Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
FBXW7AVLEMPLLGENDOMETRIUM476p.R473fsc.1417_1417delAFrame_Shift_Del60.11HEC108N000N
FBXW7EMPLLGFGIENDOMETRIUM479p.R473fsc.1417_1417delAFrame_Shift_Del60.11HEC108N900N
FBXW7ILRQASVYMENDOMETRIUM487p.R473fsc.1417_1417delAFrame_Shift_Del60.11HEC108Y71017N
FBXW7LEMPLLGFGENDOMETRIUM478p.R473fsc.1417_1417delAFrame_Shift_Del60.11HEC108N200N
FBXW7LRQASVYMFENDOMETRIUM488p.R473fsc.1417_1417delAFrame_Shift_Del60.11HEC108Y51027N
FBXW7MPLLGFGILENDOMETRIUM480p.R473fsc.1417_1417delAFrame_Shift_Del60.11HEC108N2300N
FBXW7VLEMPLLGFENDOMETRIUM477p.R473fsc.1417_1417delAFrame_Shift_Del60.11HEC108N602N
FBXW7CWCWTLMWTLARGE_INTESTINE697p.G667fsc.2001_2001delGFrame_Shift_Del70.22SNUC5N000N
FBXW7CWCWTLMWTLARGE_INTESTINE697p.G667fsc.2001_2001delGFrame_Shift_Del70.22SW48N000N
FBXW7GLKKPSCWCLARGE_INTESTINE691p.G667fsc.2001_2001delGFrame_Shift_Del60.22SNUC5N200N
FBXW7GLKKPSCWCLARGE_INTESTINE691p.G667fsc.2001_2001delGFrame_Shift_Del60.22SW48N200N
FBXW7KKPSCWCWTLARGE_INTESTINE693p.G667fsc.2001_2001delGFrame_Shift_Del60.22SNUC5N200N
FBXW7KKPSCWCWTLARGE_INTESTINE693p.G667fsc.2001_2001delGFrame_Shift_Del60.22SW48N200N
FBXW7KPSCWCWTLLARGE_INTESTINE694p.G667fsc.2001_2001delGFrame_Shift_Del60.22SNUC5Y1990N
FBXW7KPSCWCWTLLARGE_INTESTINE694p.G667fsc.2001_2001delGFrame_Shift_Del60.22SW48Y1990N
FBXW7LKKPSCWCWLARGE_INTESTINE692p.G667fsc.2001_2001delGFrame_Shift_Del60.22SNUC5N400N
FBXW7LKKPSCWCWLARGE_INTESTINE692p.G667fsc.2001_2001delGFrame_Shift_Del60.22SW48N400N
FBXW7MGLKKPSCWLARGE_INTESTINE690p.G667fsc.2001_2001delGFrame_Shift_Del60.22SNUC5N305N
FBXW7MGLKKPSCWLARGE_INTESTINE690p.G667fsc.2001_2001delGFrame_Shift_Del60.22SW48N305N
FBXW7PQTQSWCVQLARGE_INTESTINE677p.G667fsc.2001_2001delGFrame_Shift_Del60.22SNUC5N000N
FBXW7PQTQSWCVQLARGE_INTESTINE677p.G667fsc.2001_2001delGFrame_Shift_Del60.22SW48N000N
FBXW7PSCWCWTLMLARGE_INTESTINE695p.G667fsc.2001_2001delGFrame_Shift_Del60.22SNUC5N000N
FBXW7PSCWCWTLMLARGE_INTESTINE695p.G667fsc.2001_2001delGFrame_Shift_Del60.22SW48N000N
FBXW7SCWCWTLMWLARGE_INTESTINE696p.G667fsc.2001_2001delGFrame_Shift_Del70.22SNUC5N500N
FBXW7SCWCWTLMWLARGE_INTESTINE696p.G667fsc.2001_2001delGFrame_Shift_Del70.22SW48N500N
FBXW7TQSWCVQLGLARGE_INTESTINE679p.G667fsc.2001_2001delGFrame_Shift_Del60.22SNUC5N000N
FBXW7TQSWCVQLGLARGE_INTESTINE679p.G667fsc.2001_2001delGFrame_Shift_Del60.22SW48N000N
FBXW7WCVQLGVGMLARGE_INTESTINE682p.G667fsc.2001_2001delGFrame_Shift_Del60.22SNUC5N701N
FBXW7WCVQLGVGMLARGE_INTESTINE682p.G667fsc.2001_2001delGFrame_Shift_Del60.22SW48N701N
FBXW7ENISGTYRWLARGE_INTESTINE415p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837Y2170N
FBXW7GTYRWSMVILARGE_INTESTINE419p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N1300N
FBXW7ISGTYRWSMLARGE_INTESTINE417p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N500N
FBXW7ITNERQHHHLARGE_INTESTINE427p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837Y0100N
FBXW7LVSSHRQMSLARGE_INTESTINE406p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N0025N
FBXW7MVITNERQHLARGE_INTESTINE425p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N209N
FBXW7NISGTYRWSLARGE_INTESTINE416p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N100N
FBXW7NTFKSLVSSLARGE_INTESTINE401p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N100N
FBXW7RWSMVITNELARGE_INTESTINE422p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N000N
FBXW7SMVITNERQLARGE_INTESTINE424p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N000N
FBXW7TFKSLVSSHLARGE_INTESTINE402p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N000N
FBXW7TYRWSMVITLARGE_INTESTINE420p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837Y1110N
FBXW7VITNERQHHLARGE_INTESTINE426p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N009N
FBXW7VSSHRQMSELARGE_INTESTINE407p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N000N
FBXW7WSMVITNERLARGE_INTESTINE423p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N5010N
FBXW7YRWSMVITNLARGE_INTESTINE421p.L403fsc.1208_1209insTFrame_Shift_Ins60.11SW837N5015N