Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
BRAFATTVKSRWSHAEMATOPOIETIC_AND_LYMPHOID_TISSUE598p.599_599T>TTc.1796_1797insTACIn_Frame_Ins20.11SUDHL8N000Y
BRAFDFGLATTVKHAEMATOPOIETIC_AND_LYMPHOID_TISSUE594p.599_599T>TTc.1796_1797insTACIn_Frame_Ins30.11SUDHL8N000N
BRAFFGLATTVKSHAEMATOPOIETIC_AND_LYMPHOID_TISSUE595p.599_599T>TTc.1796_1797insTACIn_Frame_Ins40.11SUDHL8N4033N
BRAFGDFGLATTVHAEMATOPOIETIC_AND_LYMPHOID_TISSUE593p.599_599T>TTc.1796_1797insTACIn_Frame_Ins20.11SUDHL8N700N
BRAFGLATTVKSRHAEMATOPOIETIC_AND_LYMPHOID_TISSUE596p.599_599T>TTc.1796_1797insTACIn_Frame_Ins40.11SUDHL8Y5120Y
BRAFIGDFGLATTHAEMATOPOIETIC_AND_LYMPHOID_TISSUE592p.599_599T>TTc.1796_1797insTACIn_Frame_Ins10.11SUDHL8N100N
BRAFLATTVKSRWHAEMATOPOIETIC_AND_LYMPHOID_TISSUE597p.599_599T>TTc.1796_1797insTACIn_Frame_Ins30.11SUDHL8N300Y
BRAFTTVKSRWSGHAEMATOPOIETIC_AND_LYMPHOID_TISSUE599p.599_599T>TTc.1796_1797insTACIn_Frame_Ins10.11SUDHL8N000Y