EbolaVCR: Computational resources for designing drugs and vaccines against EBOLA virus

Welcome to Home page of EbolaVCR



Ebola Virus Computational Resources (EbolaVCR) is the in silico resources developed to facilitate scientific community fighting against deadly virus EBOLA. This server enlists possible vaccine candidates, therapeutic siRNAs and other related resources.
Reference: Dhanda et. al. (2016) A web-based resource for designing therapeutics against Ebola Virus. Sci Rep. 6:24782.

Target/Gene Wise Distribtition of siRNA

This page provides information about exclusive siRNA antisense sequences targeting 43 genes across the 5 species of Ebola. Further information can be obtained by clicking on gene/protein name, total siRNAs found effective and highly efficacious siRNA constructs.

Gene nameSymbol Species
Bundibugyo Ebola Virus (BDBV)Reston Ebola Virus (RESTV)Sudan Ebola Virus (SUDV)Tai-Forest Ebola Virus (TAFV)Ebola Virus Mayinga Zaire(EBOV-May)
RNA PolymeraseLYP_003815440.1NP_690587.1YP_138527.1YP_003815431.1NP_066251.1
Major NucleoproteinNPYP_003815432.1NP_690580.1YP_138520.1YP_003815423.1NP_066243.1
Membrane associated proteinVP24YP_003815439.1NP_690586.1YP_138526.1YP_003815430.1NP_066250.1
Minor nucleoproteinVP30YP_003815438.1NP_690585.1YP_138525.1YP_003815429.1NP_066249.1
Polymerase complexVP35YP_003815433.1NP_690581.1YP_138521.1YP_003815424.1NP_066244.1
Matrix proteinVP40YP_003815434.1NP_690582.1YP_138522.1YP_003815425.1NP_066245.1
Glycoprotein (Spike)GPYP_003815435.1NP_690583.1YP_138523.1YP_003815426.1NP_066246.1
Glycoprotein (Small Secreted)sGPYP_003815436.1NP_690584.1YP_138524.1YP_003815427.1NP_066247.1
Glycoprotein (Second Secreted)ssGPYP_003815437.1YP_003815428.1NP_066248.1NANA