Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GPR112 | ALTITTFCV | PANCREAS | 1369 | p.T1374fs | c.4122_4122delT | Frame_Shift_Del | 2 | 0.11 | ASPC1 | Y | 6 | 9 | 0 | N | ||||||||||||
| GPR112 | ANCFKNFLT | ENDOMETRIUM | 2445 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
| GPR112 | ANLSGKSQS | ENDOMETRIUM | 2433 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
| GPR112 | AQTRCIKMR | ENDOMETRIUM | 2410 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 2 | 0.11 | HEC108 | N | 5 | 0 | 0 | N | ||||||||||||
| GPR112 | ARVPFQHIL | PANCREAS | 1382 | p.T1374fs | c.4122_4122delT | Frame_Shift_Del | 5 | 0.11 | ASPC1 | Y | 9 | 9 | 0 | N | ||||||||||||
| GPR112 | ASPEGKVPL | BONE | 707 | p.G713fs | c.2137_2137delG | Frame_Shift_Del | 3 | 0.11 | HOS | N | 13 | 0 | 0 | N | ||||||||||||
| GPR112 | ASTRANLSG | ENDOMETRIUM | 2429 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 4 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
| GPR112 | CFKNFLTRL | ENDOMETRIUM | 2447 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | Y | 5 | 12 | 0 | N | ||||||||||||
| GPR112 | CIKMRMEMP | ENDOMETRIUM | 2414 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 1 | 0 | 0 | N | ||||||||||||
| GPR112 | CVLKRKARV | PANCREAS | 1376 | p.T1374fs | c.4122_4122delT | Frame_Shift_Del | 5 | 0.11 | ASPC1 | Y | 7 | 10 | 0 | N | ||||||||||||
| GPR112 | DSVQSASTR | ENDOMETRIUM | 2424 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 4 | 0.11 | HEC108 | N | 3 | 0 | 0 | N | ||||||||||||
| GPR112 | EGKVPLPMM | BONE | 710 | p.G713fs | c.2137_2137delG | Frame_Shift_Del | 5 | 0.11 | HOS | N | 4 | 0 | 0 | N | ||||||||||||
| GPR112 | EMPQDSVQS | ENDOMETRIUM | 2420 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 2 | 0 | 0 | N | ||||||||||||
| GPR112 | FCVLKRKAR | PANCREAS | 1375 | p.T1374fs | c.4122_4122delT | Frame_Shift_Del | 5 | 0.11 | ASPC1 | N | 5 | 0 | 8 | N | ||||||||||||
| GPR112 | FKNFLTRLW | ENDOMETRIUM | 2448 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 5 | 0 | 16 | N | ||||||||||||
| GPR112 | FLTRLWILL | ENDOMETRIUM | 2451 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | Y | 14 | 13 | 2 | N | ||||||||||||
| GPR112 | FQHILPGLW | PANCREAS | 1386 | p.T1374fs | c.4122_4122delT | Frame_Shift_Del | 5 | 0.11 | ASPC1 | N | 6 | 0 | 5 | N | ||||||||||||
| GPR112 | FQWHTICLY | LARGE_INTESTINE | 117 | p.L124fs | c.372_372delG | Frame_Shift_Del | 1 | 0.11 | CW2 | Y | 11 | 14 | 8 | N | ||||||||||||
| GPR112 | GKSQSLNNA | ENDOMETRIUM | 2437 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 1 | 0 | 0 | N | ||||||||||||
| GPR112 | GKVPLPMML | BONE | 711 | p.G713fs | c.2137_2137delG | Frame_Shift_Del | 5 | 0.11 | HOS | N | 7 | 0 | 0 | N | ||||||||||||
| GPR112 | HTICLYGMV | LARGE_INTESTINE | 120 | p.L124fs | c.372_372delG | Frame_Shift_Del | 4 | 0.11 | CW2 | N | 6 | 0 | 0 | N | ||||||||||||
| GPR112 | IKMRMEMPQ | ENDOMETRIUM | 2415 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 0 | 0 | 15 | N | ||||||||||||
| GPR112 | ITTFCVLKR | PANCREAS | 1372 | p.T1374fs | c.4122_4122delT | Frame_Shift_Del | 5 | 0.11 | ASPC1 | Y | 7 | 9 | 9 | N | ||||||||||||
| GPR112 | KARVPFQHI | PANCREAS | 1381 | p.T1374fs | c.4122_4122delT | Frame_Shift_Del | 6 | 0.11 | ASPC1 | Y | 8 | 10 | 0 | N | ||||||||||||
| GPR112 | KASPEGKVP | BONE | 706 | p.G713fs | c.2137_2137delG | Frame_Shift_Del | 2 | 0.11 | HOS | N | 0 | 0 | 0 | N | ||||||||||||
| GPR112 | KMRMEMPQD | ENDOMETRIUM | 2416 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
| GPR112 | KNFLTRLWI | ENDOMETRIUM | 2449 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 10 | 0 | 0 | N | ||||||||||||
| GPR112 | KRKARVPFQ | PANCREAS | 1379 | p.T1374fs | c.4122_4122delT | Frame_Shift_Del | 6 | 0.11 | ASPC1 | N | 2 | 0 | 0 | N | ||||||||||||
| GPR112 | KSQSLNNAN | ENDOMETRIUM | 2438 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 1 | 0 | 0 | N | ||||||||||||
| GPR112 | KVPLPMMLL | BONE | 712 | p.G713fs | c.2137_2137delG | Frame_Shift_Del | 5 | 0.11 | HOS | Y | 15 | 9 | 0 | N | ||||||||||||
| GPR112 | LKASPEGKV | BONE | 705 | p.G713fs | c.2137_2137delG | Frame_Shift_Del | 1 | 0.11 | HOS | N | 4 | 0 | 0 | N | ||||||||||||
| GPR112 | LKRKARVPF | PANCREAS | 1378 | p.T1374fs | c.4122_4122delT | Frame_Shift_Del | 5 | 0.11 | ASPC1 | N | 3 | 0 | 17 | N | ||||||||||||
| GPR112 | LLQPDIQQL | BONE | 719 | p.G713fs | c.2137_2137delG | Frame_Shift_Del | 4 | 0.11 | HOS | N | 16 | 0 | 0 | N | ||||||||||||
| GPR112 | LNNANCFKN | ENDOMETRIUM | 2442 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
| GPR112 | LPMMLLQPD | BONE | 715 | p.G713fs | c.2137_2137delG | Frame_Shift_Del | 5 | 0.11 | HOS | N | 2 | 0 | 0 | N | ||||||||||||
| GPR112 | LQPDIQQLY | BONE | 720 | p.G713fs | c.2137_2137delG | Frame_Shift_Del | 4 | 0.11 | HOS | N | 10 | 0 | 7 | N | ||||||||||||
| GPR112 | LSGKSQSLN | ENDOMETRIUM | 2435 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
| GPR112 | LTITTFCVL | PANCREAS | 1370 | p.T1374fs | c.4122_4122delT | Frame_Shift_Del | 3 | 0.11 | ASPC1 | N | 16 | 0 | 2 | N | ||||||||||||
| GPR112 | LTRLWILLI | ENDOMETRIUM | 2452 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 9 | 0 | 18 | N | ||||||||||||
| GPR112 | MEMPQDSVQ | ENDOMETRIUM | 2419 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 2 | 0 | 0 | N | ||||||||||||
| GPR112 | MLLQPDIQQ | BONE | 718 | p.G713fs | c.2137_2137delG | Frame_Shift_Del | 5 | 0.11 | HOS | N | 0 | 0 | 0 | N | ||||||||||||
| GPR112 | MMLLQPDIQ | BONE | 717 | p.G713fs | c.2137_2137delG | Frame_Shift_Del | 6 | 0.11 | HOS | N | 0 | 0 | 17 | N | ||||||||||||
| GPR112 | MPQDSVQSA | ENDOMETRIUM | 2421 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 9 | 0 | 6 | N | ||||||||||||
| GPR112 | MRMEMPQDS | ENDOMETRIUM | 2417 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 2 | 0 | 40 | N | ||||||||||||
| GPR112 | NANCFKNFL | ENDOMETRIUM | 2444 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | Y | 15 | 10 | 0 | N | ||||||||||||
| GPR112 | NCFKNFLTR | ENDOMETRIUM | 2446 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 7 | 0 | 0 | N | ||||||||||||
| GPR112 | NFLTRLWIL | ENDOMETRIUM | 2450 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | Y | 9 | 9 | 0 | N | ||||||||||||
| GPR112 | NLSGKSQSL | ENDOMETRIUM | 2434 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 12 | 0 | 0 | N | ||||||||||||
| GPR112 | NNANCFKNF | ENDOMETRIUM | 2443 | p.I2415fs | c.7245_7245delA | Frame_Shift_Del | 6 | 0.11 | HEC108 | Y | 2 | 12 | 0 | N | ||||||||||||
| GPR112 | PDIQQLYPN | BONE | 722 | p.G713fs | c.2137_2137delG | Frame_Shift_Del | 5 | 0.11 | HOS | N | 0 | 0 | 0 | N | ||||||||||||
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