Browse result page of B3Pdb

The total number entries retrieved from this search are 335, scroll left/right for detailed information.

B3pdbID	PEPTIDE NAME	PEPTIDE SEQUENCE (1-letter)	PEPTIDE SEQUENCE (3-letter)	N-TERMINAL MODIFICATION	C-TERMINAL MODIFICATION	CHEMICAL MODIFICATION	PEPTIDE LENGTH	PEPTIDE CONFORMATION	PEPTIDE NATURE	SOURCE/ORIGIN OF PEPTIDE	SMILES	CELL LINE	In vitro CONCENTRATION	In vitro METHOD	In vitro RESULT	ANIMAL MODEL	In vivo CONCENTRATION	In vivo MODE OF DELIVERY	In vivo METHOD	In vivo RESULT	ACTION	TRANSPORT TYPE	SUBCELLULAR LOCALISATION	COMBINATION	PHYSICAL CONDITION	RESPONSE	RESULT	LABEL	PMID
B3pdbIDb3pdb_0004	PEPTIDE NAMENA	PEPTIDE SEQUENCE (1-letter)SLKP	PEPTIDE SEQUENCE (3-letter)SerLeuLysPro	N-TERMINAL MODIFICATIONNA	C-TERMINAL MODIFICATION NA	CHEMICAL MODIFICATION5(6)-carboxyfluorescein attched to peptide	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONLinear	PEPTIDE NATURENA	SOURCE/ORIGIN OF PEPTIDEDodeca-neuropeptide (SLKPAANLPLRF) of frog brain.	SMILESN[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)O	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELRat primary cortical neurons	In vivo CONCENTRATIONNA	In vivo MODE OF DELIVERYIntraperitoneal	In vivo METHODFourier Transform Infrared Spectroscopy	In vivo RESULTInhibition of Aβ fibrillation	ACTIONIt inhibits Aβ fibrillization, moderately binds with tubulin and promotes tubulin polymerization as	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONAlzheimer’s disease	RESPONSENA	RESULTNA	LABELNA	PMID 30408415
B3pdbIDb3pdb_0047	PEPTIDE NAMEC-TN-APNPs	PEPTIDE SEQUENCE (1-letter)CAQK	PEPTIDE SEQUENCE (3-letter)CysAlaGlnLys	N-TERMINAL MODIFICATIONNA	C-TERMINAL MODIFICATION NA	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONLinear	PEPTIDE NATURENA	SOURCE/ORIGIN OF PEPTIDEChemically synthesized	SMILESN[C@@]([H])(CS)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCCCN)C(=O)O	CELL LINEhCMEC/D3 and NHA cells	In vitro CONCENTRATIONNA	In vitro METHODTEM imaging	In vitro RESULTResponsive to thrombin cleavage, reduced the cytotoxicity of Tat-NR2B9c, and increased BBB permeabil	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATIONNA	In vivo MODE OF DELIVERYIntravenous	In vivo METHODDynamic light scattering	In vivo RESULTBetter circulation time, better targeting ability and penetrating efficiency to the injured brain, a	ACTIONTreatment reduced the injury size	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONCombined with Tat-NR2B9c	PHYSICAL CONDITIONTraumatic brain injury	RESPONSENA	RESULTNA	LABELNA	PMID 31213815
B3pdbIDb3pdb_0048	PEPTIDE NAMECC-TN-APNPs	PEPTIDE SEQUENCE (1-letter)CCAQK	PEPTIDE SEQUENCE (3-letter)CysCysAlaGlnLys	N-TERMINAL MODIFICATIONNA	C-TERMINAL MODIFICATION NA	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH5	PEPTIDE CONFORMATIONLinear	PEPTIDE NATURENA	SOURCE/ORIGIN OF PEPTIDEChemically synthesized	SMILESN[C@@]([H])(CS)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCCCN)C(=O)O	CELL LINEhCMEC/D3 and NHA cells	In vitro CONCENTRATIONNA	In vitro METHODTEM imaging	In vitro RESULTResponsive to thrombin cleavage, reduced the cytotoxicity of Tat-NR2B9c, and increased BBB permeabil	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATIONNA	In vivo MODE OF DELIVERYIntravenous	In vivo METHODDynamic light scattering	In vivo RESULTBetter circulation time, better targeting ability and penetrating efficiency to the injured brain, a	ACTIONTreatment reduced the injury size	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONCombined with Tat-NR2B9c	PHYSICAL CONDITIONTraumatic brain injury	RESPONSENA	RESULTNA	LABELNA	PMID 31213815
B3pdbIDb3pdb_0067	PEPTIDE NAMEHAVN2	PEPTIDE SEQUENCE (1-letter)SHAVS	PEPTIDE SEQUENCE (3-letter)SerHisAlaValSer	N-TERMINAL MODIFICATIONNA	C-TERMINAL MODIFICATION NA	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH5	PEPTIDE CONFORMATIONCyclic	PEPTIDE NATURENA	SOURCE/ORIGIN OF PEPTIDEChemically synthesized	SMILESN[C@@]([H])(CO)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)O	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATIONNA	In vivo MODE OF DELIVERYIntracerebral ventricular	In vivo METHODMass Spectromtery	In vivo RESULTIt is able to deliver an IRdye800CW-labeled IgG monoclonal antibody into the brain.	ACTIONSynthesized novel cyclic peptides are able efectively modulate the BBB to enhance the delivery of mA	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONCombined with monoclonal antibody	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 31683745
B3pdbIDb3pdb_0077	PEPTIDE NAMELeu-Enkephalins	PEPTIDE SEQUENCE (1-letter)YGGFL	PEPTIDE SEQUENCE (3-letter)Tyr-Gly-Gly-Phe-Leu	N-TERMINAL MODIFICATIONNA	C-TERMINAL MODIFICATION NA	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH5	PEPTIDE CONFORMATIONPentapeptide	PEPTIDE NATURENA	SOURCE/ORIGIN OF PEPTIDEIntestine and Brain	SMILESN[C@@]([H])(Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)O	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELAdult Wistar SPF rats	In vivo CONCENTRATIONNA	In vivo MODE OF DELIVERYNA	In vivo METHODNA	In vivo RESULTNA	ACTIONmorphine-like actions and addictive properties	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 744146
B3pdbIDb3pdb_0078	PEPTIDE NAMEMet-Enkephalins	PEPTIDE SEQUENCE (1-letter)YGGFM	PEPTIDE SEQUENCE (3-letter)Tyr-Gly-Gly-Phe-Met	N-TERMINAL MODIFICATIONNA	C-TERMINAL MODIFICATION NA	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH5	PEPTIDE CONFORMATIONPentapeptide	PEPTIDE NATURENA	SOURCE/ORIGIN OF PEPTIDEIntestine and Brain	SMILESN[C@@]([H])(Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCSC)C(=O)O	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELAdult Wistar SPF rats	In vivo CONCENTRATIONNA	In vivo MODE OF DELIVERYNA	In vivo METHODNA	In vivo RESULTNA	ACTIONmorphine-like actions and addictive properties	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 744146
B3pdbIDb3pdb_0080	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH2	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT70% maximum possible effect after 5 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0081	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH3	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT100% maximum possible effect after 15 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0082	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH4	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT100% maximum possible effect after 30 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0083	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH5	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT100% maximum possible effect after 60 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0084	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH6	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT100% maximum possible effect after 120 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0085	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH7	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT40% maximum possible effect after 5 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0086	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH8	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT80% maximum possible effect after 15 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0087	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH9	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT80% maximum possible effect after 30 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0088	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH10	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT90% maximum possible effect after 60 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0089	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH11	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT100% maximum possible effect after 120 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0090	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH12	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT10% maximum possible effect after 5 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0091	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH13	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT40% maximum possible effect after 15 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0092	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH14	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT70% maximum possible effect after 30 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0093	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH15	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT80% maximum possible effect after 60 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0094	PEPTIDE NAMEBVDO2	PEPTIDE SEQUENCE (1-letter)DmtNmeAFS-NH16	PEPTIDE SEQUENCE (3-letter)H-Dmt-Nme-D-Ala-Phe-Ser-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONNA	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT30% maximum possible effect after 120 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0095	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH2	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION4 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT10% maximum possible effect after 5 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0096	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH3	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION4 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT40% maximum possible effect after 15 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0097	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH4	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION4 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT70% maximum possible effect after 30 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0098	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH5	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION4 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT70% maximum possible effect after 60 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0099	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH6	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION4 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT50% maximum possible effect after 120 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0100	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH7	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT10% maximum possible effect after 5 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0101	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH8	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT50% maximum possible effect after 15 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0102	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH9	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT70% maximum possible effect after 30 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0103	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH10	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT90% maximum possible effect after 60 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0104	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH11	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT90% maximum possible effect after 120 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0105	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH12	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT30% maximum possible effect after 5 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0106	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH13	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT40% maximum possible effect after 15 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0107	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH14	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT40% maximum possible effect after 30 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0108	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH15	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT90% maximum possible effect after 60 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0109	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH16	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.5 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT90% maximum possible effect after 120 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0110	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH17	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.25mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT30% maximum possible effect after 5 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0111	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH18	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.25mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT30% maximum possible effect after 15 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0112	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH19	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.25mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT30% maximum possible effect after 30 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0113	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH20	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.25mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT40% maximum possible effect after 60 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0114	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)Dmt-N-Me-D-AAbaG-NH21	PEPTIDE SEQUENCE (3-letter)Dmt-N-Me-D-Ala-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at alanine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION0.25mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT50% maximum possible effect after 120 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0115	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)H-Dmt-D-RAbaG-NH2	PEPTIDE SEQUENCE (3-letter)H-Dmt-D-Arg-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at arginine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION4 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT30% maximum possible effect after 5 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0116	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)H-Dmt-D-RAbaG-NH3	PEPTIDE SEQUENCE (3-letter)H-Dmt-D-Arg-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at arginine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION4 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT100% maximum possible effect after 15 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0117	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)H-Dmt-D-RAbaG-NH4	PEPTIDE SEQUENCE (3-letter)H-Dmt-D-Arg-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at arginine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION4 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT100% maximum possible effect after 30 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0118	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)H-Dmt-D-RAbaG-NH5	PEPTIDE SEQUENCE (3-letter)H-Dmt-D-Arg-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at arginine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION4 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT100% maximum possible effect after 60 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0119	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)H-Dmt-D-RAbaG-NH6	PEPTIDE SEQUENCE (3-letter)H-Dmt-D-Arg-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at arginine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION4 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT100% maximum possible effect after 120 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0120	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)H-Dmt-D-RAbaG-NH7	PEPTIDE SEQUENCE (3-letter)H-Dmt-D-Arg-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at arginine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT30% maximum possible effect after 5 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0121	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)H-Dmt-D-RAbaG-NH8	PEPTIDE SEQUENCE (3-letter)H-Dmt-D-Arg-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at arginine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT60% maximum possible effect after 15 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0122	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)H-Dmt-D-RAbaG-NH9	PEPTIDE SEQUENCE (3-letter)H-Dmt-D-Arg-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at arginine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT90% maximum possible effect after 30 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619
B3pdbIDb3pdb_0123	PEPTIDE NAMEBVDO3	PEPTIDE SEQUENCE (1-letter)H-Dmt-D-RAbaG-NH10	PEPTIDE SEQUENCE (3-letter)H-Dmt-D-Arg-Aba-Gly-NH2	N-TERMINAL MODIFICATIONMethylation	C-TERMINAL MODIFICATION Amidation	CHEMICAL MODIFICATIONAddition of amiNAbenzoic acid at arginine	PEPTIDE LENGTH4	PEPTIDE CONFORMATIONTetrapeptide	PEPTIDE NATURECationic	SOURCE/ORIGIN OF PEPTIDENA	SMILESNA	CELL LINENA	In vitro CONCENTRATIONNA	In vitro METHODNA	In vitro RESULTNA	ANIMAL MODELC57BL6 mice	In vivo CONCENTRATION1 mg/Kg	In vivo MODE OF DELIVERYIntravenous	In vivo METHODHot water tail flick test	In vivo RESULT100% maximum possible effect after 60 minutes	ACTIONCross BBB and shows morphine like action with analgesic effects	TRANSPORT TYPENA	SUBCELLULAR LOCALISATIONNA	COMBINATIONNA	PHYSICAL CONDITIONNA	RESPONSENA	RESULTNA	LABELNA	PMID 22289619