Detailed description page of B3Pdb


This page provides detail information of Selected ID b3pdb_0004
Primary information
B3PDB IDb3pdb_0004
Peptide NameNA
PEPTIDE SEQUENCE (1-letter)SLKP
PEPTIDE SEQUENCE (3-letter)SerLeuLysPro
N-terminal modificationNA
C-terminal modificationNA
Chemical modification5(6)-carboxyfluorescein attched to peptide
Peptide Length4
ConformationLinear
Peptide NatureNA
Source/Origin of peptideDodeca-neuropeptide (SLKPAANLPLRF) of frog brain.
SMILESN[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)O
Cell LineNA
In vitro CONCENTRATIONNA
In vitro METHODNA
In vitro RESULTNA
ANIMAL MODELRat primary cortical neurons
In vivo CONCENTRATIONNA
In vivo MODE OF DELIVERYIntraperitoneal
In vivo METHODFourier Transform Infrared Spectroscopy
In vivo RESULTInhibition of Aβ fibrillation
ACTIONIt inhibits Aβ fibrillization, moderately binds with tubulin and promotes tubulin polymerization as
TRANSPORT TYPENA
SUBCELLULAR LOCALISATIONNA
COMBINATIONNA
PHYSICAL CONDITIONAlzheimer’s disease
RESPONSENA
RESULTNA
LABELNA
PMID30408415