Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
CBLCLGSEARSVLUNG634p.M628fsc.1883_1883delTFrame_Shift_Del50.11VMRCLCPY390N
CBLDQMCLGSEALUNG631p.M628fsc.1883_1883delTFrame_Shift_Del50.11VMRCLCPN100N
CBLEARSVWIPPLUNG638p.M628fsc.1883_1883delTFrame_Shift_Del60.11VMRCLCPN000N
CBLGSEARSVWILUNG636p.M628fsc.1883_1883delTFrame_Shift_Del60.11VMRCLCPN400N
CBLGSGARVRVASTOMACH16p.G18fsc.52_52delGFrame_Shift_Del50.112313287Y1110N
CBLLGSEARSVWLUNG635p.M628fsc.1883_1883delTFrame_Shift_Del60.11VMRCLCPN300N
CBLMCLGSEARSLUNG633p.M628fsc.1883_1883delTFrame_Shift_Del50.11VMRCLCPN000N
CBLPSQRSPDQMLUNG625p.M628fsc.1883_1883delTFrame_Shift_Del50.11VMRCLCPN000N
CBLQMCLGSEARLUNG632p.M628fsc.1883_1883delTFrame_Shift_Del60.11VMRCLCPN600N
CBLQRSPDQMCLLUNG627p.M628fsc.1883_1883delTFrame_Shift_Del50.11VMRCLCPN600N
CBLRSPDQMCLGLUNG628p.M628fsc.1883_1883delTFrame_Shift_Del50.11VMRCLCPN000N
CBLSEARSVWIPLUNG637p.M628fsc.1883_1883delTFrame_Shift_Del60.11VMRCLCPN100N
CBLSGSGARVRVSTOMACH15p.G18fsc.52_52delGFrame_Shift_Del50.112313287Y4100N
CBLSQRSPDQMCLUNG626p.M628fsc.1883_1883delTFrame_Shift_Del50.11VMRCLCPN200N