Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PIK3C2G | AADVLGRSG | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 261 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 3 | 0.11 | MOLM13 | N | 0 | 0 | 0 | N | ||||||||||||
| PIK3C2G | ADVLGRSGA | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 262 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 4 | 0.11 | MOLM13 | N | 4 | 0 | 0 | N | ||||||||||||
| PIK3C2G | ALLQHFRIS | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 270 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | N | 0 | 0 | 0 | N | ||||||||||||
| PIK3C2G | ALRPVHMLN | OVARY | 1357 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 1 | 0 | 0 | N | ||||||||||||
| PIK3C2G | CHVLIILSK | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 301 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | N | 0 | 0 | 0 | N | ||||||||||||
| PIK3C2G | CLSKEKTKD | OVARY | 957 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 5 | 0.11 | EFO27 | N | 0 | 0 | 0 | N | ||||||||||||
| PIK3C2G | DVLGRSGAL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 263 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | N | 11 | 0 | 0 | N | ||||||||||||
| PIK3C2G | DWCRWYLML | OVARY | 965 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 6 | 0.11 | EFO27 | N | 8 | 0 | 0 | N | ||||||||||||
| PIK3C2G | EKTKDWCRW | OVARY | 961 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 6 | 0.11 | EFO27 | N | 1 | 0 | 0 | N | ||||||||||||
| PIK3C2G | ERYHAADVL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 257 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 1 | 0.11 | MOLM13 | Y | 7 | 9 | 0 | N | ||||||||||||
| PIK3C2G | FIFYHIPVK | OVARY | 1366 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 7 | 0 | 11 | N | ||||||||||||
| PIK3C2G | FILCHVLII | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 298 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 6 | 0.11 | MOLM13 | Y | 14 | 10 | 49 | N | ||||||||||||
| PIK3C2G | FLLITQHNL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 289 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 4 | 0.11 | MOLM13 | Y | 17 | 10 | 11 | N | ||||||||||||
| PIK3C2G | FLRPSLIYI | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 280 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | Y | 12 | 14 | 3 | N | ||||||||||||
| PIK3C2G | FQNVRTPLT | OVARY | 1383 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 5 | 0.11 | IGROV1 | N | 6 | 0 | 9 | Y | ||||||||||||
| PIK3C2G | FRISSFLRP | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 275 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | N | 3 | 0 | 12 | N | ||||||||||||
| PIK3C2G | FVGGKQNLF | OVARY | 1375 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 6 | 0 | 1 | Y | ||||||||||||
| PIK3C2G | FYHIPVKFV | OVARY | 1368 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | Y | 7 | 11 | 12 | N | ||||||||||||
| PIK3C2G | GALLQHFRI | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 269 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | Y | 8 | 11 | 0 | N | ||||||||||||
| PIK3C2G | GGKQNLFQN | OVARY | 1377 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 5 | 0.11 | IGROV1 | N | 1 | 0 | 0 | N | ||||||||||||
| PIK3C2G | GKQNLFQNV | OVARY | 1378 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 5 | 0.11 | IGROV1 | N | 2 | 0 | 0 | N | ||||||||||||
| PIK3C2G | GRSGALLQH | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 266 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 6 | 0.11 | MOLM13 | N | 2 | 0 | 0 | N | ||||||||||||
| PIK3C2G | HAADVLGRS | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 260 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 3 | 0.11 | MOLM13 | N | 1 | 0 | 0 | N | ||||||||||||
| PIK3C2G | HFRISSFLR | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 274 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 6 | 0.11 | MOLM13 | N | 2 | 0 | 0 | N | ||||||||||||
| PIK3C2G | HIPVKFVGG | OVARY | 1370 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 0 | 0 | 0 | N | ||||||||||||
| PIK3C2G | HMKNISQMA | OVARY | 1349 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 4 | 0.11 | IGROV1 | N | 1 | 0 | 0 | N | ||||||||||||
| PIK3C2G | HMLNFIFYH | OVARY | 1362 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | Y | 3 | 9 | 0 | N | ||||||||||||
| PIK3C2G | HNLFILCHV | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 295 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 6 | 0.11 | MOLM13 | Y | 3 | 16 | 0 | N | ||||||||||||
| PIK3C2G | HVLIILSKI | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 302 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | Y | 11 | 12 | 0 | N | ||||||||||||
| PIK3C2G | IFLLITQHN | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 288 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 4 | 0.11 | MOLM13 | N | 0 | 0 | 12 | N | ||||||||||||
| PIK3C2G | IFYHIPVKF | OVARY | 1367 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | Y | 9 | 10 | 15 | N | ||||||||||||
| PIK3C2G | IIYRCLSKE | OVARY | 953 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 2 | 0.11 | EFO27 | N | 0 | 0 | 5 | N | ||||||||||||
| PIK3C2G | ILCHVLIIL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 299 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | Y | 13 | 11 | 5 | N | ||||||||||||
| PIK3C2G | IPVKFVGGK | OVARY | 1371 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 5 | 0.11 | IGROV1 | N | 5 | 0 | 2 | N | ||||||||||||
| PIK3C2G | ISQMALRPV | OVARY | 1353 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 6 | 0.11 | IGROV1 | N | 4 | 0 | 0 | N | ||||||||||||
| PIK3C2G | ISSFLRPSL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 277 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | N | 11 | 0 | 2 | Y | ||||||||||||
| PIK3C2G | ITQHNLFIL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 292 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 6 | 0.11 | MOLM13 | Y | 13 | 11 | 1 | N | ||||||||||||
| PIK3C2G | IYIFLLITQ | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 286 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | N | 0 | 0 | 37 | N | ||||||||||||
| PIK3C2G | IYRCLSKEK | OVARY | 954 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 2 | 0.11 | EFO27 | N | 1 | 0 | 3 | N | ||||||||||||
| PIK3C2G | KDWCRWYLM | OVARY | 964 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 6 | 0.11 | EFO27 | Y | 8 | 10 | 0 | N | ||||||||||||
| PIK3C2G | KEKTKDWCR | OVARY | 960 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 5 | 0.11 | EFO27 | Y | 3 | 9 | 0 | N | ||||||||||||
| PIK3C2G | KFVGGKQNL | OVARY | 1374 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 5 | 0.11 | IGROV1 | Y | 8 | 11 | 0 | N | ||||||||||||
| PIK3C2G | KHMKNISQM | OVARY | 1348 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 3 | 0.11 | IGROV1 | N | 5 | 0 | 0 | N | ||||||||||||
| PIK3C2G | KNISQMALR | OVARY | 1351 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 5 | 0.11 | IGROV1 | Y | 3 | 13 | 0 | N | ||||||||||||
| PIK3C2G | KQNLFQNVR | OVARY | 1379 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 5 | 0.11 | IGROV1 | Y | 7 | 9 | 0 | N | ||||||||||||
| PIK3C2G | KTKDWCRWY | OVARY | 962 | p.I960fs | c.2879_2879delT | Frame_Shift_Del | 6 | 0.11 | EFO27 | Y | 6 | 14 | 0 | N | ||||||||||||
| PIK3C2G | LCHVLIILS | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 300 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | N | 0 | 0 | 6 | N | ||||||||||||
| PIK3C2G | LFILCHVLI | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 297 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | N | 8 | 0 | 23 | N | ||||||||||||
| PIK3C2G | LFQNVRTPL | OVARY | 1382 | p.T1353fs | c.4059_4062delAGTT | Frame_Shift_Del | 5 | 0.11 | IGROV1 | N | 9 | 0 | 0 | Y | ||||||||||||
| PIK3C2G | LGRSGALLQ | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 265 | p.V264fs | c.791_800delTTAATTTCAA | Frame_Shift_Del | 5 | 0.11 | MOLM13 | N | 0 | 0 | 12 | N | ||||||||||||
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