Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
RB1ARLFLIMIKLUNG333p.L337fsc.1011_1011delGFrame_Shift_Del30.11COLO668Y2100N
RB1DARLFLIMILUNG332p.L337fsc.1011_1011delGFrame_Shift_Del30.11COLO668Y9100N
RB1ENLIPILTTLUNG398p.I401fsc.1202_1202delTFrame_Shift_Del50.11HCC33N000Y
RB1FLDHDNSSDCENTRAL_NERVOUS_SYSTEM336p.K341fsc.1021_1022delAAFrame_Shift_Del40.1142MGBAN200N
RB1FLIMIKLFRLUNG336p.L337fsc.1011_1011delGFrame_Shift_Del50.11COLO668N9038N
RB1IMIKLFRLILUNG338p.L337fsc.1011_1011delGFrame_Shift_Del50.11COLO668N15016N
RB1KNVYFKILYENDOMETRIUM289p.K294fsc.880_880delAFrame_Shift_Del30.11ISHIKAWAHERAKLIO02ERN700N
RB1LDARLFLIMLUNG331p.L337fsc.1011_1011delGFrame_Shift_Del20.11COLO668N800N
RB1LFLDHDNSSCENTRAL_NERVOUS_SYSTEM335p.K341fsc.1021_1022delAAFrame_Shift_Del30.1142MGBAN008N
RB1LFLIMIKLFLUNG335p.L337fsc.1011_1011delGFrame_Shift_Del50.11COLO668N7014N
RB1LIMIKLFRLLUNG337p.L337fsc.1011_1011delGFrame_Shift_Del50.11COLO668N15024N
RB1LIPILTTAQLUNG400p.I401fsc.1202_1202delTFrame_Shift_Del50.11HCC33N0020N
RB1LSLFYKKCISOFT_TISSUE647p.K652fsc.1954_1954delAFrame_Shift_Del20.11SKUT1N11012N
RB1MIKLFRLILLUNG339p.L337fsc.1011_1011delGFrame_Shift_Del50.11COLO668Y10921N
RB1NLIPILTTALUNG399p.I401fsc.1202_1202delTFrame_Shift_Del50.11HCC33Y4110N
RB1NVYFKILYLENDOMETRIUM290p.K294fsc.880_880delAFrame_Shift_Del40.11ISHIKAWAHERAKLIO02ERY1790N
RB1PSENLIPILLUNG396p.I401fsc.1202_1202delTFrame_Shift_Del30.11HCC33N000N
RB1QPSENLIPILUNG395p.I401fsc.1202_1202delTFrame_Shift_Del20.11HCC33Y14110N
RB1RLFLDHDNSCENTRAL_NERVOUS_SYSTEM334p.K341fsc.1021_1022delAAFrame_Shift_Del20.1142MGBAN200N
RB1RLFLIMIKLLUNG334p.L337fsc.1011_1011delGFrame_Shift_Del40.11COLO668Y2390N
RB1SENLIPILTLUNG397p.I401fsc.1202_1202delTFrame_Shift_Del40.11HCC33N600N
RB1SLFYKKCIGSOFT_TISSUE648p.K652fsc.1954_1954delAFrame_Shift_Del30.11SKUT1N000N
RB1VKNVYFKILENDOMETRIUM288p.K294fsc.880_880delAFrame_Shift_Del20.11ISHIKAWAHERAKLIO02ERN802N
RB1VYFKILYLLENDOMETRIUM291p.K294fsc.880_880delAFrame_Shift_Del50.11ISHIKAWAHERAKLIO02ERY1496N
RB1CGWSIGRLYENDOMETRIUM83p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N600N
RB1CGWSIGRLYOVARY83p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N600N
RB1DHVRESLVNENDOMETRIUM68p.R71fsc.211_212delAGFrame_Shift_Del40.22COLO684N100N
RB1DHVRESLVNOVARY68p.R71fsc.211_212delAGFrame_Shift_Del40.22COLO704N100N
RB1EKGTVGNLYENDOMETRIUM94p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N300N
RB1EKGTVGNLYOVARY94p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N300N
RB1ESFICGWSIENDOMETRIUM79p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO684N600N
RB1ESFICGWSIOVARY79p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO704N600N
RB1ESLVNLGESENDOMETRIUM72p.R71fsc.211_212delAGFrame_Shift_Del40.22COLO684N200N
RB1ESLVNLGESOVARY72p.R71fsc.211_212delAGFrame_Shift_Del40.22COLO704N200N
RB1FICGWSIGRENDOMETRIUM81p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N803N
RB1FICGWSIGROVARY81p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N803N
RB1GESFICGWSENDOMETRIUM78p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO684N400N
RB1GESFICGWSOVARY78p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO704N400N
RB1GNLYLYCSSENDOMETRIUM99p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N100N
RB1GNLYLYCSSOVARY99p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N100N
RB1GRLYSKEKGENDOMETRIUM88p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N100N
RB1GRLYSKEKGOVARY88p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N100N
RB1GTVGNLYLYENDOMETRIUM96p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684Y8130N
RB1GTVGNLYLYOVARY96p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704Y8130N
RB1GWSIGRLYSENDOMETRIUM84p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N000N
RB1GWSIGRLYSOVARY84p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N000N
RB1HVRESLVNLENDOMETRIUM69p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO684Y7110N
RB1HVRESLVNLOVARY69p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO704Y7110N
RB1ICGWSIGRLENDOMETRIUM82p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N600N
RB1ICGWSIGRLOVARY82p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N600N
RB1IGRLYSKEKENDOMETRIUM87p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO684N002N
RB1IGRLYSKEKOVARY87p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO704N002N
RB1IPDHVRESLENDOMETRIUM66p.R71fsc.211_212delAGFrame_Shift_Del20.22COLO684Y17100Y
RB1IPDHVRESLOVARY66p.R71fsc.211_212delAGFrame_Shift_Del20.22COLO704Y17100Y
RB1KEKGTVGNLENDOMETRIUM93p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684Y9130N
RB1KEKGTVGNLOVARY93p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704Y9130N
RB1KGTVGNLYLENDOMETRIUM95p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N1000N
RB1KGTVGNLYLOVARY95p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N1000N
RB1LGESFICGWENDOMETRIUM77p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO684N300N
RB1LGESFICGWOVARY77p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO704N300N
RB1LVNLGESFIENDOMETRIUM74p.R71fsc.211_212delAGFrame_Shift_Del30.22COLO684Y9103N
RB1LVNLGESFIOVARY74p.R71fsc.211_212delAGFrame_Shift_Del30.22COLO704Y9103N
RB1LYSKEKGTVENDOMETRIUM90p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO684N305N
RB1LYSKEKGTVOVARY90p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO704N305N
RB1NLGESFICGENDOMETRIUM76p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO684N000N
RB1NLGESFICGOVARY76p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO704N000N
RB1PDHVRESLVENDOMETRIUM67p.R71fsc.211_212delAGFrame_Shift_Del30.22COLO684N100N
RB1PDHVRESLVOVARY67p.R71fsc.211_212delAGFrame_Shift_Del30.22COLO704N100N
RB1RESLVNLGEENDOMETRIUM71p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO684N000N
RB1RESLVNLGEOVARY71p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO704N000N
RB1RLYSKEKGTENDOMETRIUM89p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO684N400Y
RB1RLYSKEKGTOVARY89p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO704N400Y
RB1SFICGWSIGENDOMETRIUM80p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N000N
RB1SFICGWSIGOVARY80p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N000N
RB1SIGRLYSKEENDOMETRIUM86p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N000N
RB1SIGRLYSKEOVARY86p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N000N
RB1SKEKGTVGNENDOMETRIUM92p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N100N
RB1SKEKGTVGNOVARY92p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N100N
RB1SLVNLGESFENDOMETRIUM73p.R71fsc.211_212delAGFrame_Shift_Del30.22COLO684N400N
RB1SLVNLGESFOVARY73p.R71fsc.211_212delAGFrame_Shift_Del30.22COLO704N400N
RB1TVGNLYLYCENDOMETRIUM97p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N300N
RB1TVGNLYLYCOVARY97p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N300N
RB1VGNLYLYCSENDOMETRIUM98p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N008N
RB1VGNLYLYCSOVARY98p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N008N
RB1VNLGESFICENDOMETRIUM75p.R71fsc.211_212delAGFrame_Shift_Del40.22COLO684N006N
RB1VNLGESFICOVARY75p.R71fsc.211_212delAGFrame_Shift_Del40.22COLO704N006N
RB1VRESLVNLGENDOMETRIUM70p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO684N106N
RB1VRESLVNLGOVARY70p.R71fsc.211_212delAGFrame_Shift_Del50.22COLO704N106N
RB1WSIGRLYSKENDOMETRIUM85p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684Y5122N
RB1WSIGRLYSKOVARY85p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704Y5122N
RB1YSKEKGTVGENDOMETRIUM91p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO684N200Y
RB1YSKEKGTVGOVARY91p.R71fsc.211_212delAGFrame_Shift_Del60.22COLO704N200Y
RB1ALEVVMVHILUNG490p.A496fsc.1486_1487insTFrame_Shift_Ins30.11CPCNY6160N
RB1CALEVVMVHLUNG489p.A496fsc.1486_1487insTFrame_Shift_Ins20.11CPCNN000N
RB1TQPSSSIIYLUNG175p.I181fsc.541_542insTFrame_Shift_Ins20.11NCIH596N700N