Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
EGFRATQSACLRPLARGE_INTESTINE558p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2N000N
EGFRAYSATQSACLARGE_INTESTINE555p.E543fsc.1629_1629delGFrame_Shift_Del60.11CW2N200N
EGFRCNLLEVSQGLARGE_INTESTINE539p.E543fsc.1629_1629delGFrame_Shift_Del40.11CW2N000N
EGFRCRGIMIFPSOESOPHAGUS70p.T68fsc.203_203delCFrame_Shift_Del50.11KYSE70N200N
EGFREITMCRGIMOESOPHAGUS66p.T68fsc.203_203delCFrame_Shift_Del50.11KYSE70N200N
EGFREVSQGSLWRLARGE_INTESTINE543p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2Y590Y
EGFRGSLWRTLSALARGE_INTESTINE547p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2N300Y
EGFRITMCRGIMIOESOPHAGUS67p.T68fsc.203_203delCFrame_Shift_Del50.11KYSE70Y9158N
EGFRLEITMCRGIOESOPHAGUS65p.T68fsc.203_203delCFrame_Shift_Del50.11KYSE70N807N
EGFRLEVSQGSLWLARGE_INTESTINE542p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2N800N
EGFRLLEVSQGSLLARGE_INTESTINE541p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2N900N
EGFRLSAYSATQSLARGE_INTESTINE553p.E543fsc.1629_1629delGFrame_Shift_Del40.11CW2N001N
EGFRLWRTLSAYSLARGE_INTESTINE549p.E543fsc.1629_1629delGFrame_Shift_Del40.11CW2N004Y
EGFRMCRGIMIFPOESOPHAGUS69p.T68fsc.203_203delCFrame_Shift_Del50.11KYSE70N000N
EGFRNLEITMCRGOESOPHAGUS64p.T68fsc.203_203delCFrame_Shift_Del40.11KYSE70N100N
EGFRNLLEVSQGSLARGE_INTESTINE540p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2N000N
EGFRQGSLWRTLSLARGE_INTESTINE546p.E543fsc.1629_1629delGFrame_Shift_Del60.11CW2N000Y
EGFRRTLSAYSATLARGE_INTESTINE551p.E543fsc.1629_1629delGFrame_Shift_Del40.11CW2N200N
EGFRSATQSACLRLARGE_INTESTINE557p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2N300N
EGFRSAYSATQSALARGE_INTESTINE554p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2N400N
EGFRSLWRTLSAYLARGE_INTESTINE548p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2Y7150Y
EGFRSQGSLWRTLLARGE_INTESTINE545p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2Y8120N
EGFRTLSAYSATQLARGE_INTESTINE552p.E543fsc.1629_1629delGFrame_Shift_Del40.11CW2N100N
EGFRTMCRGIMIFOESOPHAGUS68p.T68fsc.203_203delCFrame_Shift_Del50.11KYSE70Y690N
EGFRVSQGSLWRTLARGE_INTESTINE544p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2N100Y
EGFRWRTLSAYSALARGE_INTESTINE550p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2N5024N
EGFRYSATQSACLLARGE_INTESTINE556p.E543fsc.1629_1629delGFrame_Shift_Del50.11CW2N1102N