Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHD1 | AGFEKTKNQ | LARGE_INTESTINE | 305 | p.N310fs | c.929_929delA | Frame_Shift_Del | 3 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
| CHD1 | AKKKLFLVR | PROSTATE | 1318 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 4 | 0.11 | 22RV1 | N | 1 | 0 | 0 | N | ||||||||||||
| CHD1 | DLAKKKLFL | PROSTATE | 1316 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 4 | 0.11 | 22RV1 | Y | 6 | 9 | 0 | N | ||||||||||||
| CHD1 | DPNAGFEKT | LARGE_INTESTINE | 302 | p.N310fs | c.929_929delA | Frame_Shift_Del | 1 | 0.11 | SNUC4 | N | 4 | 0 | 0 | N | ||||||||||||
| CHD1 | EKQELRRIK | PROSTATE | 1332 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 4 | 0.11 | 22RV1 | N | 1 | 0 | 0 | N | ||||||||||||
| CHD1 | EKTKNQERF | LARGE_INTESTINE | 308 | p.N310fs | c.929_929delA | Frame_Shift_Del | 5 | 0.11 | SNUC4 | N | 2 | 0 | 0 | N | ||||||||||||
| CHD1 | EVQRGEKQE | PROSTATE | 1327 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 0 | 0 | 0 | N | ||||||||||||
| CHD1 | FEKTKNQER | LARGE_INTESTINE | 307 | p.N310fs | c.929_929delA | Frame_Shift_Del | 5 | 0.11 | SNUC4 | N | 2 | 0 | 3 | N | ||||||||||||
| CHD1 | FLVREVQRG | PROSTATE | 1323 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 1 | 0 | 11 | N | ||||||||||||
| CHD1 | GEKQELRRI | PROSTATE | 1331 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 6 | 0 | 0 | N | ||||||||||||
| CHD1 | GFEKTKNQE | LARGE_INTESTINE | 306 | p.N310fs | c.929_929delA | Frame_Shift_Del | 4 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
| CHD1 | KKKLFLVRE | PROSTATE | 1319 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 0 | 0 | 0 | N | ||||||||||||
| CHD1 | KKLFLVREV | PROSTATE | 1320 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 4 | 0 | 0 | N | ||||||||||||
| CHD1 | KLFLVREVQ | PROSTATE | 1321 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 1 | 0 | 0 | N | ||||||||||||
| CHD1 | KQELRRIKQ | PROSTATE | 1333 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 1 | 0 | 0 | N | ||||||||||||
| CHD1 | KTKNQERFS | LARGE_INTESTINE | 309 | p.N310fs | c.929_929delA | Frame_Shift_Del | 5 | 0.11 | SNUC4 | N | 1 | 0 | 0 | N | ||||||||||||
| CHD1 | LAKKKLFLV | PROSTATE | 1317 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 4 | 0.11 | 22RV1 | N | 8 | 0 | 0 | N | ||||||||||||
| CHD1 | LFLVREVQR | PROSTATE | 1322 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 2 | 0 | 0 | N | ||||||||||||
| CHD1 | LSRDLAKKK | PROSTATE | 1313 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 1 | 0.11 | 22RV1 | N | 1 | 0 | 4 | N | ||||||||||||
| CHD1 | LVREVQRGE | PROSTATE | 1324 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 0 | 0 | 1 | N | ||||||||||||
| CHD1 | NAGFEKTKN | LARGE_INTESTINE | 304 | p.N310fs | c.929_929delA | Frame_Shift_Del | 2 | 0.11 | SNUC4 | N | 1 | 0 | 0 | N | ||||||||||||
| CHD1 | PNAGFEKTK | LARGE_INTESTINE | 303 | p.N310fs | c.929_929delA | Frame_Shift_Del | 1 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
| CHD1 | QRGEKQELR | PROSTATE | 1329 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 3 | 0 | 0 | N | ||||||||||||
| CHD1 | RDLAKKKLF | PROSTATE | 1315 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 3 | 0.11 | 22RV1 | N | 5 | 0 | 0 | N | ||||||||||||
| CHD1 | REVQRGEKQ | PROSTATE | 1326 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 1 | 0 | 0 | N | ||||||||||||
| CHD1 | RGEKQELRR | PROSTATE | 1330 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 1 | 0 | 0 | N | ||||||||||||
| CHD1 | SRDLAKKKL | PROSTATE | 1314 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 2 | 0.11 | 22RV1 | Y | 5 | 10 | 0 | N | ||||||||||||
| CHD1 | TKNQERFSI | LARGE_INTESTINE | 310 | p.N310fs | c.929_929delA | Frame_Shift_Del | 5 | 0.11 | SNUC4 | N | 2 | 0 | 0 | N | ||||||||||||
| CHD1 | VQRGEKQEL | PROSTATE | 1328 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 5 | 0.11 | 22RV1 | N | 8 | 0 | 7 | N | ||||||||||||
| CHD1 | VREVQRGEK | PROSTATE | 1325 | p.K1320fs | c.3960_3960delA | Frame_Shift_Del | 6 | 0.11 | 22RV1 | N | 3 | 0 | 3 | N | ||||||||||||
| CHD1 | AKQLLMLAI | OVARY | 234 | p.K210fs | c.629_629delA | Frame_Shift_Del | 4 | 0.22 | IGROV1 | N | 1 | 0 | 0 | N | ||||||||||||
| CHD1 | AKQLLMLAI | LARGE_INTESTINE | 234 | p.K210fs | c.629_629delA | Frame_Shift_Del | 4 | 0.22 | LS180 | N | 1 | 0 | 0 | N | ||||||||||||
| CHD1 | DRLIHLRRM | OVARY | 211 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | IGROV1 | Y | 5 | 9 | 0 | N | ||||||||||||
| CHD1 | DRLIHLRRM | LARGE_INTESTINE | 211 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | LS180 | Y | 5 | 9 | 0 | N | ||||||||||||
| CHD1 | EVLVAKQLL | OVARY | 230 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | IGROV1 | N | 11 | 0 | 0 | N | ||||||||||||
| CHD1 | EVLVAKQLL | LARGE_INTESTINE | 230 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | LS180 | N | 11 | 0 | 0 | N | ||||||||||||
| CHD1 | GKKILGQKR | OVARY | 202 | p.K210fs | c.629_629delA | Frame_Shift_Del | 1 | 0.22 | IGROV1 | N | 1 | 0 | 0 | N | ||||||||||||
| CHD1 | GKKILGQKR | LARGE_INTESTINE | 202 | p.K210fs | c.629_629delA | Frame_Shift_Del | 1 | 0.22 | LS180 | N | 1 | 0 | 0 | N | ||||||||||||
| CHD1 | GQKRDRLIH | OVARY | 207 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | IGROV1 | N | 1 | 0 | 0 | Y | ||||||||||||
| CHD1 | GQKRDRLIH | LARGE_INTESTINE | 207 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | LS180 | N | 1 | 0 | 0 | Y | ||||||||||||
| CHD1 | HLRRMMMKK | OVARY | 215 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | IGROV1 | Y | 5 | 15 | 0 | N | ||||||||||||
| CHD1 | HLRRMMMKK | LARGE_INTESTINE | 215 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | LS180 | Y | 5 | 15 | 0 | N | ||||||||||||
| CHD1 | IHLRRMMMK | OVARY | 214 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | IGROV1 | Y | 0 | 11 | 4 | N | ||||||||||||
| CHD1 | IHLRRMMMK | LARGE_INTESTINE | 214 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | LS180 | Y | 0 | 11 | 4 | N | ||||||||||||
| CHD1 | IKEVLVAKQ | OVARY | 228 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | IGROV1 | N | 0 | 0 | 9 | N | ||||||||||||
| CHD1 | IKEVLVAKQ | LARGE_INTESTINE | 228 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | LS180 | N | 0 | 0 | 9 | N | ||||||||||||
| CHD1 | ILGQKRDRL | OVARY | 205 | p.K210fs | c.629_629delA | Frame_Shift_Del | 4 | 0.22 | IGROV1 | N | 12 | 0 | 0 | Y | ||||||||||||
| CHD1 | ILGQKRDRL | LARGE_INTESTINE | 205 | p.K210fs | c.629_629delA | Frame_Shift_Del | 4 | 0.22 | LS180 | N | 12 | 0 | 0 | Y | ||||||||||||
| CHD1 | IMIKEVLVA | OVARY | 226 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | IGROV1 | N | 6 | 0 | 39 | N | ||||||||||||
| CHD1 | IMIKEVLVA | LARGE_INTESTINE | 226 | p.K210fs | c.629_629delA | Frame_Shift_Del | 5 | 0.22 | LS180 | N | 6 | 0 | 39 | N | ||||||||||||
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