Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
NF2ACLSTSKILPLEURA501p.P486fsc.1456_1465delCCAATTCCAGFrame_Shift_Del60.11MPP89N1200N
NF2AGIFGPRGILARGE_INTESTINE159p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N900N
NF2AQSCCLEWMSTOMACH229p.K227fsc.679_679delAFrame_Shift_Del60.11NUGC3N600N
NF2ASTSLVTACPLEURA494p.P486fsc.1456_1465delCCAATTCCAGFrame_Shift_Del60.11MPP89N100N
NF2CCLEWMPWGSTOMACH232p.K227fsc.679_679delAFrame_Shift_Del70.11NUGC3N000N
NF2CLEWMPWGFSTOMACH233p.K227fsc.679_679delAFrame_Shift_Del70.11NUGC3N500N
NF2CLLTYQASTPLEURA488p.P486fsc.1456_1465delCCAATTCCAGFrame_Shift_Del60.11MPP89N500N
NF2CLVRRAPRPLARGE_INTESTINE189p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N000N
NF2CSQAGIFGPLARGE_INTESTINE156p.P155fsc.465_466delCAFrame_Shift_Del70.11SNUC4N000N
NF2DDSGNVGGELARGE_INTESTINE178p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N000N
NF2DPCSQAGIFLARGE_INTESTINE154p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N1100N
NF2DSGNVGGENLARGE_INTESTINE179p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N000N
NF2EWMPWGFTFSTOMACH235p.K227fsc.679_679delAFrame_Shift_Del60.11NUGC3N300N
NF2FRGMKSETSLUNG256p.F256fsc.768_768delCFrame_Shift_Del60.11LOUNH91N3035N
NF2FTFMTLRTDSTOMACH241p.K227fsc.679_679delAFrame_Shift_Del60.11NUGC3N208N
NF2GFTFMTLRTSTOMACH240p.K227fsc.679_679delAFrame_Shift_Del60.11NUGC3N100N
NF2GIFGPRGIALARGE_INTESTINE160p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N100N
NF2GNVGGENYCLARGE_INTESTINE181p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N000N
NF2HRCLLTYQAPLEURA486p.P486fsc.1456_1465delCCAATTCCAGFrame_Shift_Del60.11MPP89Y3100N
NF2IFGPRGIASLARGE_INTESTINE161p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N000Y
NF2IKHWIRKLMLARGE_INTESTINE273p.P275fsc.823_823delCFrame_Shift_Del60.11RKON5011N
NF2KHWIRKLMSLARGE_INTESTINE274p.P275fsc.823_823delCFrame_Shift_Del60.11RKON100N
NF2KSVSDDSGNLARGE_INTESTINE174p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N100N
NF2LEWMPWGFTSTOMACH234p.K227fsc.679_679delAFrame_Shift_Del60.11NUGC3N700N
NF2LLLNHWIRKLUNG271p.F256fsc.768_768delCFrame_Shift_Del60.11LOUNH91N600N
NF2LLNHWIRKLLUNG272p.F256fsc.768_768delCFrame_Shift_Del60.11LOUNH91Y111014N
NF2LNHWIRKLMLUNG273p.F256fsc.768_768delCFrame_Shift_Del60.11LOUNH91N4011N
NF2LVRRAPRPSLARGE_INTESTINE190p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N0028N
NF2LVTACLSTSPLEURA498p.P486fsc.1456_1465delCCAATTCCAGFrame_Shift_Del60.11MPP89N0017N
NF2MNHRCLLTYPLEURA484p.P486fsc.1456_1465delCCAATTCCAGFrame_Shift_Del60.11MPP89N705N
NF2MPWGFTFMTSTOMACH237p.K227fsc.679_679delAFrame_Shift_Del60.11NUGC3Y990N
NF2NHWIRKLMSLUNG274p.F256fsc.768_768delCFrame_Shift_Del60.11LOUNH91N100N
NF2NKRAQSCCLSTOMACH226p.K227fsc.679_679delAFrame_Shift_Del60.11NUGC3N300N
NF2NVGGENYCLLARGE_INTESTINE182p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N600N
NF2NYCLVRRAPLARGE_INTESTINE187p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N000N
NF2PCSQAGIFGLARGE_INTESTINE155p.P155fsc.465_466delCAFrame_Shift_Del70.11SNUC4N000N
NF2PMNHRCLLTPLEURA483p.P486fsc.1456_1465delCCAATTCCAGFrame_Shift_Del60.11MPP89N000N
NF2PWGFTFMTLSTOMACH238p.K227fsc.679_679delAFrame_Shift_Del60.11NUGC3N000N
NF2QAGIFGPRGLARGE_INTESTINE158p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N000N
NF2QASTSLVTAPLEURA493p.P486fsc.1456_1465delCCAATTCCAGFrame_Shift_Del60.11MPP89N300N
NF2QSCCLEWMPSTOMACH230p.K227fsc.679_679delAFrame_Shift_Del70.11NUGC3N000N
NF2RCLLTYQASPLEURA487p.P486fsc.1456_1465delCCAATTCCAGFrame_Shift_Del60.11MPP89N100N
NF2RGMKSETSRLUNG257p.F256fsc.768_768delCFrame_Shift_Del60.11LOUNH91N000N
NF2RNKRAQSCCSTOMACH225p.K227fsc.679_679delAFrame_Shift_Del60.11NUGC3N000N
NF2RSLLLNHWILUNG269p.F256fsc.768_768delCFrame_Shift_Del60.11LOUNH91Y9130N
NF2SCCLEWMPWSTOMACH231p.K227fsc.679_679delAFrame_Shift_Del70.11NUGC3N200N
NF2SDDSGNVGGLARGE_INTESTINE177p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N000N
NF2SGNVGGENYLARGE_INTESTINE180p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N500N
NF2SKKGNKSVSLARGE_INTESTINE169p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N100N
NF2SLLLNHWIRLUNG270p.F256fsc.768_768delCFrame_Shift_Del60.11LOUNH91Y6110N
NF2SQAGIFGPRLARGE_INTESTINE157p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N500N
NF2TRSLLLNHWLUNG268p.F256fsc.768_768delCFrame_Shift_Del60.11LOUNH91Y290N
NF2VGGENYCLVLARGE_INTESTINE183p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4Y10110N
NF2VSDDSGNVGLARGE_INTESTINE176p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N100N
NF2WGFTFMTLRSTOMACH239p.K227fsc.679_679delAFrame_Shift_Del60.11NUGC3N402N
NF2WMPWGFTFMSTOMACH236p.K227fsc.679_679delAFrame_Shift_Del60.11NUGC3Y1490N
NF2YCLVRRAPRLARGE_INTESTINE188p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N608N
NF2YDPCSQAGILARGE_INTESTINE153p.P155fsc.465_466delCAFrame_Shift_Del60.11SNUC4N700N
NF2YQASTSLVTPLEURA492p.P486fsc.1456_1465delCCAATTCCAGFrame_Shift_Del60.11MPP89N605N
NF2HWIRKLMSSLUNG275p.F256fsc.768_768delCFrame_Shift_Del60.22LOUNH91N000N
NF2HWIRKLMSSLARGE_INTESTINE275p.P275fsc.823_823delCFrame_Shift_Del60.22RKON000N