Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
METANLGHQRVASTOMACH453p.G456fsc.1366_1366delGFrame_Shift_Del50.11MKN74N100N
METASCRLWFLDSTOMACH461p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N000N
METCRLWFLDQDSTOMACH463p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N100N
METDVYLSSEILLARGE_INTESTINE236p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N1000N
METEILTPLSMSLARGE_INTESTINE242p.V237fsc.710_710delTFrame_Shift_Del60.11HCT116N100N
METFLDQDHQPLSTOMACH467p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N1400N
METGHQRVASCRSTOMACH456p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N100N
METHQRVASCRLSTOMACH457p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N800N
METIANLGHQRVSTOMACH452p.G456fsc.1366_1366delGFrame_Shift_Del40.11MKN74N500N
METIDVYLSSEILARGE_INTESTINE235p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N702N
METILTPLSMSMLARGE_INTESTINE243p.V237fsc.710_710delTFrame_Shift_Del60.11HCT116N700N
METLDQDHQPLMSTOMACH468p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N500N
METLGHQRVASCSTOMACH455p.G456fsc.1366_1366delGFrame_Shift_Del50.11MKN74N105N
METLKATILFTSLARGE_INTESTINE253p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N100N
METLSMSMPLKALARGE_INTESTINE247p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N4011N
METLSSEILTPLLARGE_INTESTINE239p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N1600N
METLTPLSMSMPLARGE_INTESTINE244p.V237fsc.710_710delTFrame_Shift_Del60.11HCT116N000N
METLWFLDQDHQSTOMACH465p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N000N
METMPLKATILFLARGE_INTESTINE251p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N1304N
METMSMPLKATILARGE_INTESTINE249p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N900N
METNLGHQRVASSTOMACH454p.G456fsc.1366_1366delGFrame_Shift_Del50.11MKN74N000N
METPLKATILFTLARGE_INTESTINE252p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N000N
METPLSMSMPLKLARGE_INTESTINE246p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N100N
METQRVASCRLWSTOMACH458p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N200N
METQSYIDVYLSLARGE_INTESTINE232p.V237fsc.710_710delTFrame_Shift_Del30.11HCT116N000N
METRLWFLDQDHSTOMACH464p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N200N
METRVASCRLWFSTOMACH459p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74Y5100N
METSCRLWFLDQSTOMACH462p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N000N
METSEILTPLSMLARGE_INTESTINE241p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N700N
METSMPLKATILLARGE_INTESTINE250p.V237fsc.710_710delTFrame_Shift_Del60.11HCT116N1300N
METSMSMPLKATLARGE_INTESTINE248p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N200N
METSSEILTPLSLARGE_INTESTINE240p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N100N
METSYIDVYLSSLARGE_INTESTINE233p.V237fsc.710_710delTFrame_Shift_Del40.11HCT116N300N
METTIANLGHQRSTOMACH451p.G456fsc.1366_1366delGFrame_Shift_Del30.11MKN74N400N
METTPLSMSMPLLARGE_INTESTINE245p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N2100N
METVASCRLWFLSTOMACH460p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74Y18100N
METVYLSSEILTLARGE_INTESTINE237p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N300N
METWFLDQDHQPSTOMACH466p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N200N
METYIDVYLSSELARGE_INTESTINE234p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N200N
METYLSSEILTPLARGE_INTESTINE238p.V237fsc.710_710delTFrame_Shift_Del50.11HCT116N305N