Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MAP3K4 | ALAVAMLSF | ENDOMETRIUM | 190 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | N | 5 | 0 | 0 | N | ||||||||||||
| MAP3K4 | AMLSFQYLC | ENDOMETRIUM | 194 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | Y | 4 | 9 | 0 | N | ||||||||||||
| MAP3K4 | ATQGLIFYK | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1092 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 4 | 0.11 | MOLP2 | Y | 5 | 11 | 0 | N | ||||||||||||
| MAP3K4 | AVAMLSFQY | ENDOMETRIUM | 192 | p.P175fs | c.525_525delA | Frame_Shift_Del | 6 | 0.11 | MFE296 | N | 6 | 0 | 0 | N | ||||||||||||
| MAP3K4 | DPRVPESDS | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 468 | p.E473fs | c.1418_1418delA | Frame_Shift_Del | 3 | 0.11 | JEKO1 | N | 5 | 0 | 0 | N | ||||||||||||
| MAP3K4 | EYHKEVVWG | STOMACH | 1045 | p.V1050fs | c.3150_3160delTGTTCGTTTGA | Frame_Shift_Del | 2 | 0.11 | SNU601 | N | 0 | 0 | 0 | N | ||||||||||||
| MAP3K4 | FEYHKEVVW | STOMACH | 1044 | p.V1050fs | c.3150_3160delTGTTCGTTTGA | Frame_Shift_Del | 1 | 0.11 | SNU601 | N | 8 | 0 | 0 | N | ||||||||||||
| MAP3K4 | FQLYQKMTS | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1107 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | N | 2 | 0 | 36 | N | ||||||||||||
| MAP3K4 | FQMWISISL | ENDOMETRIUM | 179 | p.P175fs | c.525_525delA | Frame_Shift_Del | 6 | 0.11 | MFE296 | Y | 18 | 10 | 25 | N | ||||||||||||
| MAP3K4 | FYKQLNLPL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1098 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | Y | 9 | 10 | 9 | N | ||||||||||||
| MAP3K4 | GGSLPKNQF | ENDOMETRIUM | 171 | p.P175fs | c.525_525delA | Frame_Shift_Del | 3 | 0.11 | MFE296 | N | 2 | 0 | 0 | Y | ||||||||||||
| MAP3K4 | GLIFYKQLN | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1095 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | N | 1 | 0 | 0 | N | ||||||||||||
| MAP3K4 | GSLPKNQFQ | ENDOMETRIUM | 172 | p.P175fs | c.525_525delA | Frame_Shift_Del | 4 | 0.11 | MFE296 | N | 0 | 0 | 0 | N | ||||||||||||
| MAP3K4 | IFYKQLNLP | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1097 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | N | 0 | 0 | 1 | N | ||||||||||||
| MAP3K4 | ISDPRVPES | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 466 | p.E473fs | c.1418_1418delA | Frame_Shift_Del | 1 | 0.11 | JEKO1 | N | 2 | 0 | 0 | Y | ||||||||||||
| MAP3K4 | ISISLTSAL | ENDOMETRIUM | 183 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | N | 17 | 0 | 8 | N | ||||||||||||
| MAP3K4 | ISLTSALAV | ENDOMETRIUM | 185 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | N | 6 | 0 | 2 | N | ||||||||||||
| MAP3K4 | KNQFQMWIS | ENDOMETRIUM | 176 | p.P175fs | c.525_525delA | Frame_Shift_Del | 6 | 0.11 | MFE296 | N | 0 | 0 | 0 | N | ||||||||||||
| MAP3K4 | KQLNLPLFQ | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1100 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | N | 0 | 0 | 0 | N | ||||||||||||
| MAP3K4 | LAVAMLSFQ | ENDOMETRIUM | 191 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | N | 0 | 0 | 0 | N | ||||||||||||
| MAP3K4 | LFQLYQKMT | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1106 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | N | 1 | 0 | 0 | N | ||||||||||||
| MAP3K4 | LIFYKQLNL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1096 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | N | 15 | 0 | 11 | N | ||||||||||||
| MAP3K4 | LNLPLFQLY | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1102 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | N | 9 | 0 | 0 | N | ||||||||||||
| MAP3K4 | LPKNQFQMW | ENDOMETRIUM | 174 | p.P175fs | c.525_525delA | Frame_Shift_Del | 6 | 0.11 | MFE296 | N | 7 | 0 | 0 | N | ||||||||||||
| MAP3K4 | LPLFQLYQK | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1104 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | N | 6 | 0 | 0 | N | ||||||||||||
| MAP3K4 | LSFQYLCPC | ENDOMETRIUM | 196 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | N | 1 | 0 | 0 | N | ||||||||||||
| MAP3K4 | LTSALAVAM | ENDOMETRIUM | 187 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | N | 4 | 0 | 1 | N | ||||||||||||
| MAP3K4 | MLSFQYLCP | ENDOMETRIUM | 195 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | N | 0 | 0 | 3 | N | ||||||||||||
| MAP3K4 | MWISISLTS | ENDOMETRIUM | 181 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | N | 0 | 0 | 28 | N | ||||||||||||
| MAP3K4 | NLPLFQLYQ | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1103 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | N | 1 | 0 | 0 | N | ||||||||||||
| MAP3K4 | NQFQMWISI | ENDOMETRIUM | 177 | p.P175fs | c.525_525delA | Frame_Shift_Del | 6 | 0.11 | MFE296 | Y | 13 | 12 | 0 | N | ||||||||||||
| MAP3K4 | PKNQFQMWI | ENDOMETRIUM | 175 | p.P175fs | c.525_525delA | Frame_Shift_Del | 6 | 0.11 | MFE296 | N | 5 | 0 | 0 | N | ||||||||||||
| MAP3K4 | PLFQLYQKM | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1105 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | N | 3 | 0 | 0 | N | ||||||||||||
| MAP3K4 | PRVPESDSP | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 469 | p.E473fs | c.1418_1418delA | Frame_Shift_Del | 3 | 0.11 | JEKO1 | N | 0 | 0 | 0 | N | ||||||||||||
| MAP3K4 | PRWATQGLI | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1089 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 2 | 0.11 | MOLP2 | N | 3 | 0 | 0 | N | ||||||||||||
| MAP3K4 | QFQMWISIS | ENDOMETRIUM | 178 | p.P175fs | c.525_525delA | Frame_Shift_Del | 6 | 0.11 | MFE296 | N | 0 | 0 | 0 | N | ||||||||||||
| MAP3K4 | QGLIFYKQL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1094 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | N | 15 | 0 | 0 | N | ||||||||||||
| MAP3K4 | QLNLPLFQL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1101 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | Y | 10 | 11 | 0 | N | ||||||||||||
| MAP3K4 | QMWISISLT | ENDOMETRIUM | 180 | p.P175fs | c.525_525delA | Frame_Shift_Del | 6 | 0.11 | MFE296 | N | 5 | 0 | 0 | N | ||||||||||||
| MAP3K4 | RPRWATQGL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1088 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 1 | 0.11 | MOLP2 | Y | 15 | 11 | 0 | N | ||||||||||||
| MAP3K4 | RWATQGLIF | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1090 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 2 | 0.11 | MOLP2 | N | 3 | 0 | 0 | N | ||||||||||||
| MAP3K4 | SALAVAMLS | ENDOMETRIUM | 189 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | N | 2 | 0 | 0 | N | ||||||||||||
| MAP3K4 | SDPRVPESD | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 467 | p.E473fs | c.1418_1418delA | Frame_Shift_Del | 2 | 0.11 | JEKO1 | N | 0 | 0 | 0 | N | ||||||||||||
| MAP3K4 | SFQYLCPCL | ENDOMETRIUM | 197 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | N | 8 | 0 | 0 | N | ||||||||||||
| MAP3K4 | SISLTSALA | ENDOMETRIUM | 184 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | N | 0 | 0 | 0 | N | ||||||||||||
| MAP3K4 | SLPKNQFQM | ENDOMETRIUM | 173 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | Y | 10 | 9 | 0 | Y | ||||||||||||
| MAP3K4 | SLTSALAVA | ENDOMETRIUM | 186 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | N | 3 | 0 | 0 | N | ||||||||||||
| MAP3K4 | SVGGSLPKN | ENDOMETRIUM | 169 | p.P175fs | c.525_525delA | Frame_Shift_Del | 1 | 0.11 | MFE296 | N | 0 | 0 | 0 | N | ||||||||||||
| MAP3K4 | TQGLIFYKQ | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1093 | p.F1096fs | c.3286_3286delT | Frame_Shift_Del | 5 | 0.11 | MOLP2 | N | 0 | 0 | 0 | N | ||||||||||||
| MAP3K4 | TSALAVAML | ENDOMETRIUM | 188 | p.P175fs | c.525_525delA | Frame_Shift_Del | 5 | 0.11 | MFE296 | Y | 9 | 10 | 0 | N | ||||||||||||
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