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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
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Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
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MAP3K1 | CTRWMIVQR | BREAST | 173 | p.R162fs | c.485_485delG | Frame_Shift_Del | 6 | 0.11 | MDAMB415 | Y | 5 | 10 | 0 | N | ||||||||||||
MAP3K1 | GCTRWMIVQ | BREAST | 172 | p.R162fs | c.485_485delG | Frame_Shift_Del | 6 | 0.11 | MDAMB415 | N | 0 | 0 | 0 | N | ||||||||||||
MAP3K1 | KGCTRWMIV | BREAST | 171 | p.R162fs | c.485_485delG | Frame_Shift_Del | 6 | 0.11 | MDAMB415 | N | 7 | 0 | 0 | N | ||||||||||||
MAP3K1 | LSKGCTRWM | BREAST | 169 | p.R162fs | c.485_485delG | Frame_Shift_Del | 6 | 0.11 | MDAMB415 | N | 3 | 0 | 1 | N | ||||||||||||
MAP3K1 | RWMIVQRNE | BREAST | 175 | p.R162fs | c.485_485delG | Frame_Shift_Del | 6 | 0.11 | MDAMB415 | N | 0 | 0 | 0 | N | ||||||||||||
MAP3K1 | SKGCTRWMI | BREAST | 170 | p.R162fs | c.485_485delG | Frame_Shift_Del | 6 | 0.11 | MDAMB415 | Y | 2 | 13 | 0 | N | ||||||||||||
MAP3K1 | TRWMIVQRN | BREAST | 174 | p.R162fs | c.485_485delG | Frame_Shift_Del | 6 | 0.11 | MDAMB415 | N | 2 | 0 | 0 | N | ||||||||||||
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