEC108N200N
CARD10LAQLSEKNSENDOMETRIUM213p.E219delc.655_657delGAGIn_Frame_Del30.11HEC108N100N
CARD10LSEKNSAVLENDOMETRIUM216p.E219delc.655_657delGAGIn_Frame_Del20.11HEC108N800N
CARD10MRLAQLSEKENDOMETRIUM211p.E219delc.655_657delGAGIn_Frame_Del10.11HEC108Y21018N
CARD10QLSEKNSAVENDOMETRIUM215p.E219delc.655_657delGAGIn_Frame_Del30.11HEC108Y6100N
CARD10RLAQLSEKNENDOMETRIUM212p.E219delc.655_657delGAGIn_Frame_Del20.11HEC108N000N
CARD10SEKNSAVLRENDOMETRIUM217p.E219delc.655_657delGAGIn_Frame_Del10.11HEC108N000N