Detailed description page of B3Pdb
This page provides detail information of Selected ID b3pdb_0004 |
| Primary information | |
|---|---|
| B3PDB ID | b3pdb_0004 |
| Peptide Name | NA |
| PEPTIDE SEQUENCE (1-letter) | SLKP |
| PEPTIDE SEQUENCE (3-letter) | SerLeuLysPro |
| N-terminal modification | NA |
| C-terminal modification | NA |
| Chemical modification | 5(6)-carboxyfluorescein attched to peptide |
| Peptide Length | 4 |
| Conformation | Linear |
| Peptide Nature | NA |
| Source/Origin of peptide | Dodeca-neuropeptide (SLKPAANLPLRF) of frog brain. |
| SMILES | N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)O |
| Cell Line | NA |
| In vitro CONCENTRATION | NA |
| In vitro METHOD | NA |
| In vitro RESULT | NA |
| ANIMAL MODEL | Rat primary cortical neurons |
| In vivo CONCENTRATION | NA |
| In vivo MODE OF DELIVERY | Intraperitoneal |
| In vivo METHOD | Fourier Transform Infrared Spectroscopy |
| In vivo RESULT | Inhibition of Aβ fibrillation |
| ACTION | It inhibits Aβ fibrillization, moderately binds with tubulin and promotes tubulin polymerization as |
| TRANSPORT TYPE | NA |
| SUBCELLULAR LOCALISATION | NA |
| COMBINATION | NA |
| PHYSICAL CONDITION | Alzheimer’s disease |
| RESPONSE | NA |
| RESULT | NA |
| LABEL | NA |
| PMID | 30408415 |