Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1 | GTVTPPPGW | OVARY | 797 | p.P802fs | c.2404_2404delC | Frame_Shift_Del | 2 | 0.11 | IGROV1 | N | 2 | 0 | 0 | Y | ||||||||||||
| ABL1 | RGTVTPPPG | OVARY | 796 | p.P802fs | c.2404_2404delC | Frame_Shift_Del | 1 | 0.11 | IGROV1 | N | 0 | 0 | 0 | Y | ||||||||||||
| ABL1 | AARNCLIGE | UPPER_AERODIGESTIVE_TRACT | 384 | p.V390I | c.1168G>A | Missense_Mutation | 1 | 0.11 | HSC3 | N | 0 | 0 | 0 | Y | ||||||||||||
| ABL1 | AATLDFSKL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1128 | p.Q1131L | c.3392A>T | Missense_Mutation | 1 | 0.11 | L540 | N | 10 | 0 | 0 | N | ||||||||||||
| ABL1 | ADKNLYTFC | PANCREAS | 1078 | p.G1079D | c.3236G>A | Missense_Mutation | 1 | 0.11 | CAPAN2 | N | 2 | 0 | 0 | N | ||||||||||||
| ABL1 | ADPAKSPKL | STOMACH | 673 | p.P681L | c.2042C>T | Missense_Mutation | 1 | 0.11 | IM95 | N | 6 | 0 | 0 | Y | ||||||||||||
| ABL1 | AGSGPAATL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1123 | p.Q1131L | c.3392A>T | Missense_Mutation | 1 | 0.11 | L540 | Y | 10 | 9 | 0 | N | ||||||||||||
| ABL1 | AGVSNGALR | URINARY_TRACT | 685 | p.P688S | c.2062C>T | Missense_Mutation | 1 | 0.11 | JMSU1 | N | 2 | 0 | 0 | N | ||||||||||||
| ABL1 | AIGEEEGGG | SKIN | 718 | p.T719I | c.2156_2157CC>TT | Missense_Mutation | 1 | 0.11 | COLO792 | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | AISRSSEQM | ENDOMETRIUM | 1061 | p.N1065S | c.3194A>G | Missense_Mutation | 1 | 0.11 | HEC265 | N | 2 | 0 | 0 | N | ||||||||||||
| ABL1 | AKSPKLSNG | STOMACH | 676 | p.P681L | c.2042C>T | Missense_Mutation | 1 | 0.11 | IM95 | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | ALCLAISRS | ENDOMETRIUM | 1057 | p.N1065S | c.3194A>G | Missense_Mutation | 1 | 0.11 | HEC265 | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | AMSPLLPRK | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 586 | p.V587M | c.1759G>A | Missense_Mutation | 1 | 0.11 | CA46 | N | 6 | 0 | 0 | N | ||||||||||||
| ABL1 | ANGAITKGV | ENDOMETRIUM | 1042 | p.S1043N | c.3128G>A | Missense_Mutation | 1 | 0.11 | HEC265 | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | APKSLAYNK | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 426 | p.E428K | c.1282G>A | Missense_Mutation | 1 | 0.11 | TF1 | Y | 2 | 16 | 0 | N | ||||||||||||
| ABL1 | ARNCLIGEN | UPPER_AERODIGESTIVE_TRACT | 385 | p.V390I | c.1168G>A | Missense_Mutation | 1 | 0.11 | HSC3 | N | 2 | 0 | 0 | N | ||||||||||||
| ABL1 | ATLDFSKLL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1129 | p.Q1131L | c.3392A>T | Missense_Mutation | 1 | 0.11 | L540 | N | 21 | 0 | 0 | N | ||||||||||||
| ABL1 | ATYGMSPYL | UPPER_AERODIGESTIVE_TRACT | 452 | p.P460L | c.1379C>T | Missense_Mutation | 1 | 0.11 | CAL27 | N | 17 | 0 | 0 | N | ||||||||||||
| ABL1 | AVLEADKNL | PANCREAS | 1074 | p.G1079D | c.3236G>A | Missense_Mutation | 1 | 0.11 | CAPAN2 | N | 14 | 0 | 0 | N | ||||||||||||
| ABL1 | AVNSDVAKP | LARGE_INTESTINE | 959 | p.A964V | c.2891C>T | Missense_Mutation | 1 | 0.11 | GP2D | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | AVSSLLPRK | LARGE_INTESTINE | 586 | p.P589S | c.1765C>T | Missense_Mutation | 1 | 0.11 | SNU1040 | Y | 4 | 11 | 0 | N | ||||||||||||
| ABL1 | CLAISRSSE | ENDOMETRIUM | 1059 | p.N1065S | c.3194A>G | Missense_Mutation | 1 | 0.11 | HEC265 | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | CLIGENHLV | UPPER_AERODIGESTIVE_TRACT | 388 | p.V390I | c.1168G>A | Missense_Mutation | 1 | 0.11 | HSC3 | N | 6 | 0 | 0 | N | ||||||||||||
| ABL1 | CNWQEVNAV | LUNG | 349 | p.R351W | c.1051C>T | Missense_Mutation | 1 | 0.11 | NCIH1915 | Y | 6 | 14 | 0 | N | ||||||||||||
| ABL1 | DAVNSDVAK | LARGE_INTESTINE | 958 | p.A964V | c.2891C>T | Missense_Mutation | 1 | 0.11 | GP2D | N | 1 | 0 | 0 | N | ||||||||||||
| ABL1 | DGLITTLHH | URINARY_TRACT | 226 | p.Y234H | c.700T>C | Missense_Mutation | 1 | 0.11 | 639V | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | DHEPAMSPL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 582 | p.V587M | c.1759G>A | Missense_Mutation | 1 | 0.11 | CA46 | N | 4 | 0 | 0 | N | ||||||||||||
| ABL1 | DHEPAVSSL | LARGE_INTESTINE | 582 | p.P589S | c.1765C>T | Missense_Mutation | 1 | 0.11 | SNU1040 | N | 4 | 0 | 0 | N | ||||||||||||
| ABL1 | DKKTSLFSA | ENDOMETRIUM | 613 | p.N617S | c.1850A>G | Missense_Mutation | 1 | 0.11 | HEC108 | N | 1 | 0 | 0 | N | ||||||||||||
| ABL1 | DKNLYTFCV | PANCREAS | 1079 | p.G1079D | c.3236G>A | Missense_Mutation | 1 | 0.11 | CAPAN2 | N | 3 | 0 | 0 | Y | ||||||||||||
| ABL1 | DLAARNCLI | UPPER_AERODIGESTIVE_TRACT | 382 | p.V390I | c.1168G>A | Missense_Mutation | 1 | 0.11 | HSC3 | N | 8 | 0 | 0 | N | ||||||||||||
| ABL1 | DPAKSPKLS | STOMACH | 674 | p.P681L | c.2042C>T | Missense_Mutation | 1 | 0.11 | IM95 | N | 3 | 0 | 0 | N | ||||||||||||
| ABL1 | DPLDHEPAM | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 579 | p.V587M | c.1759G>A | Missense_Mutation | 1 | 0.11 | CA46 | Y | 13 | 9 | 0 | N | ||||||||||||
| ABL1 | DQKRPSLPA | BREAST | 11 | p.R13K | c.38G>A | Missense_Mutation | 1 | 0.11 | HCC2157 | N | 2 | 0 | 0 | N | ||||||||||||
| ABL1 | DVAKPSQPG | LARGE_INTESTINE | 963 | p.A964V | c.2891C>T | Missense_Mutation | 1 | 0.11 | GP2D | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | DYLRECNWQ | LUNG | 344 | p.R351W | c.1051C>T | Missense_Mutation | 1 | 0.11 | NCIH1915 | N | 1 | 0 | 0 | N | ||||||||||||
| ABL1 | DYRMEHPEG | BONE | 474 | p.R479H | c.1436G>A | Missense_Mutation | 1 | 0.11 | HS821T | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | EADKNLYTF | PANCREAS | 1077 | p.G1079D | c.3236G>A | Missense_Mutation | 1 | 0.11 | CAPAN2 | N | 4 | 0 | 0 | N | ||||||||||||
| ABL1 | ECNWQEVNA | LUNG | 348 | p.R351W | c.1051C>T | Missense_Mutation | 1 | 0.11 | NCIH1915 | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | EELRVLGYN | OESOPHAGUS | 105 | p.K106E | c.316A>G | Missense_Mutation | 1 | 0.11 | KYSE410 | N | 5 | 0 | 0 | N | ||||||||||||
| ABL1 | EFMTYLNLL | LUNG | 335 | p.G340L | c.1018_1019GG>TT | Missense_Mutation | 1 | 0.11 | NCIH2110 | N | 9 | 0 | 0 | N | ||||||||||||
| ABL1 | EHPEGCPEK | BONE | 478 | p.R479H | c.1436G>A | Missense_Mutation | 1 | 0.11 | HS821T | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | EKDYRMEHP | BONE | 472 | p.R479H | c.1436G>A | Missense_Mutation | 1 | 0.11 | HS821T | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | ELRVLGYNH | OESOPHAGUS | 106 | p.K106E | c.316A>G | Missense_Mutation | 1 | 0.11 | KYSE410 | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | EPAMSPLLP | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 584 | p.V587M | c.1759G>A | Missense_Mutation | 1 | 0.11 | CA46 | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | EPAVSSLLP | LARGE_INTESTINE | 584 | p.P589S | c.1765C>T | Missense_Mutation | 1 | 0.11 | SNU1040 | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | ERIANGAIT | ENDOMETRIUM | 1039 | p.S1043N | c.3128G>A | Missense_Mutation | 1 | 0.11 | HEC265 | N | 3 | 0 | 0 | N | ||||||||||||
| ABL1 | EWGEAQTKN | BREAST | 117 | p.C119G | c.355T>G | Missense_Mutation | 1 | 0.11 | MDAMB436 | N | 0 | 0 | 0 | N | ||||||||||||
| ABL1 | FMTYLNLLD | LUNG | 336 | p.G340L | c.1018_1019GG>TT | Missense_Mutation | 1 | 0.11 | NCIH2110 | N | 3 | 0 | 8 | N | ||||||||||||
| ABL1 | FPIKWTAPK | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 420 | p.E428K | c.1282G>A | Missense_Mutation | 1 | 0.11 | TF1 | N | 7 | 0 | 10 | N | ||||||||||||
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