Browse result page of TopicalPdb


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IDSequenceNameNature of peptide or cargoAssayTissue permeabilityTissue SamplePUBMED ID
1622pyroGHWSYlRP-NHEtLeuprolideNot mentionedHPLC5 mg/mLhuman skin from tummy-tuck surgery (when available) or frozen skin from skin banks2118954
1624pyroGHWSYlRP-NHEtLeuprolide (Lupron)It is a useful model peptide for evaluating transdermal administration of peptide drugs.Amerlex LH RIA kit From the transdermal route the peak response was 76.9 ± 99.8 mIU/ mlHuman skin2121407
1625PyroGlu-HWSYGLRPGGnRH (gonadotropin releasing hormone)Gonadotropin releasing hormoneHPLCConcentration of GnRH in the receptor after 1 hour was 4,2 uM and after 4 hrs was 6,4 uM.Hairless mouse skin2203894
1638pyroGHWSYlRP-NHEtLeuprolideNot mentionedIontophoresis permetaion studiesSerum luteinizing hormone concentration was measured 12 times during an 8 hr period. Significant elevations of LH were seen in active compared with passive patches.(56.4 +- 49.6 mIU/ml) at 4hrs.human skin3143511
1651PyroGlu-HWSYGLRPGLeuteinzing hormone releasing hormone(LHRH)Not mentionedSingle antibody radioimmunoassayThe total amount of LHRH delivered during the 5h was 959 +- 444 ng.old female yorkshire pigs8360818