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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
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Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FBXW7 | AVLEMPLLG | ENDOMETRIUM | 476 | p.R473fs | c.1417_1417delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | EMPLLGFGI | ENDOMETRIUM | 479 | p.R473fs | c.1417_1417delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 9 | 0 | 0 | N | ||||||||||||
FBXW7 | ILRQASVYM | ENDOMETRIUM | 487 | p.R473fs | c.1417_1417delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | Y | 7 | 10 | 17 | N | ||||||||||||
FBXW7 | LEMPLLGFG | ENDOMETRIUM | 478 | p.R473fs | c.1417_1417delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 2 | 0 | 0 | N | ||||||||||||
FBXW7 | LRQASVYMF | ENDOMETRIUM | 488 | p.R473fs | c.1417_1417delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | Y | 5 | 10 | 27 | N | ||||||||||||
FBXW7 | MPLLGFGIL | ENDOMETRIUM | 480 | p.R473fs | c.1417_1417delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 23 | 0 | 0 | N | ||||||||||||
FBXW7 | VLEMPLLGF | ENDOMETRIUM | 477 | p.R473fs | c.1417_1417delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 6 | 0 | 2 | N | ||||||||||||
FBXW7 | CWCWTLMWT | LARGE_INTESTINE | 697 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 7 | 0.22 | SNUC5 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | CWCWTLMWT | LARGE_INTESTINE | 697 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 7 | 0.22 | SW48 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | GLKKPSCWC | LARGE_INTESTINE | 691 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SNUC5 | N | 2 | 0 | 0 | N | ||||||||||||
FBXW7 | GLKKPSCWC | LARGE_INTESTINE | 691 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SW48 | N | 2 | 0 | 0 | N | ||||||||||||
FBXW7 | KKPSCWCWT | LARGE_INTESTINE | 693 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SNUC5 | N | 2 | 0 | 0 | N | ||||||||||||
FBXW7 | KKPSCWCWT | LARGE_INTESTINE | 693 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SW48 | N | 2 | 0 | 0 | N | ||||||||||||
FBXW7 | KPSCWCWTL | LARGE_INTESTINE | 694 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SNUC5 | Y | 19 | 9 | 0 | N | ||||||||||||
FBXW7 | KPSCWCWTL | LARGE_INTESTINE | 694 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SW48 | Y | 19 | 9 | 0 | N | ||||||||||||
FBXW7 | LKKPSCWCW | LARGE_INTESTINE | 692 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SNUC5 | N | 4 | 0 | 0 | N | ||||||||||||
FBXW7 | LKKPSCWCW | LARGE_INTESTINE | 692 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SW48 | N | 4 | 0 | 0 | N | ||||||||||||
FBXW7 | MGLKKPSCW | LARGE_INTESTINE | 690 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SNUC5 | N | 3 | 0 | 5 | N | ||||||||||||
FBXW7 | MGLKKPSCW | LARGE_INTESTINE | 690 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SW48 | N | 3 | 0 | 5 | N | ||||||||||||
FBXW7 | PQTQSWCVQ | LARGE_INTESTINE | 677 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SNUC5 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | PQTQSWCVQ | LARGE_INTESTINE | 677 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SW48 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | PSCWCWTLM | LARGE_INTESTINE | 695 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SNUC5 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | PSCWCWTLM | LARGE_INTESTINE | 695 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SW48 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | SCWCWTLMW | LARGE_INTESTINE | 696 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 7 | 0.22 | SNUC5 | N | 5 | 0 | 0 | N | ||||||||||||
FBXW7 | SCWCWTLMW | LARGE_INTESTINE | 696 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 7 | 0.22 | SW48 | N | 5 | 0 | 0 | N | ||||||||||||
FBXW7 | TQSWCVQLG | LARGE_INTESTINE | 679 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SNUC5 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | TQSWCVQLG | LARGE_INTESTINE | 679 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SW48 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | WCVQLGVGM | LARGE_INTESTINE | 682 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SNUC5 | N | 7 | 0 | 1 | N | ||||||||||||
FBXW7 | WCVQLGVGM | LARGE_INTESTINE | 682 | p.G667fs | c.2001_2001delG | Frame_Shift_Del | 6 | 0.22 | SW48 | N | 7 | 0 | 1 | N | ||||||||||||
FBXW7 | ENISGTYRW | LARGE_INTESTINE | 415 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | Y | 2 | 17 | 0 | N | ||||||||||||
FBXW7 | GTYRWSMVI | LARGE_INTESTINE | 419 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 13 | 0 | 0 | N | ||||||||||||
FBXW7 | ISGTYRWSM | LARGE_INTESTINE | 417 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 5 | 0 | 0 | N | ||||||||||||
FBXW7 | ITNERQHHH | LARGE_INTESTINE | 427 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | Y | 0 | 10 | 0 | N | ||||||||||||
FBXW7 | LVSSHRQMS | LARGE_INTESTINE | 406 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 0 | 0 | 25 | N | ||||||||||||
FBXW7 | MVITNERQH | LARGE_INTESTINE | 425 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 2 | 0 | 9 | N | ||||||||||||
FBXW7 | NISGTYRWS | LARGE_INTESTINE | 416 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 1 | 0 | 0 | N | ||||||||||||
FBXW7 | NTFKSLVSS | LARGE_INTESTINE | 401 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 1 | 0 | 0 | N | ||||||||||||
FBXW7 | RWSMVITNE | LARGE_INTESTINE | 422 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | SMVITNERQ | LARGE_INTESTINE | 424 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | TFKSLVSSH | LARGE_INTESTINE | 402 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | TYRWSMVIT | LARGE_INTESTINE | 420 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | Y | 1 | 11 | 0 | N | ||||||||||||
FBXW7 | VITNERQHH | LARGE_INTESTINE | 426 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 0 | 0 | 9 | N | ||||||||||||
FBXW7 | VSSHRQMSE | LARGE_INTESTINE | 407 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 0 | 0 | 0 | N | ||||||||||||
FBXW7 | WSMVITNER | LARGE_INTESTINE | 423 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 5 | 0 | 10 | N | ||||||||||||
FBXW7 | YRWSMVITN | LARGE_INTESTINE | 421 | p.L403fs | c.1208_1209insT | Frame_Shift_Ins | 6 | 0.11 | SW837 | N | 5 | 0 | 15 | N | ||||||||||||