Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FMN2 | AAGAGWTKD | LARGE_INTESTINE | 166 | p.G168fs | c.502_503delGG | Frame_Shift_Del | 5 | 0.11 | CL40 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | AGAGWTKDQ | LARGE_INTESTINE | 167 | p.G168fs | c.502_503delGG | Frame_Shift_Del | 5 | 0.11 | CL40 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | AGWTKDQLG | LARGE_INTESTINE | 169 | p.G168fs | c.502_503delGG | Frame_Shift_Del | 5 | 0.11 | CL40 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | AKVDLRQSS | ENDOMETRIUM | 773 | p.C773fs | c.2319_2319delC | Frame_Shift_Del | 5 | 0.11 | HEC59 | N | 1 | 0 | 0 | N | ||||||||||||
| FMN2 | APGSRGGRN | ENDOMETRIUM | 440 | p.P410fs | c.1228_1228delC | Frame_Shift_Del | 5 | 0.11 | AN3CA | N | 3 | 0 | 0 | N | ||||||||||||
| FMN2 | ARPITPRLS | ENDOMETRIUM | 427 | p.P410fs | c.1228_1228delC | Frame_Shift_Del | 5 | 0.11 | AN3CA | N | 2 | 0 | 0 | N | ||||||||||||
| FMN2 | ATSRPPPGS | ENDOMETRIUM | 417 | p.P410fs | c.1228_1228delC | Frame_Shift_Del | 4 | 0.11 | AN3CA | N | 0 | 0 | 0 | Y | ||||||||||||
| FMN2 | AYLLRRLYP | LUNG | 919 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | AYPFLPLFP | LUNG | 963 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | AYSLCPLYP | LUNG | 930 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | CFKPTRSSP | ENDOMETRIUM | 407 | p.P410fs | c.1228_1228delC | Frame_Shift_Del | 5 | 0.11 | AN3CA | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | CPLYPEREY | LUNG | 934 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 10 | 0 | 0 | N | ||||||||||||
| FMN2 | CPPGAKVDL | ENDOMETRIUM | 769 | p.C773fs | c.2319_2319delC | Frame_Shift_Del | 4 | 0.11 | HEC59 | N | 17 | 0 | 0 | N | ||||||||||||
| FMN2 | DLRQSSVQR | ENDOMETRIUM | 776 | p.C773fs | c.2319_2319delC | Frame_Shift_Del | 5 | 0.11 | HEC59 | N | 5 | 0 | 0 | N | ||||||||||||
| FMN2 | DQLGLGHGH | LARGE_INTESTINE | 174 | p.G168fs | c.502_503delGG | Frame_Shift_Del | 5 | 0.11 | CL40 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | DVETAAGAG | LARGE_INTESTINE | 162 | p.G168fs | c.502_503delGG | Frame_Shift_Del | 1 | 0.11 | CL40 | N | 1 | 0 | 0 | N | ||||||||||||
| FMN2 | EMLPPPPLL | LUNG | 906 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 2 | 0.11 | RERFLCAD2 | Y | 14 | 9 | 0 | N | ||||||||||||
| FMN2 | EQAYSLCPL | LUNG | 928 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 7 | 0 | 0 | N | ||||||||||||
| FMN2 | EQEYLLHPL | LUNG | 972 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 4 | 0.11 | RERFLCAD2 | N | 8 | 0 | 0 | N | ||||||||||||
| FMN2 | ERAYLLRRL | LUNG | 917 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | Y | 7 | 12 | 0 | N | ||||||||||||
| FMN2 | EREYLLRPL | LUNG | 939 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | Y | 7 | 12 | 0 | N | ||||||||||||
| FMN2 | ERQYPLRPL | LUNG | 950 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 4 | 0.11 | RERFLCAD2 | Y | 7 | 9 | 0 | N | ||||||||||||
| FMN2 | ETAAGAGWT | LARGE_INTESTINE | 164 | p.G168fs | c.502_503delGG | Frame_Shift_Del | 3 | 0.11 | CL40 | N | 1 | 0 | 0 | N | ||||||||||||
| FMN2 | EYLLHPLYP | LUNG | 974 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | EYLLRPLYP | LUNG | 941 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | FKPTRSSPP | ENDOMETRIUM | 408 | p.P410fs | c.1228_1228delC | Frame_Shift_Del | 5 | 0.11 | AN3CA | N | 2 | 0 | 3 | N | ||||||||||||
| FMN2 | FLPLFPEQE | LUNG | 966 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 3 | 0 | 2 | N | ||||||||||||
| FMN2 | FPEQEYLLH | LUNG | 970 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 4 | 0.11 | RERFLCAD2 | N | 4 | 0 | 0 | N | ||||||||||||
| FMN2 | FPERAYLLR | LUNG | 915 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 6 | 0.11 | RERFLCAD2 | N | 8 | 0 | 0 | N | ||||||||||||
| FMN2 | FPGQAYPFL | LUNG | 959 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 22 | 0 | 0 | Y | ||||||||||||
| FMN2 | GAGWTKDQL | LARGE_INTESTINE | 168 | p.G168fs | c.502_503delGG | Frame_Shift_Del | 5 | 0.11 | CL40 | Y | 9 | 10 | 0 | N | ||||||||||||
| FMN2 | GAKVDLRQS | ENDOMETRIUM | 772 | p.C773fs | c.2319_2319delC | Frame_Shift_Del | 5 | 0.11 | HEC59 | N | 1 | 0 | 0 | N | ||||||||||||
| FMN2 | GQAYPFLPL | LUNG | 961 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | Y | 15 | 10 | 0 | Y | ||||||||||||
| FMN2 | GSRGGRNPP | ENDOMETRIUM | 442 | p.P410fs | c.1228_1228delC | Frame_Shift_Del | 5 | 0.11 | AN3CA | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | GSSARPITP | ENDOMETRIUM | 424 | p.P410fs | c.1228_1228delC | Frame_Shift_Del | 4 | 0.11 | AN3CA | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | GWTKDQLGL | LARGE_INTESTINE | 170 | p.G168fs | c.502_503delGG | Frame_Shift_Del | 5 | 0.11 | CL40 | N | 4 | 0 | 0 | N | ||||||||||||
| FMN2 | IPPPPPLPE | ENDOMETRIUM | 975 | p.P983fs | c.2947_2947delC | Frame_Shift_Del | 1 | 0.11 | HEC108 | N | 1 | 0 | 0 | N | ||||||||||||
| FMN2 | IRAPGSRGG | ENDOMETRIUM | 438 | p.P410fs | c.1228_1228delC | Frame_Shift_Del | 5 | 0.11 | AN3CA | N | 0 | 0 | 1 | N | ||||||||||||
| FMN2 | ITPRLSPLI | ENDOMETRIUM | 430 | p.P410fs | c.1228_1228delC | Frame_Shift_Del | 5 | 0.11 | AN3CA | N | 6 | 0 | 0 | N | ||||||||||||
| FMN2 | KDQLGLGHG | LARGE_INTESTINE | 173 | p.G168fs | c.502_503delGG | Frame_Shift_Del | 5 | 0.11 | CL40 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | KPTRSSPPA | ENDOMETRIUM | 409 | p.P410fs | c.1228_1228delC | Frame_Shift_Del | 5 | 0.11 | AN3CA | N | 8 | 0 | 0 | N | ||||||||||||
| FMN2 | KVDLRQSSV | ENDOMETRIUM | 774 | p.C773fs | c.2319_2319delC | Frame_Shift_Del | 5 | 0.11 | HEC59 | Y | 5 | 9 | 0 | N | ||||||||||||
| FMN2 | LCPLYPERE | LUNG | 933 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | LFPEQEYLL | LUNG | 969 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 4 | 0.11 | RERFLCAD2 | N | 10 | 0 | 0 | N | ||||||||||||
| FMN2 | LFPGQAYPF | LUNG | 958 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 7 | 0 | 0 | Y | ||||||||||||
| FMN2 | LIRAPGSRG | ENDOMETRIUM | 437 | p.P410fs | c.1228_1228delC | Frame_Shift_Del | 5 | 0.11 | AN3CA | N | 0 | 0 | 0 | N | ||||||||||||
| FMN2 | LLFPERAYL | LUNG | 913 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | Y | 15 | 13 | 0 | N | ||||||||||||
| FMN2 | LLRRLYPEQ | LUNG | 921 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 0 | 0 | 3 | Y | ||||||||||||
| FMN2 | LPERAYPLL | ENDOMETRIUM | 981 | p.P983fs | c.2947_2947delC | Frame_Shift_Del | 4 | 0.11 | HEC108 | N | 19 | 0 | 0 | N | ||||||||||||
| FMN2 | LPLFPEQEY | LUNG | 967 | p.P913fs | c.2737_2737delC | Frame_Shift_Del | 5 | 0.11 | RERFLCAD2 | N | 10 | 0 | 0 | N | ||||||||||||
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