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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
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Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NF2 | ACLSTSKIL | PLEURA | 501 | p.P486fs | c.1456_1465delCCAATTCCAG | Frame_Shift_Del | 6 | 0.11 | MPP89 | N | 12 | 0 | 0 | N | ||||||||||||
NF2 | AGIFGPRGI | LARGE_INTESTINE | 159 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 9 | 0 | 0 | N | ||||||||||||
NF2 | AQSCCLEWM | STOMACH | 229 | p.K227fs | c.679_679delA | Frame_Shift_Del | 6 | 0.11 | NUGC3 | N | 6 | 0 | 0 | N | ||||||||||||
NF2 | ASTSLVTAC | PLEURA | 494 | p.P486fs | c.1456_1465delCCAATTCCAG | Frame_Shift_Del | 6 | 0.11 | MPP89 | N | 1 | 0 | 0 | N | ||||||||||||
NF2 | CCLEWMPWG | STOMACH | 232 | p.K227fs | c.679_679delA | Frame_Shift_Del | 7 | 0.11 | NUGC3 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | CLEWMPWGF | STOMACH | 233 | p.K227fs | c.679_679delA | Frame_Shift_Del | 7 | 0.11 | NUGC3 | N | 5 | 0 | 0 | N | ||||||||||||
NF2 | CLLTYQAST | PLEURA | 488 | p.P486fs | c.1456_1465delCCAATTCCAG | Frame_Shift_Del | 6 | 0.11 | MPP89 | N | 5 | 0 | 0 | N | ||||||||||||
NF2 | CLVRRAPRP | LARGE_INTESTINE | 189 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | CSQAGIFGP | LARGE_INTESTINE | 156 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 7 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | DDSGNVGGE | LARGE_INTESTINE | 178 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | DPCSQAGIF | LARGE_INTESTINE | 154 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 11 | 0 | 0 | N | ||||||||||||
NF2 | DSGNVGGEN | LARGE_INTESTINE | 179 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | EWMPWGFTF | STOMACH | 235 | p.K227fs | c.679_679delA | Frame_Shift_Del | 6 | 0.11 | NUGC3 | N | 3 | 0 | 0 | N | ||||||||||||
NF2 | FRGMKSETS | LUNG | 256 | p.F256fs | c.768_768delC | Frame_Shift_Del | 6 | 0.11 | LOUNH91 | N | 3 | 0 | 35 | N | ||||||||||||
NF2 | FTFMTLRTD | STOMACH | 241 | p.K227fs | c.679_679delA | Frame_Shift_Del | 6 | 0.11 | NUGC3 | N | 2 | 0 | 8 | N | ||||||||||||
NF2 | GFTFMTLRT | STOMACH | 240 | p.K227fs | c.679_679delA | Frame_Shift_Del | 6 | 0.11 | NUGC3 | N | 1 | 0 | 0 | N | ||||||||||||
NF2 | GIFGPRGIA | LARGE_INTESTINE | 160 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 1 | 0 | 0 | N | ||||||||||||
NF2 | GNVGGENYC | LARGE_INTESTINE | 181 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | HRCLLTYQA | PLEURA | 486 | p.P486fs | c.1456_1465delCCAATTCCAG | Frame_Shift_Del | 6 | 0.11 | MPP89 | Y | 3 | 10 | 0 | N | ||||||||||||
NF2 | IFGPRGIAS | LARGE_INTESTINE | 161 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 0 | 0 | 0 | Y | ||||||||||||
NF2 | IKHWIRKLM | LARGE_INTESTINE | 273 | p.P275fs | c.823_823delC | Frame_Shift_Del | 6 | 0.11 | RKO | N | 5 | 0 | 11 | N | ||||||||||||
NF2 | KHWIRKLMS | LARGE_INTESTINE | 274 | p.P275fs | c.823_823delC | Frame_Shift_Del | 6 | 0.11 | RKO | N | 1 | 0 | 0 | N | ||||||||||||
NF2 | KSVSDDSGN | LARGE_INTESTINE | 174 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 1 | 0 | 0 | N | ||||||||||||
NF2 | LEWMPWGFT | STOMACH | 234 | p.K227fs | c.679_679delA | Frame_Shift_Del | 6 | 0.11 | NUGC3 | N | 7 | 0 | 0 | N | ||||||||||||
NF2 | LLLNHWIRK | LUNG | 271 | p.F256fs | c.768_768delC | Frame_Shift_Del | 6 | 0.11 | LOUNH91 | N | 6 | 0 | 0 | N | ||||||||||||
NF2 | LLNHWIRKL | LUNG | 272 | p.F256fs | c.768_768delC | Frame_Shift_Del | 6 | 0.11 | LOUNH91 | Y | 11 | 10 | 14 | N | ||||||||||||
NF2 | LNHWIRKLM | LUNG | 273 | p.F256fs | c.768_768delC | Frame_Shift_Del | 6 | 0.11 | LOUNH91 | N | 4 | 0 | 11 | N | ||||||||||||
NF2 | LVRRAPRPS | LARGE_INTESTINE | 190 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 0 | 0 | 28 | N | ||||||||||||
NF2 | LVTACLSTS | PLEURA | 498 | p.P486fs | c.1456_1465delCCAATTCCAG | Frame_Shift_Del | 6 | 0.11 | MPP89 | N | 0 | 0 | 17 | N | ||||||||||||
NF2 | MNHRCLLTY | PLEURA | 484 | p.P486fs | c.1456_1465delCCAATTCCAG | Frame_Shift_Del | 6 | 0.11 | MPP89 | N | 7 | 0 | 5 | N | ||||||||||||
NF2 | MPWGFTFMT | STOMACH | 237 | p.K227fs | c.679_679delA | Frame_Shift_Del | 6 | 0.11 | NUGC3 | Y | 9 | 9 | 0 | N | ||||||||||||
NF2 | NHWIRKLMS | LUNG | 274 | p.F256fs | c.768_768delC | Frame_Shift_Del | 6 | 0.11 | LOUNH91 | N | 1 | 0 | 0 | N | ||||||||||||
NF2 | NKRAQSCCL | STOMACH | 226 | p.K227fs | c.679_679delA | Frame_Shift_Del | 6 | 0.11 | NUGC3 | N | 3 | 0 | 0 | N | ||||||||||||
NF2 | NVGGENYCL | LARGE_INTESTINE | 182 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 6 | 0 | 0 | N | ||||||||||||
NF2 | NYCLVRRAP | LARGE_INTESTINE | 187 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | PCSQAGIFG | LARGE_INTESTINE | 155 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 7 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | PMNHRCLLT | PLEURA | 483 | p.P486fs | c.1456_1465delCCAATTCCAG | Frame_Shift_Del | 6 | 0.11 | MPP89 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | PWGFTFMTL | STOMACH | 238 | p.K227fs | c.679_679delA | Frame_Shift_Del | 6 | 0.11 | NUGC3 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | QAGIFGPRG | LARGE_INTESTINE | 158 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | QASTSLVTA | PLEURA | 493 | p.P486fs | c.1456_1465delCCAATTCCAG | Frame_Shift_Del | 6 | 0.11 | MPP89 | N | 3 | 0 | 0 | N | ||||||||||||
NF2 | QSCCLEWMP | STOMACH | 230 | p.K227fs | c.679_679delA | Frame_Shift_Del | 7 | 0.11 | NUGC3 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | RCLLTYQAS | PLEURA | 487 | p.P486fs | c.1456_1465delCCAATTCCAG | Frame_Shift_Del | 6 | 0.11 | MPP89 | N | 1 | 0 | 0 | N | ||||||||||||
NF2 | RGMKSETSR | LUNG | 257 | p.F256fs | c.768_768delC | Frame_Shift_Del | 6 | 0.11 | LOUNH91 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | RNKRAQSCC | STOMACH | 225 | p.K227fs | c.679_679delA | Frame_Shift_Del | 6 | 0.11 | NUGC3 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | RSLLLNHWI | LUNG | 269 | p.F256fs | c.768_768delC | Frame_Shift_Del | 6 | 0.11 | LOUNH91 | Y | 9 | 13 | 0 | N | ||||||||||||
NF2 | SCCLEWMPW | STOMACH | 231 | p.K227fs | c.679_679delA | Frame_Shift_Del | 7 | 0.11 | NUGC3 | N | 2 | 0 | 0 | N | ||||||||||||
NF2 | SDDSGNVGG | LARGE_INTESTINE | 177 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | SGNVGGENY | LARGE_INTESTINE | 180 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 5 | 0 | 0 | N | ||||||||||||
NF2 | SKKGNKSVS | LARGE_INTESTINE | 169 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 1 | 0 | 0 | N | ||||||||||||
NF2 | SLLLNHWIR | LUNG | 270 | p.F256fs | c.768_768delC | Frame_Shift_Del | 6 | 0.11 | LOUNH91 | Y | 6 | 11 | 0 | N | ||||||||||||
NF2 | SQAGIFGPR | LARGE_INTESTINE | 157 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 5 | 0 | 0 | N | ||||||||||||
NF2 | TRSLLLNHW | LUNG | 268 | p.F256fs | c.768_768delC | Frame_Shift_Del | 6 | 0.11 | LOUNH91 | Y | 2 | 9 | 0 | N | ||||||||||||
NF2 | VGGENYCLV | LARGE_INTESTINE | 183 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | Y | 10 | 11 | 0 | N | ||||||||||||
NF2 | VSDDSGNVG | LARGE_INTESTINE | 176 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 1 | 0 | 0 | N | ||||||||||||
NF2 | WGFTFMTLR | STOMACH | 239 | p.K227fs | c.679_679delA | Frame_Shift_Del | 6 | 0.11 | NUGC3 | N | 4 | 0 | 2 | N | ||||||||||||
NF2 | WMPWGFTFM | STOMACH | 236 | p.K227fs | c.679_679delA | Frame_Shift_Del | 6 | 0.11 | NUGC3 | Y | 14 | 9 | 0 | N | ||||||||||||
NF2 | YCLVRRAPR | LARGE_INTESTINE | 188 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 6 | 0 | 8 | N | ||||||||||||
NF2 | YDPCSQAGI | LARGE_INTESTINE | 153 | p.P155fs | c.465_466delCA | Frame_Shift_Del | 6 | 0.11 | SNUC4 | N | 7 | 0 | 0 | N | ||||||||||||
NF2 | YQASTSLVT | PLEURA | 492 | p.P486fs | c.1456_1465delCCAATTCCAG | Frame_Shift_Del | 6 | 0.11 | MPP89 | N | 6 | 0 | 5 | N | ||||||||||||
NF2 | HWIRKLMSS | LUNG | 275 | p.F256fs | c.768_768delC | Frame_Shift_Del | 6 | 0.22 | LOUNH91 | N | 0 | 0 | 0 | N | ||||||||||||
NF2 | HWIRKLMSS | LARGE_INTESTINE | 275 | p.P275fs | c.823_823delC | Frame_Shift_Del | 6 | 0.22 | RKO | N | 0 | 0 | 0 | N | ||||||||||||