Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ATM | AQQRDCYQG | ENDOMETRIUM | 1309 | p.R1312fs | c.3934_3935delAG | Frame_Shift_Del | 5 | 0.11 | ISHIKAWAHERAKLIO02ER | N | 0 | 0 | 0 | N | ||||||||||||
| ATM | EDPFHSWRK | STOMACH | 1585 | p.Q1579fs | c.4736_4736delA | Frame_Shift_Del | 5 | 0.11 | SNU520 | N | 0 | 0 | 0 | N | ||||||||||||
| ATM | KSNTVEDPF | STOMACH | 1580 | p.Q1579fs | c.4736_4736delA | Frame_Shift_Del | 6 | 0.11 | SNU520 | N | 7 | 0 | 0 | N | ||||||||||||
| ATM | NTVEDPFHS | STOMACH | 1582 | p.Q1579fs | c.4736_4736delA | Frame_Shift_Del | 6 | 0.11 | SNU520 | N | 0 | 0 | 0 | N | ||||||||||||
| ATM | PFHSWRKLT | STOMACH | 1587 | p.Q1579fs | c.4736_4736delA | Frame_Shift_Del | 5 | 0.11 | SNU520 | N | 0 | 0 | 0 | N | ||||||||||||
| ATM | QKSNTVEDP | STOMACH | 1579 | p.Q1579fs | c.4736_4736delA | Frame_Shift_Del | 5 | 0.11 | SNU520 | N | 0 | 0 | 0 | N | ||||||||||||
| ATM | QQKSNTVED | STOMACH | 1578 | p.Q1579fs | c.4736_4736delA | Frame_Shift_Del | 5 | 0.11 | SNU520 | N | 1 | 0 | 0 | N | ||||||||||||
| ATM | QQRDCYQGL | ENDOMETRIUM | 1310 | p.R1312fs | c.3934_3935delAG | Frame_Shift_Del | 5 | 0.11 | ISHIKAWAHERAKLIO02ER | N | 9 | 0 | 0 | N | ||||||||||||
| ATM | SNTVEDPFH | STOMACH | 1581 | p.Q1579fs | c.4736_4736delA | Frame_Shift_Del | 6 | 0.11 | SNU520 | N | 0 | 0 | 0 | N | ||||||||||||
| ATM | TQQKSNTVE | STOMACH | 1577 | p.Q1579fs | c.4736_4736delA | Frame_Shift_Del | 5 | 0.11 | SNU520 | N | 0 | 0 | 0 | N | ||||||||||||
| ATM | TVEDPFHSW | STOMACH | 1583 | p.Q1579fs | c.4736_4736delA | Frame_Shift_Del | 6 | 0.11 | SNU520 | N | 2 | 0 | 0 | N | ||||||||||||
| ATM | VEDPFHSWR | STOMACH | 1584 | p.Q1579fs | c.4736_4736delA | Frame_Shift_Del | 5 | 0.11 | SNU520 | N | 1 | 0 | 0 | N | ||||||||||||
| ATM | FTDVDSCGF | STOMACH | 1154 | p.V1153fs | c.3457_3458insT | Frame_Shift_Ins | 5 | 0.11 | SNU1 | N | 6 | 0 | 0 | N | ||||||||||||
| ATM | KSVFTDVDS | STOMACH | 1151 | p.V1153fs | c.3457_3458insT | Frame_Shift_Ins | 5 | 0.11 | SNU1 | N | 1 | 0 | 0 | N | ||||||||||||
| ATM | MNFFPKRAR | LARGE_INTESTINE | 624 | p.N625fs | c.1874_1875insT | Frame_Shift_Ins | 5 | 0.11 | CW2 | N | 2 | 0 | 17 | N | ||||||||||||
| ATM | NFFPKRARM | LARGE_INTESTINE | 625 | p.N625fs | c.1874_1875insT | Frame_Shift_Ins | 5 | 0.11 | CW2 | Y | 2 | 9 | 0 | N | ||||||||||||
| ATM | RKSVFTDVD | STOMACH | 1150 | p.V1153fs | c.3457_3458insT | Frame_Shift_Ins | 5 | 0.11 | SNU1 | N | 0 | 0 | 0 | N | ||||||||||||
| ATM | SVFTDVDSC | STOMACH | 1152 | p.V1153fs | c.3457_3458insT | Frame_Shift_Ins | 5 | 0.11 | SNU1 | N | 1 | 0 | 0 | N | ||||||||||||
| ATM | TDVDSCGFI | STOMACH | 1155 | p.V1153fs | c.3457_3458insT | Frame_Shift_Ins | 5 | 0.11 | SNU1 | N | 5 | 0 | 0 | N | ||||||||||||
| ATM | VFTDVDSCG | STOMACH | 1153 | p.V1153fs | c.3457_3458insT | Frame_Shift_Ins | 5 | 0.11 | SNU1 | N | 0 | 0 | 0 | N | ||||||||||||
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